Vacuum paddle dryer for active pharmaceutical ingredients
For precise moisture control and contamination-free conditions, this system ensures effective drying of sensitive compounds while maintaining high product integrity, essential before final formulation in various applications.

Dries and Discharges Sensitive Solid Products
The MAVAPAD® Vacuum Paddle Dryer from GMM Pfaudler offers a robust solution for efficient drying in pharmaceutical, chemical, and food industries. Featuring a large heat transfer area with flat ends, it ensures faster drying and lower heel volumes for challenging applications like APIs and specialty chemicals. The system’s hollow rotating agitator improves heat transfer, and its fully openable door facilitates thorough cleaning and validation. Designed with a choice of stainless steel, Hastelloy, or special alloys, it handles corrosive environments efficiently. The equipment complies with cGMP and FDA guidelines, providing reliable performance in sterile settings. Integration is seamless, utilizing the Dry9000® shaft sealing system to prevent contamination. Optional features like a lump breaker and sampling systems enhance functionality, while the twist close valve ensures quick, residue-free discharge. Tailored engineering support ensures that MAVAPAD® meets specific process needs, promoting operational efficiencies across batch and manual operations.
Benefits
- Enhances drying efficiency with large heat transfer area, reducing processing time.
- Minimizes contamination risk with advanced Dry9000® shaft sealing system.
- Lowers maintenance costs through a design focused on easy cleaning and inspection.
- Ensures regulatory compliance with cGMP and FDA standards.
- Offers material flexibility for handling corrosive products, supporting various industrial applications.
- Applications
- Active pharmaceutical ingredients,Chemical products,Energy sector products,Corrosion-resistant solutions,Pharmaceutical products,Food products,Pure chemistry
- End products
- Cosmetic intermediates,Paracetamol,Aspirin,Biofuels,Specialty chemicals,Vitamin c,Food flavorings,Nutraceutical supplements,Specialty coatings,Catalysts,Food preservatives,Ibuprofen
- Steps before
- Filtration,Separation,Extraction
- Steps after
- Dust Filtration,Sampling,Vacuum Packaging
- Input ingredients
- Active Pharmaceutical Ingredients (APIs),chemistry applications,material for drying
- Output ingredients
- dried Active Pharmaceutical Ingredients (APIs),dried products,dried chemistry materials
- Market info
- GMM Pfaudler is known for manufacturing glass-lined equipment, reactors, and engineered-to-order (ETO) solutions for the chemical, pharmaceutical, and allied industries, recognized for their innovation, quality, and global presence.
- Heat Transfer Area
- Large (vessel body and agitator)
- Door Opening
- Full door opening for easy cleaning
- Base Material
- Stainless steel,Hastelloy,special alloys
- Shaft Sealing Design
- Interseal Dry9000® system
- Agitator Design
- Hollow rotating agitator with improved paddle design
- Discharge Valve
- Twist close valve/Segmented ball valve
- Compliance
- cGMP and FDA guidelines
- Drying Time
- Optimized for faster drying
- Operating Costs
- Lower compared to other dryers
- Partition Wall
- Stainless-steel for sterile/clean room areas
- Working mechanism
- Vacuum paddle drying
- Process compatibility
- cGMP and FDA compliance
- Cleaning and validation
- Full door opening
- Batch vs. continuous operation
- Batch
- Material options
- Stainless steel,Hastelloy,special alloys
- Energy efficiency
- Lower operating costs
- Automation level
- Manual / PLC options
- Changeover time
- Quick discharge with twist close valve
- Stainless Steel
- AISI 316L,AISI 304
- Corrosive resistance (e.g. acids)
- Yes,compatible with Hastelloy
- Special alloys
- Available
- Biological compatibility
- cGMP compliant
- Cleanability
- Designed for Cleanroom use
- Vessel shape
- Cylindrical with flat ends
- Discharge method
- Bottom discharge with twist close valve/segmented ball valve
- Material options
- Stainless steel,Hastelloy,special alloys
- Agitator type
- Hollow rotating agitator
- Door type
- Full door opening
- Heat transfer area
- Large (vessel body and agitator)
- Material used
- Stainless Steel / Hastelloy / Special Alloys
- Shaft Sealing Design
- Interseal Dry9000® / Double wet mechanical seal / Dry mechanical seal
- Agitator Design
- Hollow rotating agitator with improved paddle design
- Discharge Method
- Twist close valve / Segmented ball valve
- Optional Accessories
- Lump breaker,Sampling system,Condenser,Receiver,Vacuum pump