Small-scale freeze dryer for pharmaceutical applications
Optimize small-batch and pilot-scale lyophilization with advanced freeze-drying technologies designed to ensure product quality, uniformity, and process reliability, achieving efficient moisture removal for biopharmaceutical applications.
Freeze Dries Small-Batch Biopharmaceuticals
The MINIMAX Small-Scale Freeze Dryer from IMA Life is a GMP-compliant solution designed to tackle the challenges of handling small production batches in the pharmaceutical and biotech industries. Built on the successful LYOMAX industrial freeze dryer concept, it offers unparalleled precision in moisture removal for sensitive biopharmaceuticals, such as vaccines, monoclonal antibodies, and gene therapy products.
This versatile lyophilizer features a compact and modular design, ideal for pilot-scale and small-scale production. It operates using process analytical technologies (PAT) for optimal monitoring and control, ensuring consistent drying outcomes and high product quality. With shelf areas ranging from 1.0 to 3.9 m² and an ice condenser capacity from 29 to 78 kg, the MINIMAX efficiently scales processes up to full commercial production.
Integration options include automation with vial-loading systems, PLC control, and compatibility with isolation technology for high-potent product handling. The unit is pre-arranged for more complex applications, such as processing non-aqueous solvents. Made with IMA Life’s proprietary FUSION™-FUSION PLUS™ technology, its shelves enhance heat transfer and offer robust resistance.
The Freeze Dryer supports extensive data collection, aiding in quick drug commercialization and allowing seamless adaptation to GMP standards. A built-in CIP-SIP system ensures effective cleaning and maintenance, minimizing downtime. Furthermore, options for monitoring tools like Veriseq™, a Quantum mass spectrometer, and WiSe wireless sensors enable precise control over every batch process, maximizing uptime and operational efficiency.
Benefits
- Ensures high-quality lyophilization with precise PAT monitoring, reducing the risk of product variability.
- Enhances scalability from pilot to commercial production, allowing seamless process transitions.
- Minimizes operational costs with preventive maintenance software, reducing unexpected downtimes.
- Accommodates high-potent product handling with integration-ready isolation technology.
- Facilitates regulatory compliance with GMP design and advanced cleaning systems.
- Applications
- High potent products,Biopharmaceuticals,Liquid formulations,Parenteral products
- End products
- Biologics,Lyophilized protein drugs,Vaccines,Injectable cancer drugs,Gene therapy products,Monoclonal antibodies,Insulin formulations,Liposomal formulations
- Steps before
- Formulation,Pilot-scale freeze drying,Scalable lyophilization technologies
- Steps after
- Packing,Sterilization,Commercial Production,Integration with isolation technology,Vial-loading
- Input ingredients
- small production batches,non-aqueous solvents,high potent products
- Output ingredients
- lyophilized pharmaceuticals,parenteral products,dried vials
- Market info
- IMA is known for its expertise in manufacturing automated packaging machines and solutions, particularly for the pharmaceutical, cosmetics, food, tea, and coffee industries, offering innovative, high-quality equipment and comprehensive customer service.
- Shelf Area Range
- 1.0 to 3.9 m²
- Condenser Capacity
- 29 to 78 kg
- Minimum Condenser Temperature
- -75°C
- RABS/Isolator Integration
- Slot door suitable
- Configuration
- Compact and modular
- Automation
- Integrated with isolation technology and automatic vial-loading systems
- PAT Tools
- Veriseq™ controlled nucleation,Quantum mass spectrometer,WiSe wireless temperature sensors
- Number of Shelves
- 3 to 7,with options
- Shelf Size
- 643 x 615 mm,643 x 930 mm
- Max Vials Loading Capacity
- 2R vial
- Batch vs. continuous operation
- Batch
- CIP/SIP
- Included
- Energy efficiency
- High-level redundancy
- Automation level
- Integrated with Isolation technology and automatic vial-loading systems
- Cleaning method
- CIP / SIP
- Changeover time
- Reduced downtime
- Container size and shape
- Suitable for vials,ampoules,and other parenteral containers
- Machine footprint
- Compact and modular
- Shelf Area Range
- 1.0 to 3.9 m²
- Shelf Spacing
- 106 or 136 mm
- Shelf Size
- 643 x 615 mm or 643 x 930 mm
- Number of Shelves
- 3 to 7 (with alternatives)
- Slot door integration
- RABS/isolator integration
- Condenser Capacity
- 29 to 78 kg
- Minimum Condenser Temperature
- -75°C
- Compact footprint
- Yes
- Control panel type
- Touchscreen HMI
- Integration capability
- RABS/Isolator integration
- Modular configuration
- Yes
- Shelf design
- FUSION™ technology
- Customizable shelf area
- 1.0 to 3.9 m²
- Automation level
- Pre-arranged for PAT tools integration
- Redundancy options
- High level