Industrial-scale bioreactors for large-scale biomanufacturing

When producing at large volumes, efficient and reliable bioprocess systems are crucial for ensuring consistent quality of biopharmaceuticals and alternative proteins while minimizing downtime.

Processes Large-Scale Bioproduction with Automation

The AUXO V® bioreactors from n!Biomachines Ltd. are engineered-to-order systems ideal for biomanufacturers seeking reliable scalability and automation in bioproduction. Specifically designed to handle capacities exceeding 5000 liters, these bioreactors are perfect for producing biopharmaceuticals, nutraceuticals, plant-based products, and cultivated meats. The bioreactors integrate advanced automation and remote monitoring, reducing downtime while boosting productivity. Featuring robust construction, they are well-equipped to manage the demands of continuous industrial-scale operations. The stainless steel construction ensures chemical compatibility and longevity. With PLC-controlled systems, these units offer seamless integration into existing production lines and support the upscaling of bioprocesses efficiently. Compliance with industry standards such as GMP ensures they are suitable for pharmaceutical applications. Moreover, the bioreactors include CIP (Clean-In-Place) systems for maintaining contamination-free operations. Tailor the bioreactors to your specific needs with a variety of customization options provided by n!Biomachines Ltd.’s engineering support.

Benefits

  • Increases production capacity with high-volume processing up to 5000 liters.
  • Minimizes operational downtime through robust construction and remote monitoring.
  • Enhances process consistency and efficiency with advanced automation and scalability.
  • Ensures regulatory compliance and product safety with GMP-standard design.
  • Simplifies maintenance and reduces contamination risk with integrated CIP systems.

General


Applications
Alternative proteins,Nutritional supplements,Nutraceuticals,Plant-based products,Biopharmaceuticals,Healthcare products,Cultivated meat
End products
Tissue-engineered skin grafts,Plant-based meat substitutes,Cultivated chicken meat,Omega-3 fatty acids,Human insulin,Monoclonal antibodies,Protein powder supplements,Plant-based milk
Steps before
Cell culture preparation,Media formulation,Inoculation
Steps after
Harvesting,Purification,Protein extraction
Input ingredients
biomass,nutrients,culture media
Output ingredients
bioproducts,proteins,cultivated meat
Market info

Technical Specifications


Capacity
Exceeds 5000 liters
Automation
Advanced automation systems
Durability
Robust and durable construction
Scalability
Designed for large-scale production
Monitoring
Remote and on-site monitoring

Operating Characteristics


Automation level
Advanced automation systems
Batch vs. continuous operation
Batch
High-volume capacity
5000+ liters
Scalability
Adaptable to increasing production demands
Remote and on-site monitoring
Yes
Durability
Robust and durable construction

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Volume Capacity
5000 liters+
Construction Material
Durable materials for industrial conditions
Customization Options
Fit-for-purpose configuration
Monitoring
Remote and on-site
Footprint
Compact for large-scale machinery

Custom Options


Capacity options
Exceeds 5000 liters
Automation level
Advanced automation systems
Scalability
Adaptable to increasing production demands
Customization options
Fit-for-purpose bioreactors
Monitoring type
Remote and on-site