Aseptic filling and capping for vials and syringes
Ensure sterility and precision in vial and syringe filling with advanced containment solutions, offering bio-decontamination and environmental safety for high-potency drug production.
Fills and Caps Vials and Syringes Aseptically
The ISOL-AIR Series from the Marchesini Group provides a state-of-the-art solution for aseptic filling and containment tailored for pharmaceutical manufacturers and biotech companies. These containment cabinets, configurable as Closed RABS or Isolators, excel in filling and capping vials and syringes. Designed to support aseptic processes, they integrate seamlessly into your production line, optimizing filling capacities while ensuring operator and product protection. They cater to the production of vaccines, insulin, oncology drugs, and more, addressing complex sterile injectable requirements. The series features aseptic transfer connections through Rapid Transfer Ports (RTP) and is fully automated with a programmable Wash in Place (WIP) system, including manual spray guns for flexible cleaning options. The equipment supports bio-decontamination cycles by Vaporized Hydrogen Peroxide (VHP) and incorporates Environmental Monitoring Systems (EMS) for maintaining optimal processing conditions. Energy efficiency and product safety are prioritized with dedicated HVAC Air Handling Units (AHU) and Bag-IN/Bag-OUT filters for processing potent drugs. Marchesini Group’s commitment to quality ensures that these machines meet stringent pharmaceutical compliance standards, offering customizable configurations to suit your unique operational needs.
Benefits
- Ensures product and operator safety with advanced isolation and containment solutions.
- Reduces contamination risk with automated Wash in Place (WIP) and bio-decontamination systems.
- Enhances production efficiency with seamless integration into existing aseptic filling lines.
- Supports regulatory compliance with integrated Environmental Monitoring Systems (EMS).
- Offers flexible configuration options to meet specific operational and production demands.
- Applications
- Syringe filling,Vial filling,Biopharmaceuticals,Aseptic processing,Pharmaceuticals
- End products
- Blood plasma derivatives,Hormones for injection,Biologics,Vaccines,Sterile injectables,Antiviral medications,Insulin,Monoclonal antibodies,Injectable antibiotics,Oncology drugs
- Steps before
- Washing,Sterilizing
- Steps after
- Bio-decontamination,Environmental Monitoring
- Input ingredients
- vials,syringes,potent drugs
- Output ingredients
- filled vials,capped vials,filled syringes,stoppered syringes
- Market info
- Marchesini is renowned for manufacturing high-quality packaging machinery for the pharmaceutical and cosmetics industries, offering innovative, customized solutions with advanced automation and technology.
- Containment type
- ISOLATED LINE FOR VIAL FILLING
- Configuration
- Closed RABS or Isolator
- Aseptic transfer connections
- RTP (Rapid Transfer Ports)
- Environmental Monitoring System
- Integrated EMS
- Air recovery ducts
- Bag-IN / Bag-OUT filters
- Wash in Place system
- Automatic WIP,manual spray guns
- Bio-decontamination cycle
- Vaporized Hydrogen Peroxide (VHP)
- Dedicated HVAC Units
- AHU (Air Handling Units)
- Automation level
- Manual / PLC / SCADA
- Batch vs. continuous operation
- Batch / Inline Continuous
- Cleaning method
- CIP / Manual
- CIP/SIP
- CIP 121°C / SIP 135°C
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Air recovery system
- Bag-IN / Bag-OUT filters
- Isolation level
- Closed RABS or Isolator
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Containment configuration
- Closed RABS / Isolator
- Aseptic transfer connection type
- RTP (Rapid Transfer Ports)
- Cabinet feature
- Containment
- Air recovery ducts with filter
- Bag-IN / Bag-OUT filters
- Line division capability
- Independent sections
- Bio-decontamination method
- Vaporized Hydrogen Peroxide (VHP)
- HVAC Air Handling Units (AHU)
- Dedicated
- Containment Configuration
- Closed RABS / Isolator
- Environmental Monitoring System
- Integrated EMS
- Air Recovery Duct Filters
- Bag-IN / Bag-OUT filters
- Automatic Wash in Place
- Automatic WIP system
- Section Division
- Independent sections
- Bio-decontamination Method
- Vaporized Hydrogen Peroxide (VHP)
- HVAC Air Handling Units
- Dedicated HVAC AHU
- Transfer Connections
- RTP (Rapid Transfer Ports)