Large-scale bioreactor for cell therapy manufacturing
Scaling up the production of therapeutic cells for commercial usage demands robust bioreactors capable of maintaining cell viability and product quality at high volumes. Traditional systems often fall short in volume capacity and process customization, leading to bottlenecks in manufacturing workflows.
Enable efficient cell therapy production at commercial scale.
The PBS-80 Vertical-Wheel Bioreactor from PBS Biotech is engineered for the large-scale manufacture of cell therapy products. With a working volume of up to 80 liters, it supports commercial-scale production seamlessly. The bioreactor offers a touchscreen interface for intuitive process customization and control, letting you easily manage parameters such as dissolved oxygen and pH. One of its unique features is the Adjustable Height Harvest Valve (AHHV), which allows rapid medium exchange and efficient cell harvesting. Configurations are available for both single-use and reusable sensors, providing flexibility based on your specific needs. Additionally, the bioreactor follows 21 CFR Part 11 requirements for cGMP, ensuring compliance and ease of qualification protocols. Ideal applications include the culture of anchorage-dependent human cells, including those grown on microcarriers or as cell aggregates.
Benefits
- High volume capacity of up to 80 liters
- Customizable process parameters via touchscreen interface
- Flexible sensor options: single-use or reusable
- Compliance with 21 CFR Part 11 for cGMP
- Efficient harvesting with Adjustable Height Harvest Valve (AHHV)