Flow-through cell dissolution testing with Uv analysis
In pharmaceutical development and quality control, it is essential to assess the dissolution characteristics of APIs and various dosage forms accurately. Traditional methods often fall short in providing real-time data and reproducible results across different formulations and conditions.
Real-time dissolution analysis with Uv integration
The CE 7smart UV Online from Sotax AG is a comprehensive flow-through cell dissolution system that integrates UV-Vis analysis for real-time sample monitoring. Designed for testing APIs, oral, topical, and parenteral dosage forms, the CE 7smart allows rapid dissolution data acquisition by connecting to a spectrophotometer. The system’s CP pump fills flow cells linked to each dissolution vessel, and the spectrometer’s multi-cell changer measures each vessel instantly. It supports various UV-Vis brands and types, ensuring flexibility in operation. With its ability to handle volumes from 50 to 5000 mL and maintain consistent hydrodynamic conditions, the CE 7smart is ideal for both open and closed system settings. This apparatus is also capable of biorelevant media simulations, making it suitable for extended and delayed release forms as well as poorly soluble compounds (BCS class II and IV). Additionally, the CE 7smart uses SOTAX Dissolution software for method management, ensuring complete traceability and customizable reporting.
Benefits
- Immediate result acquisition through integrated UV-Vis analysis
- Flexible volume handling from 50 to 5000 mL
- Reproducible results for various dosage forms
- Biorelevant method compatibility
- Complete traceability with SOTAX Dissolution software