Wet granulation for pharmaceutical products
Achieve seamless integration of sifting and milling with precise powder handling to enhance product consistency and throughput in pharmaceutical production.

Sifts and Mills Pharmaceutical Powders Efficiently
The SigmaCombo from SSPM Systems & Engineers is a versatile sifting and milling solution tailored for pharmaceutical manufacturers. This sophisticated system combines a pneumatic conveying mechanism for seamless material transfer between processes, supervised through a user-friendly PLC-based interface. Capable of processing up to 250 kg/hour, it integrates into existing production lines to efficiently handle pharmaceutical powders and granules destined for end-products such as paracetamol tablets and multivitamin capsules. It complies with GMP, FDA, and MHRA standards, ensuring regulatory acceptance across various industries including biotech and chemical sectors. Constructed with robust SS 316 contact parts, it offers durability and corrosion resistance. With features like interchangeable sieves and impeller swapping, it facilitates quick adjustments to meet specific processing needs, thereby enhancing throughput and operational flexibility.
Benefits
- Increases production efficiency by streamlining powder processing stages.
- Ensures particle size uniformity, enhancing product quality and consistency.
- Reduces manual intervention and labor costs with automated PLC control.
- Facilitates rapid cleaning and maintenance, minimizing operational downtime.
- Adapts to various material types with flexible sieve and impeller options.
- Applications
- Supplements,Fine chemicals,Pharmaceutical tablets,Nutraceuticals,Pharmaceutical powder
- End products
- Ibuprofen tablets,L-ascorbic acid powder,Multivitamin capsules,Vitamin c tablets,Herbal supplements,Protein powder,Calcium tablets,Omega-3 capsules,Paracetamol tablets,Coenzyme q10 supplements
- Steps before
- Purification,Drying
- Steps after
- Blending,Packing,Coating,Tablet Pressing
- Input ingredients
- pharmaceutical materials,raw materials for sifting,materials for milling
- Output ingredients
- sifted particles,milled particles,blended materials
- Market info
- Output
- 250 Kg/Hr
- Connecting Loads
- 13 HP
- Sifter Sieves Size
- Options Are Available
- Co-Mill Sieves Size
- Options Are Available
- Contact Parts Material
- SS 316
- Non-contact Parts Material
- SS 304
- Automation
- PLC-based control system
- Conveying System
- Pneumatic conveying system
- Operation Controls
- PLC,color touch screen,manual push-button control
- Working mechanism
- Sifting,Milling,Conveying,Blending
- Integrated steps
- Sifting cum Milling
- Automation level
- PLC-based control system
- CIP/SIP
- Easy cleaning
- Batch vs. continuous operation
- Batch
- Cleaning method
- Easy cleaning
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Particle size variation
- Sieve options available
- GMP compliance
- Yes
- FDA compliance
- Yes
- MHRA compliance
- Yes
- PICS compliance
- Yes
- Control panel type
- PLC,colour touch screen,or manual push-button control
- Discharge method
- Pneumatic conveying system to blender bin
- Detachable components
- Sieves and sifters
- Material
- Contact Parts SS 316,Non Contact Parts SS 304
- Output capacity
- 250 Kg/Hr
- Connecting Load
- 13 HP
- Customizable sieve sizes
- Options Are Available
- Control panel type
- PLC / Colour touch screen / Manual push-button
- Integration possibilities
- Pneumatic conveying system / Sifter and miller combo
- Sieve and impeller options
- Detachable sieves / Impeller swapping