Pharmaceutical freeze dryer for large-scale production
Streamline your freeze-drying process with precision-engineered lyophilization technology that ensures maximum product stability and quality retention, ideal for producing delicate formulations like vaccines and enzymes.

Performs Efficient Freeze Drying and Lyophilization
The SMART LYO® Pharma Freeze Dryer from GEA utilizes proven, standardized modules to deliver precise and efficient lyophilization for pharmaceuticals and biopharmaceuticals. This equipment excels in maintaining the integrity of sensitive products such as vaccines, antibiotics, and monoclonal antibodies through its advanced vacuum drying and refrigeration processes. With shelf sizes ranging from 6.7 to 41.2 m² and a condenser capacity of up to 800 kg, it’s designed to accommodate diverse production needs. The system operates automatically in batch mode and integrates seamlessly into processing and final conditioning departments, reducing costs while meeting strict regulatory standards like cGMP and FDA. Its single-floor plant frame allows for rapid commissioning, and it’s compatible with the ALUS® system for automatic loading and unloading. The remote refrigeration unit installation adapts to various facility layouts, ensuring flexibility. Backed by the GEA Global Service Network, it offers quick access to spare parts and comprehensive maintenance, minimizing downtime and optimizing production efficiency.
Benefits
- Accelerates time-to-market with reduced delivery and validation times.
- Ensures consistent product quality for sensitive pharmaceuticals like vaccines and hormones.
- Minimizes installation complexity with a single-floor plant frame setup.
- Enhances operational flexibility through remote refrigeration unit placement.
- Complies with stringent regulatory standards, ensuring industry compliance.
- Applications
- Vitamins,Liquid formulations,Fine chemicals,Nutraceuticals,Pharmaceutical powder,Biopharmaceuticals,Pharmaceuticals
- End products
- Protein powders,Vaccines,Vitamin c,Insulin,Monoclonal antibodies,Antibiotics,Probiotic capsules,Enzyme solutions,Omega-3 supplements,Hormones
- Steps before
- Formulation,Filling in Vials,Pre-Cooling
- Steps after
- Sterilization,Packaging,Inspection,Labeling
- Input ingredients
- pharmaceutical solutions,vials,bulk materials,formulations
- Output ingredients
- lyophilized pharmaceutical products,freeze-dried vials,stabilized formulations
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.
- Condenser capacity
- 100–800 kg/24h
- Shelf area
- 6.7–41.2 m²
- Shelf temperature
- -55 to +70°C
- Condenser temperature
- -75°C
- Shelf size
- 914 x 1219 mm to 1524 x 1803 mm
- Unit dimensions
- Length
- No. of vials (Ø 16mm)
- 29,496–182,865
- No. of vials (Ø 22mm)
- 15,498–96,585
- No. of vials (Ø 30mm)
- 8,142–51,750
- No. of shelves
- 6 to 15
- Clearance
- 120 mm
- Weight
- 7.5 to 19 t
- Frame mounting
- Single-floor plant frame
- Batch vs. continuous operation
- Batch
- CIP/SIP
- CIP / SIP compatible
- Automation level
- PLC-compatible
- Energy efficiency
- Specific to freeze drying processes
- Frame mounting
- Single-floor plant frame
- Installation adaptability
- Remote refrigeration unit installation
- Loading/Unloading system compatibility
- ALUS® Automatic System
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine Footprint
- Length
- Condenser Capacity
- 100-800 kg/24h
- Shelf Area
- 6.7-41.2 m²
- Refrigeration Unit Installation
- Can be installed remotely from the plant frame,on a different floor
- Shelf Size
- 914 x 1219 mm to 1524 x 1803 mm
- Shelf Temperature Range
- -55°C to +70°C
- Number of Shelves
- 6 + 1 to 15 + 1
- Condenser Temperature
- -75°C
- Single-Floor Plant Frame
- Yes,for fast,simple commissioning
- Single-floor plant frame
- Yes
- Frame mounting installation
- Facilitated installation