Radiopharmaceuticals dispensing isolator

Ensure precise and sterile dispensing of radiopharmaceuticals and other liquid formulations with cutting-edge shielding and filtration, optimizing safe handling and quality compliance in critical medical environments.

Dispenses, Calibrates, and Shields Radiopharmaceuticals

The TALIA Series, from Comecer, offers a state-of-the-art solution for radiopharmaceutical dispensing and shielding, with a focus on safety and compliance. This isolator features a laminar flow Class A chamber and up to 100mm lead shielding to protect operators. Ideal for radiopharmaceuticals, it efficiently handles dispensing, filling, calibrating, and fractioning with integrated automation and monitoring via a 17” touch-screen panel. The TALIA Series is specifically designed for operations involving fluorodeoxyglucose (FDG) doses, Lutetium-177, and Technetium-99m radiotracers, supporting sterile vial and syringe fills up to 30 vials or 10 syringes per batch. With internal monitoring of critical parameters and compliance with cGMP protocols, it ensures product quality and operator safety. This isolator integrates seamlessly into both manual and automated production lines, offering energy efficiency through optimized filtration and shielding, and is supported by Comecer’s engineering for customization and maintenance.

Benefits

  • Enhances operator safety with comprehensive lead shielding and controlled environments.
  • Ensures consistent product quality with integrated cGMP-compliant operations.
  • Increases efficiency through automated, touch-screen controlled processing.
  • Facilitates versatile production with compatibility for both vial and syringe dosing.
  • Minimized contamination risk with laminar flow and advanced filtration systems.

General


Applications
Sterile fill-finish operations,Nuclear medicine,Radiopharmaceuticals,Pharmaceutical formulations
End products
Sterile syringe fills,Iodine-131 therapy capsules,Technetium-99m radiotracers,Lutetium-177 radiopharmaceuticals,Sterile vial fills,Fluorodeoxyglucose (fdg) doses
Steps before
Material Introduction,Dose Calibration
Steps after
Dispensing,Product Extraction
Input ingredients
radiopharmaceuticals,vials,syringes,technical gas
Output ingredients
calibrated radiopharmaceutical doses,filled vials,filled syringes,waste materials
Market info
Comecer is known for manufacturing advanced containment and isolation systems, particularly in the pharmaceutical and nuclear medicine sectors, with expertise in custom-engineered equipment, ensuring high safety and compliance standards.

Technical Specifications


Lead shielding
Up to 100 mm
Work chamber ergonomics
Spacious
Airlock air quality
Class B "At rest" (EEC-cGMP)
Shielded compartments
Two
Operator panel
17” touch-screen
Pressure
Negative or Positive
Temperature monitoring
Internal
Humidity monitoring
Internal
Pressure adjustment
Modulating valves
Batch size
30 vials / 10 syringes
Material
304 AISI,316L AISI stainless steel
Internal surface finish
Mirror-Bright
Gasket system
Inflatable
Airflow
Laminar flow
Filtration type
ULPA U15 / HEPA
Gas supply lines
1/8”,6 mm with shut-off valves
Power supply sockets
Protected,operator panel-controlled
Pneumatic dragging system
Equipped
Dose calibrator
Pass-through
Bubble Point Test
Semi-automatic

Operating Characteristics


Batch vs. continuous operation
Batch
Laminar flow
Class A chamber
Pressure control
Negative or positive pressure in dispensing chamber
Automation level
17” touch-screen operator panel
Product extraction system
Double airlock with Class B and C air quality
Compliance with cGMP standards
Yes
Automatic adjustments
Modulating valves for inner pressure
Protection against ionising radiation
Complete shielding
Remote handling
Tele-pliers

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm


GMP Compliance
cGMP standards

Physical Characteristics


Material
316L AISI stainless steel
Surface Finish
Mirror-Bright
Lead Shielding Thickness
Up to 100 mm
Main Chamber Air Quality
Class A (EEC-cGMP)
Airlock Chamber Air Quality
Class B “At rest” (EEC-cGMP)
Work Chamber Ergonomics
Spacious
Control Panel Type
17” touch-screen operator panel
Product Extraction System
Shielded container with double airlock
Tele-pliers Mechanism
Special ball bearings for precision movement

Custom Options


Lead Shielding Thickness
Up to 100 mm
Chamber Ergonomics
Spacious work chamber
Material Introduction Chamber
Class B Airlock with Handling Gloves
Touch-screen Operator Panel
17" touch screen
Pressure Systems in Chambers
Constant Negative or Positive Pressure
Automation and Monitoring
Illuminate™ MI IIoT Platform
Internal Monitoring
Temperature and Humidity
Material Transfer
Material Transfer Tray
Waste Compartment
Class B Compartment
Technical Gas Supply Lines
1/8” and 6 mm with Shut-off Valves
Tele-pliers
Precision Movement with Ball Bearings
Filter Sealing Test
DOP Test Connection