Roller compaction for dry granulation in pharmaceuticals
In pharmaceutical manufacturing, precise control of particle size and density is essential for creating high-quality granules. Conventional wet granulation processes might not be suitable for moisture-sensitive materials, necessitating advanced dry granulation techniques.
High containment dry granulation with roller compaction
The CCS Roller Compaction Series by The Fitzpatrick Company offers a robust solution for dry granulation across various scales of pharmaceutical production. This system is designed for high containment applications and features a unique dual-screw feed system that creates ideal conditions at the nip area of the rolls, ensuring consistent and high-quality results. Models in this series range from R&D focused units to large-scale production systems, all featuring the same basic design for easy scalability and maintenance. The roller units are vacuum-tight and can be equipped with a patented Product Containment System (PCS) for even higher containment levels, with the added option of nitrogen inerting and security interlock. The CCS models are suitable for pharmaceutical, nutraceutical, food, and fine chemical applications, all within a system that maximizes production uptime and minimizes maintenance efforts. Capacity ranges from 25kg/hr on the smallest model to 400kg/hr on the largest, with options for wash-in-place capabilities and customizable configurations.
Benefits
- Scalable from R&D to large production
- High containment with optional PCS system
- Reduced maintenance with few components
- Uniform results due to dual-screw feed system
- Flexible configurations to suit specific needs