Pilot lyophilizers for pharmaceutical development
When working on the development of therapeutic proteins or ADC production for clinical trials, precise control over the lyophilization process is crucial. Ensuring high-quality outputs while handling small to medium batch productions in cleanroom environments can be challenging.
Automate and control freeze-drying processes
The Hull LyoConstellation S10, S20, and S30 Pilot Lyophilizers from ATS Scientific Products offer scalable and flexible freeze-drying solutions designed to meet GMP standards. The units integrate with SP’s Line of Sight™ suite of Process Analytical Technologies (PAT) to automate, control, and support the entire lyophilization process, ensuring efficiency, quality, and consistency. With capabilities to hold vials up to 30 mL and maintain 100 mTorr while shelves are at +40°C, these lyophilizers support aggressive freeze-drying cycles. They feature controlled ice nucleation, fluid condenser cooling, and large diameter vapor ports for high vapor flow. Additionally, the system is equipped with critical PAT tools like LyoFlux® 200 TDLAS Sensors for water vapor mass flow measurement, SMART™ Freeze Dryer Technology for real-time data feedback, TEMPRIS® Wireless Sensors for wireless temperature monitoring, and ControLyo® Nucleation Technology for precise control over freezing points. The LyoConstellation series is also prepared for full steam or H2O2 cleaning in place (CIP/SIP) and validated with built-in ports and documentation.
Benefits
- Enhanced process control with integrated PAT tools
- Supports aggressive freeze-drying cycles
- Full cleanroom compatibility and SIP/CIP execution
- Scalability through consistent software and technology options
- Faster market delivery with configured-to-order options