Uv monitoring system for small volume dissolution studies

Efficiently monitor small-volume dissolution processes in real-time with UV spectrophotometry, ensuring precise data collection for comprehensive solubility and dissolution analysis.

Monitors and Analyzes Small Volume Drug Dissolution

The MicroDISS Profiler from Pion Inc. is an innovative UV monitoring system designed for small volume dissolution analysis in pharmaceutical and biotech environments. It utilizes dip-style probes made of stainless steel for durability and precise optical readings. Ideal for tablets, capsules, and powders, it excels in generating real-time dissolution profiles and handling complex solubility challenges. With its multi-channel capability, the system captures data at 1nm resolution across the UV/VIS spectrum every two seconds, ensuring comprehensive analysis of up to eight vessels simultaneously. The MicroDISS Profiler integrates seamlessly into R&D and laboratory settings, supporting a wide range of volumes and stirring speeds, offering a versatile solution for both aqueous and non-aqueous media analyses. Configurable pathlength tips enable cost-efficient adaptation to varying experimental needs, while its software platform provides robust data handling and visualization tools. The system is particularly suited for scenarios requiring detailed supersaturation and precipitation insight, supporting critical research on bioavailability and dissolution kinetics.

Benefits

  • Enhances analytical accuracy with simultaneous real-time data collection.
  • Increases efficiency in small volume dissolution testing for diverse formulations.
  • Supports comprehensive solubility analysis, aiding in faster R&D cycles.
  • Reduces operational costs with interchangeable pathlength tips for experimental flexibility.
  • Facilitates complex dissolution profile studies, improving product development insights.

General


Applications
Drug formulations,Pharmaceutical tablets,Nanoparticles,Films,Powders,Excipients,Capsules,Salts
End products
Intrinsic dissolution rate profiles,Loratidine hot melt extrudates,Biorelevant dissolution profiles,Supersaturation and precipitation models,Self-emulsifying lipid-based formulations
Steps before
Intrinsic dissolution,Pre-formulation analysis,Miniaturized sample preparation,Polymorphic form screening,Nanoparticle preparation
Steps after
Data analysis,Results evaluation,Bioavailability testing,Distribution phase analysis
Input ingredients
tablets,capsules,powders,films,miniaturized compressed pellets,drug candidates,nanoparticles
Output ingredients
solubility profiles,intrinsic dissolution rate,dissolution profiles,supersaturation patterns,precipitation patterns,dissolution rate data,kinetic solubility,nanoparticle solubility
Market info

Technical Specifications


Spatial Volume
2-20 ml
UV/VIS Spectra Range
200-720 nm
Spectrum Resolution
1nm
Data Collection Frequency
Every two seconds
Analysis Software
AuPRO™
Probe Material
Stainless Steel
Number of Spectrophotometers
Up to 8
Flexibility
Multiple experimental conditions on a single platform

Operating Characteristics


Real-time monitoring
Yes
Process type
Batch
Automation level
Automated with smart software
Data Collection Frequency
Every two seconds
Volume Range
2-20 mL
Dissolution Media
Aqueous and Non-Aqueous
Analysis Software
AuPRO™
Stirring Speed
Adjustable
Spectrophotometer type
Photo Diode Array
Wavelength Range
200–720 nm
Graphical Display
User-friendly
Probe Material
Stainless Steel

Material Compatibility


Stainless Steel Compatibility
Compatible
UV Stability
Stable

Product type Characteristics


Volume Range
2–20 mL
Dissolution Media
Aqueous and Non-Aqueous
Formulation Types
Tablets,Capsules,Powders,Films
Probes Material
Stainless Steel
Pathlength Tips
Interchangeable

Physical Characteristics


Probe material
Stainless steel
Volume range
2-20 mL
Data collection resolution
1 nm

Custom Options


Probe material
Stainless steel
Interchangeable pathlength tips
Yes
Control software
AuPRO™
Data collection frequency
Every two seconds
Spectrophotometer type
Photo Diode Array
Resolution
1nm
Volume range
2-20 ml
Software architecture
Flexible