Single-use bioreactors for mammalian cell culture
In modern biopharmaceutical processes, scalability and flexibility in cell culture are essential for efficient production. However, traditional stainless steel systems complicate quick succession of batches due to extensive cleaning and sterilization cycles.
Simplify cell cultivation with disposable culture vessels
The single-use bioreactor, offered by Sartorius AG, is an innovative solution designed to streamline cell culture processes. Utilizing a pre-sterilized plastic bag as the culture vessel, this system eliminates lengthy cleaning and sterilization steps required by traditional stainless steel bioreactors. This leads to significant reductions in turnaround time between production batches. The bioreactors are compatible with integrated single-use sensors and various process analytic technologies (PAT), allowing for real-time monitoring and process control. The Sartorius single-use bioreactors come in sizes ranging from 15 mL to 2,000 L, making them suitable for applications from research and development to commercial-scale production. They are particularly advantageous for mammalian cell cultures, offering excellent and reproducible growth behavior even for sensitive cell lines. The robust Flexsafe® film used in these bioreactors ensures durability and performance consistency, backed by a secure supply chain ensured through strategic long-term partnerships with resin and film suppliers.
Benefits
- Reduced turnaround time between batches
- No need for cleaning and sterilization
- Flexibility in process setup
- Real-time process monitoring
- Consistent growth behavior for sensitive cell lines