Continuous granulation and drying system for pharma production
Achieve precise control over granule quality with a continuous solution that enhances production efficiency, ensuring high standards for pharmaceutical tablets and granules.
Processes and Dries Pharmaceutical Granules Continuously
The ConsiGma® Granulation and Drying Modules from GEA offer a continuous twin-screw granulation and drying solution that delivers exceptional granule quality for pharmaceutical applications. Utilizing a standalone continuous process, it ensures precise granulation control, enhancing the consistency of tablets, powders, and granules. With processing capacities ranging from 5 to 120 kg/h, these modules integrate into existing bin-2-bin setups and can be customized with various options to meet specific needs. The Conductor 4.0 software ensures seamless operation, integrating with upstream and downstream equipment. Available with options like solvent processing compatibility and Pressure Shock Resistant design, the modules are also designed for minimal at-risk API, adhering to SUPAC guidelines. Suitable for a range of pharmaceuticals, including extended-release and effervescent tablets, these modules facilitate controlled drying and granulation, enhancing throughput and product quality while meeting GMP standards.
Benefits
- Maximizes product consistency with precise granulation control.
- Enhances operational efficiency through continuous processing.
- Integrates seamlessly into existing setups for minimal disruption.
- Reduces material waste with controlled at-risk API levels.
- Meets strict pharmaceutical standards for GMP compliance.
- Applications
- Granules,Powder processing,Pharmaceutical tablets,Pharmaceuticals
- End products
- Active ingredient powders,Pharmaceutical pills,Vitamin tablets,Oral granules,Active pharmaceutical ingredient (api) granules,Solvent-free granules,Effervescent tablets,Nutraceutical tablets,Extended release tablets
- Steps before
- Mixing,Weighing
- Steps after
- Tablet Coating,Tablet Compression,Blending,Packing
- Input ingredients
- pre-mix,active pharmaceutical ingredients (API),feed material,binders,solvents
- Output ingredients
- granules,dry granules,conditioned granules,tablet cores
- Market info
- GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.
- Granulation Type
- Twin-screw granulation
- Throughput
- 5–120 kg/h
- Drying Module
- Segmented fluid bed dryer
- Control System
- Conductor 4.0 software
- Automation
- PLC-controlled
- Material Handling System
- Including containment features
- Feeder Type
- Loss-in-weight feeder
- Pressure Shock Resistant Design
- Available
- Solvent Processing
- Suitable
- Particle Size Distribution Control
- Yes
- API Content Flexibility
- Very low to very high
- Porosity Control
- Yes
- Working mechanism
- Twin-screw granulation
- Process type
- Continuous
- Automation level
- Conductor 4.0 Software
- Integrated steps
- Granulation and Drying
- Batch vs. continuous operation
- Bin-to-bin continuous
- Control system
- PLC
- Material handling
- With containment features
- Customization Options
- Variable throughput capacities
- Level of process control
- Seamless with full reporting
- Solvent compatibility
- Suitable for Solvents processing
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Corrosive resistance
- Pressure Shock Resistant (PSR) design
- GMP Compliance
- Yes
- Discharge method
- Bin-2-bin
- HMI type
- Conductor 4.0 software
- Integration possibilities
- Handshaking with up- or downstream equipment
- Choice of feeder
- GEA or qualified third-party feeder
- Pressure Shock Resistant design
- Suitable for Solvents processing
- Optional Lighthouse Probe
- For LOD measurement