Vacuum paddle dryer for active pharmaceutical ingredients

For precise moisture control and contamination-free conditions, this system ensures effective drying of sensitive compounds while maintaining high product integrity, essential before final formulation in various applications.

Dries and Discharges Sensitive Solid Products

The MAVAPAD® Vacuum Paddle Dryer from GMM Pfaudler offers a robust solution for efficient drying in pharmaceutical, chemical, and food industries. Featuring a large heat transfer area with flat ends, it ensures faster drying and lower heel volumes for challenging applications like APIs and specialty chemicals. The system’s hollow rotating agitator improves heat transfer, and its fully openable door facilitates thorough cleaning and validation. Designed with a choice of stainless steel, Hastelloy, or special alloys, it handles corrosive environments efficiently. The equipment complies with cGMP and FDA guidelines, providing reliable performance in sterile settings. Integration is seamless, utilizing the Dry9000® shaft sealing system to prevent contamination. Optional features like a lump breaker and sampling systems enhance functionality, while the twist close valve ensures quick, residue-free discharge. Tailored engineering support ensures that MAVAPAD® meets specific process needs, promoting operational efficiencies across batch and manual operations.

Benefits

  • Enhances drying efficiency with large heat transfer area, reducing processing time.
  • Minimizes contamination risk with advanced Dry9000® shaft sealing system.
  • Lowers maintenance costs through a design focused on easy cleaning and inspection.
  • Ensures regulatory compliance with cGMP and FDA standards.
  • Offers material flexibility for handling corrosive products, supporting various industrial applications.

General


Applications
Active pharmaceutical ingredients,Chemical products,Energy sector products,Corrosion-resistant solutions,Pharmaceutical products,Food products,Pure chemistry
End products
Cosmetic intermediates,Paracetamol,Aspirin,Biofuels,Specialty chemicals,Vitamin c,Food flavorings,Nutraceutical supplements,Specialty coatings,Catalysts,Food preservatives,Ibuprofen
Steps before
Filtration,Separation,Extraction
Steps after
Dust Filtration,Sampling,Vacuum Packaging
Input ingredients
Active Pharmaceutical Ingredients (APIs),chemistry applications,material for drying
Output ingredients
dried Active Pharmaceutical Ingredients (APIs),dried products,dried chemistry materials
Market info
GMM Pfaudler is known for manufacturing glass-lined equipment, reactors, and engineered-to-order (ETO) solutions for the chemical, pharmaceutical, and allied industries, recognized for their innovation, quality, and global presence.

Technical Specifications


Heat Transfer Area
Large (vessel body and agitator)
Door Opening
Full door opening for easy cleaning
Base Material
Stainless steel,Hastelloy,special alloys
Shaft Sealing Design
Interseal Dry9000® system
Agitator Design
Hollow rotating agitator with improved paddle design
Discharge Valve
Twist close valve/Segmented ball valve
Compliance
cGMP and FDA guidelines
Drying Time
Optimized for faster drying
Operating Costs
Lower compared to other dryers
Partition Wall
Stainless-steel for sterile/clean room areas

Operating Characteristics


Working mechanism
Vacuum paddle drying
Process compatibility
cGMP and FDA compliance
Cleaning and validation
Full door opening
Batch vs. continuous operation
Batch
Material options
Stainless steel,Hastelloy,special alloys
Energy efficiency
Lower operating costs
Automation level
Manual / PLC options
Changeover time
Quick discharge with twist close valve

Material Compatibility


Stainless Steel
AISI 316L,AISI 304
Corrosive resistance (e.g. acids)
Yes,compatible with Hastelloy
Special alloys
Available
Biological compatibility
cGMP compliant
Cleanability
Designed for Cleanroom use

Physical Characteristics


Vessel shape
Cylindrical with flat ends
Discharge method
Bottom discharge with twist close valve/segmented ball valve
Material options
Stainless steel,Hastelloy,special alloys
Agitator type
Hollow rotating agitator
Door type
Full door opening
Heat transfer area
Large (vessel body and agitator)

Custom Options


Material used
Stainless Steel / Hastelloy / Special Alloys
Shaft Sealing Design
Interseal Dry9000® / Double wet mechanical seal / Dry mechanical seal
Agitator Design
Hollow rotating agitator with improved paddle design
Discharge Method
Twist close valve / Segmented ball valve
Optional Accessories
Lump breaker,Sampling system,Condenser,Receiver,Vacuum pump