Nasal spray filling solution
For precise nasal spray production, achieve seamless filling, stoppering, and capping to ensure product sterility and dosage accuracy, maintaining consistency across batches.

Fills, Stoppers, and Caps Nasal Spray Containers
The Hull i-Dositecno Nasal Spray Filling Machine, available as the BI and MI models, offers a robust solution for pharmaceutical and biotech manufacturers seeking precise and efficient fill-finish processes. This machine excels in filling, stoppering, and capping operations using a servo-driven, motion-controlled design, capable of handling up to 50 or 200 units per minute.
Ideal for applications ranging from nasal decongestant sprays to liquid vaccine vials, it fills containers as small as 100µL up to 500mL. The equipment integrates seamlessly into your existing production line, utilizing Siemens or Allen Bradley PLC-controlled servo motors for precise output rate and flow adjustments.
Constructed with high-quality materials like POMc for change parts, the machine offers adaptable filling solutions via a peristaltic pump or rotary piston. It ensures strict compliance with regulatory standards, including 21 CFR Part 11, cGMP, and GAMP5, and comes equipped for integration into RABS and isolation systems for ultimate product protection.
The design includes features such as a mechanical unscrambler and dedicated hopper for efficient container feeding, while non-destructive In-Process Weight Control (IPC) maintains batch consistency. Cleaning is simplified with options for CIP/SIP processes, and comprehensive customization is supported by ATS Scientific Products’ dedicated engineering team.
Benefits
- Ensures product sterility and compliance with GMP and FDA standards, reducing regulatory risks.
- Offers precise filling accuracy, minimizing product waste and enhancing yield consistency.
- Adapts to various container sizes, reducing changeover times and increasing operational flexibility.
- Integrates seamlessly into existing production lines, optimizing workflow efficiency.
- Maintains batch consistency with non-destructive In-Process Weight Control (IPC), ensuring reliable output quality.
- Applications
- Liquid pharmaceuticals,Micro-dose liquid products,Pharmaceutical containers,Aseptic liquid formulations,Nasal sprays
- End products
- Antihistamine nasal sprays,Preservative-free nasal drops,Aseptic eye drop bottles,Liquid vaccine vials,Liquid vitamin supplements,Saline nasal rinses,Sterile saline solutions,Steroid nasal sprays,Nasal decongestant sprays
- Steps before
- Container Preparation,Component Sorting,Material Feeding
- Steps after
- Stoppering,Capping,Quality Control
- Input ingredients
- nasal spray solutions,bulk containers,plastic containers,liquid formulations,solid powder
- Output ingredients
- filled nasal spray containers,stoppered containers,capped containers,accurately dosed units
- Market info
- Filling speed
- 50–200 upm
- Filling volume
- 100µL to 500 mL
- Automation
- PLC-controlled
- Container type
- Multiple vial formats
- Dosing type
- Peristaltic pump / ceramic / SS rotary piston
- Cleanroom compatibility
- Cleanroom ready
- Changeover time
- Quick changeover with POMc change parts
- Automation level
- PLC-controlled servo motors
- Batch vs. continuous operation
- Batch
- Servo-driven motion control
- Yes
- In-Process Weight Control (IPC)
- 100%,non-destructive
- Cleanroom readiness
- Cleanroom compliant
- Flexibility in container size
- Multiple vial formats
- Product protection
- RABS / isolation technology
- Changeover time
- Quick changeover with POMc parts
- CIP/SIP
- Available
- Integrated steps
- Filling,stoppering,capping
- Cleanability
- Cleanroom ready
- Corrosive resistance (e.g. acids)
- Yes,for certain materials like stainless steel
- Biological compatibility
- Pharmaceutical-grade components
- Feed method
- Mechanical unscrambler,automatic container feed
- Control panel type
- Siemens or Allen Bradley PLC-controlled
- Control panel type
- Siemens/Allen Bradley PLC
- Discharge method
- Servo-driven motor
- Filling method
- Rotary Piston / Peristaltic Pump
- Filling nozzle configuration
- One or two filling nozzles
- Container handling
- Servo-driven star wheel transport
- Feeding system
- Mechanical unscrambler / Dedicated hopper
- Pick and place capability
- 2-channel for tips and caps
- Changeover parts material
- Polyoxymethylene Copolymer (POMc)
- Integration possibility
- Open/Closed RABS,Isolation Technology