Uv monitoring system for small volume dissolution studies
Efficiently monitor small-volume dissolution processes in real-time with UV spectrophotometry, ensuring precise data collection for comprehensive solubility and dissolution analysis.

Monitors and Analyzes Small Volume Drug Dissolution
The MicroDISS Profiler from Pion Inc. is an innovative UV monitoring system designed for small volume dissolution analysis in pharmaceutical and biotech environments. It utilizes dip-style probes made of stainless steel for durability and precise optical readings. Ideal for tablets, capsules, and powders, it excels in generating real-time dissolution profiles and handling complex solubility challenges. With its multi-channel capability, the system captures data at 1nm resolution across the UV/VIS spectrum every two seconds, ensuring comprehensive analysis of up to eight vessels simultaneously. The MicroDISS Profiler integrates seamlessly into R&D and laboratory settings, supporting a wide range of volumes and stirring speeds, offering a versatile solution for both aqueous and non-aqueous media analyses. Configurable pathlength tips enable cost-efficient adaptation to varying experimental needs, while its software platform provides robust data handling and visualization tools. The system is particularly suited for scenarios requiring detailed supersaturation and precipitation insight, supporting critical research on bioavailability and dissolution kinetics.
Benefits
- Enhances analytical accuracy with simultaneous real-time data collection.
- Increases efficiency in small volume dissolution testing for diverse formulations.
- Supports comprehensive solubility analysis, aiding in faster R&D cycles.
- Reduces operational costs with interchangeable pathlength tips for experimental flexibility.
- Facilitates complex dissolution profile studies, improving product development insights.
- Applications
- Drug formulations,Pharmaceutical tablets,Nanoparticles,Films,Powders,Excipients,Capsules,Salts
- End products
- Intrinsic dissolution rate profiles,Loratidine hot melt extrudates,Biorelevant dissolution profiles,Supersaturation and precipitation models,Self-emulsifying lipid-based formulations
- Steps before
- Intrinsic dissolution,Pre-formulation analysis,Miniaturized sample preparation,Polymorphic form screening,Nanoparticle preparation
- Steps after
- Data analysis,Results evaluation,Bioavailability testing,Distribution phase analysis
- Input ingredients
- tablets,capsules,powders,films,miniaturized compressed pellets,drug candidates,nanoparticles
- Output ingredients
- solubility profiles,intrinsic dissolution rate,dissolution profiles,supersaturation patterns,precipitation patterns,dissolution rate data,kinetic solubility,nanoparticle solubility
- Market info
- Spatial Volume
- 2-20 ml
- UV/VIS Spectra Range
- 200-720 nm
- Spectrum Resolution
- 1nm
- Data Collection Frequency
- Every two seconds
- Analysis Software
- AuPRO™
- Probe Material
- Stainless Steel
- Number of Spectrophotometers
- Up to 8
- Flexibility
- Multiple experimental conditions on a single platform
- Real-time monitoring
- Yes
- Process type
- Batch
- Automation level
- Automated with smart software
- Data Collection Frequency
- Every two seconds
- Volume Range
- 2-20 mL
- Dissolution Media
- Aqueous and Non-Aqueous
- Analysis Software
- AuPRO™
- Stirring Speed
- Adjustable
- Spectrophotometer type
- Photo Diode Array
- Wavelength Range
- 200–720 nm
- Graphical Display
- User-friendly
- Probe Material
- Stainless Steel
- Stainless Steel Compatibility
- Compatible
- UV Stability
- Stable
- Volume Range
- 2–20 mL
- Dissolution Media
- Aqueous and Non-Aqueous
- Formulation Types
- Tablets,Capsules,Powders,Films
- Probes Material
- Stainless Steel
- Pathlength Tips
- Interchangeable
- Probe material
- Stainless steel
- Volume range
- 2-20 mL
- Data collection resolution
- 1 nm
- Probe material
- Stainless steel
- Interchangeable pathlength tips
- Yes
- Control software
- AuPRO™
- Data collection frequency
- Every two seconds
- Spectrophotometer type
- Photo Diode Array
- Resolution
- 1nm
- Volume range
- 2-20 ml
- Software architecture
- Flexible