Benchtop bioreactor for research and development

Achieve precise control over fermentation and cultivation processes with advanced benchtop bioreactors, enabling groundbreaking research and development in biotechnology across small and scalable operations.

Cultivates and Monitors Cell and Microbial Cultures

The AUXO V® from n!Biomachines is a versatile benchtop bioreactor engineered for precision in biotechnological applications. It excels in cultivating and monitoring both cell and microbial cultures for industries including biotech and pharmaceuticals. With capacities ranging from 1 to 200 liters, it utilizes advanced sensors for precise control of temperature, pH, and oxygen levels, which are crucial for experimental accuracy. The integration of a Siemens PLC and touch-screen controls facilitates seamless automation and remote monitoring, streamlining operations in research labs. Equipped with stainless steel vessels at larger scales, it ensures durability and ease of sterilization, adhering to stringent industry standards. Customizable options accommodate a wide range of processes like fermentation and sampling, supported by engineering expertise to develop tailored solutions for innovative bioprocessing.

Benefits

  • Enhances process precision and reliability with advanced sensory control for optimal culture conditions.
  • Facilitates seamless scaling from lab to pilot-scale, ensuring efficient transition and reduced time to market.
  • Offers customizable configurations to meet diverse bioprocessing requirements, promoting flexible research adaptability.
  • Reduces overhead costs with efficient space utilization and robust design tailored for compact laboratory settings.
  • Enables rapid experimentation and data-driven optimization through sophisticated data monitoring and analysis tools.

General


Applications
Cell culture,Nutraceuticals,Microbial culture,Biopharmaceuticals,Enzymes,Cultivated meat,Alternative protein
End products
Plant-based protein isolates,Mammalian cell cultures,Industrial enzymes,Monoclonal antibodies,Yeast cultures,Probiotics supplements,Lab-grown meat
Steps before
Preparation of culture medium,Inoculation of microorganisms or cell lines,Calibration of sensors,Configuration of cultivation program
Steps after
Data analysis and optimization,Harvesting of cultured product,Sterilization,Cleaning in place (CIP) or Sterilization in place (SIP)
Input ingredients
mammalian cell lines,avian cell lines,fish cell lines,bacteria,yeast,culture media,oxygen,CO2,N2,compressed air
Output ingredients
high-density fermentation,protein production,yield optimization,biological processes insights,cultivated meat
Market info

Technical Specifications


Culture vessel sizes
1L,2L,3L,5L,7L,15L,50L,100L,200L
Material
Glass (1L-15L),Stainless steel (15L-200L)
Multi-use capability
Yes
Impeller blades
Rushton,marine,pitched-blade
Sterilization systems
CIP/SIP
Sensors
Hamilton DO/O2,Hamilton pH,Temperature Pt 100
Oxygen sensor resolution
0.1% resolution
PH sensor range
5 – 8 (0.1 resolution)
Temperature sensor range
0 – 100°C (0.1°C resolution)
Fluid pumps
High precision Watson Marlow,6-8 peristaltic pumps
Pump speed
0-600 RPM
Controller
Siemens PLC
Interface
Touch panel 10’’
Gas control valves
4 valves for compressed air,oxygen,CO2,and N2
Software
Pre-configured cultivation programs
Monitoring
Web-based remote monitoring

Operating Characteristics


Precision control environment
Temperature,pH,oxygen levels
Automation level
PLC / Touch screen
CIP/SIP
CIP available for larger vessels
Changeover time
Customizable configurations for quick setup
Advanced data monitoring
Web-based remote monitoring
Air control
4 gas control valves (air,oxygen,CO2,N2)
Batch vs. continuous operation
Batch

Material Compatibility


Biological compatibility
Yes
Cleanability
Easily maintained in a sustainable way
Corrosive resistance (e.g. acids)
Stainless steel option
Density/particle size
0.5–2.5 g/cm³

Product type Characteristics


Cultivation Options
Mammalian,Avian,Fish,Bacteria,Yeast

Physical Characteristics


Machine footprint
Compact design for limited lab space
Vessel size
1L,2L,3L,5L,7L,15L,50L,100L,200L
Material
Glass (1-15L) / Stainless Steel (15-200L)
Multi-use capability
Yes,for cost optimization
Impeller types
Rushton,marine,pitched-blade
Sterilization options
CIP/SIP for larger vessels

Custom Options


Control Panel Type
Touch panel 10’’ / Touch screen / Removable
Material Choice
Glass or Stainless Steel
Gas Control Valves
4 valves for compressed air,oxygen,CO2,and N2
Sensors
Hamilton DO/O2 and pH,temperature,foam,glucose,lactate
Pump Configuration
6-8 high precision pumps,Watson Marlow technology
Software
Pre-configured cultivation programs
Configuration Size
1L to 200L