Wet granulation for pharmaceutical products

Achieve seamless integration of sifting and milling with precise powder handling to enhance product consistency and throughput in pharmaceutical production.

Sifts and Mills Pharmaceutical Powders Efficiently

The SigmaCombo from SSPM Systems & Engineers is a versatile sifting and milling solution tailored for pharmaceutical manufacturers. This sophisticated system combines a pneumatic conveying mechanism for seamless material transfer between processes, supervised through a user-friendly PLC-based interface. Capable of processing up to 250 kg/hour, it integrates into existing production lines to efficiently handle pharmaceutical powders and granules destined for end-products such as paracetamol tablets and multivitamin capsules. It complies with GMP, FDA, and MHRA standards, ensuring regulatory acceptance across various industries including biotech and chemical sectors. Constructed with robust SS 316 contact parts, it offers durability and corrosion resistance. With features like interchangeable sieves and impeller swapping, it facilitates quick adjustments to meet specific processing needs, thereby enhancing throughput and operational flexibility.

Benefits

  • Increases production efficiency by streamlining powder processing stages.
  • Ensures particle size uniformity, enhancing product quality and consistency.
  • Reduces manual intervention and labor costs with automated PLC control.
  • Facilitates rapid cleaning and maintenance, minimizing operational downtime.
  • Adapts to various material types with flexible sieve and impeller options.

General


Applications
Supplements,Fine chemicals,Pharmaceutical tablets,Nutraceuticals,Pharmaceutical powder
End products
Ibuprofen tablets,L-ascorbic acid powder,Multivitamin capsules,Vitamin c tablets,Herbal supplements,Protein powder,Calcium tablets,Omega-3 capsules,Paracetamol tablets,Coenzyme q10 supplements
Steps before
Purification,Drying
Steps after
Blending,Packing,Coating,Tablet Pressing
Input ingredients
pharmaceutical materials,raw materials for sifting,materials for milling
Output ingredients
sifted particles,milled particles,blended materials
Market info

Technical Specifications


Output
250 Kg/Hr
Connecting Loads
13 HP
Sifter Sieves Size
Options Are Available
Co-Mill Sieves Size
Options Are Available
Contact Parts Material
SS 316
Non-contact Parts Material
SS 304
Automation
PLC-based control system
Conveying System
Pneumatic conveying system
Operation Controls
PLC,color touch screen,manual push-button control

Operating Characteristics


Working mechanism
Sifting,Milling,Conveying,Blending
Integrated steps
Sifting cum Milling
Automation level
PLC-based control system
CIP/SIP
Easy cleaning
Batch vs. continuous operation
Batch
Cleaning method
Easy cleaning

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Particle size variation
Sieve options available


GMP compliance
Yes
FDA compliance
Yes
MHRA compliance
Yes
PICS compliance
Yes

Physical Characteristics


Control panel type
PLC,colour touch screen,or manual push-button control
Discharge method
Pneumatic conveying system to blender bin
Detachable components
Sieves and sifters
Material
Contact Parts SS 316,Non Contact Parts SS 304
Output capacity
250 Kg/Hr
Connecting Load
13 HP
Customizable sieve sizes
Options Are Available

Custom Options


Control panel type
PLC / Colour touch screen / Manual push-button
Integration possibilities
Pneumatic conveying system / Sifter and miller combo
Sieve and impeller options
Detachable sieves / Impeller swapping