Vertical-wheel bioreactor for cell therapy applications
Elevate your cell culture process with a bioreactor designed for precise parameter control and seamless scale-up, ensuring the efficient production of therapeutic cells and exosome-based therapeutics.

Cultures and Scales Therapeutic Cells
The PBS-3 Vertical-Wheel Bioreactor from PBS Biotech is designed to optimize your cell therapy production processes. This single-use, stirred suspension bioreactor offers customizable process parameters, effectively addressing complex needs in therapeutic cell cultivation, such as mixing, monitoring, and sampling. It caters to applications including MSC, hiPSC, CAR-T, and NK cell therapies, and is suitable for biotech and pharmaceutical industries. The bioreactor is engineered to simplify the scale-up process from laboratory to clinical trials, ensuring smooth transition to larger volumes. Featuring real-time data monitoring and process control, it allows remote access for adjustments and alarms via a secure interface. The system supports the integration of single-use or reusable sensors for DO and pH, meeting FDA and GMP standards. Available as a compact, bench-top system, it fits effortlessly into research and development environments, making it a versatile addition to your cell therapy production line.
Benefits
- Streamlines scale-up of therapeutic cell production from small to clinical volumes.
- Enhances cell culture consistency with precise parameter control and monitoring.
- Facilitates cost-effective operations with single-use vessels, eliminating cleaning requirements.
- Ensures regulatory compliance with FDA and GMP standards.
- Offers flexibility in process development through customizable and remote-access features.
- Applications
- Stem cells,Hipsc,Nk cells,Therapeutic cells,Cell therapy,Msc,Biopharmaceuticals,Exosomes,Car-t
- End products
- Car-t cell therapies,Nk cell therapies,Mesenchymal stem cell (msc) therapies,Induced pluripotent stem cell (ipsc) therapies,Exosome-based therapeutics
- Steps before
- Process Development,Small Scale Cell Culture Process Design
- Steps after
- Process Optimization,Data Analysis,Scale-Up to PBS-15 Bioreactor,Clinical Trials
- Input ingredients
- cell culture media,microcarriers,single cells,cell aggregates,sensors
- Output ingredients
- cultured cells,cellular products,data from process monitoring
- Market info
- PBS Biotech is known for manufacturing single-use, scalable bioreactor systems designed for cell therapy and biologics production, featuring their innovative Air-Wheel mixing technology for efficient and consistent results.
- Single-Use or Reusable Sensors
- Single-Use/Reusuable
- Bioreactor Volume
- 3L
- Touchscreen Interface
- Intuitive
- Process Customization
- User-configurable
- Real-time Monitoring
- Available
- Remote Monitoring Capability
- Yes
- Type of Bioreactor
- Vertical-Wheel
- Power Supply
- 120 V / 240 V
- Compliance
- 21 CFR Part 11 cGMP
- Bioreactor Installation
- Bench-top
- Hydrodynamic Performance
- High
- Process Scale-up Capability
- Yes
- Bioreactor Software
- v4 Software,3.0 Upgrade
- Automation level
- Touchscreen interface with customizable programming
- CIP/SIP
- Single-use vessels for easy cleaning and sterilization
- Batch vs. continuous operation
- Batch
- Remote monitoring
- Secure connection for process monitoring and adjustments
- Process scale-up
- Scalable from small-scale to larger 15L bioreactor
- Sensor compatibility
- Single-use or reusable DO and pH sensors
- Data storage and access
- 21 CFR Part 11 compliant
- Installation and operations qualification
- Protocols available for sale
- Footprint
- Lab Bench Compatible
- Vessel Type
- Single-Use / Reusable
- Control Panel
- Touchscreen Interface
- Impeller Type
- Floored / Floorless Vertical-Wheel
- Volume Capacity
- 3L Scale-Up
- Control panel type
- Touchscreen