Roller compaction for dry granulation in pharmaceuticals
Ensure consistent granule size and density in your product line with high containment roller compaction, ideal for precise dry granulation and easy scaling from research to full production.
Performs High Containment Dry Granulation
The CCS series from Fitzpatrick offers a range of roller compactors designed for precision dry granulation. Engineered for pharmaceutical and chemical manufacturing, these units provide high containment and seamless scalability from R&D to large production. The dual-screw feed system ensures optimal material conditions for efficient compaction, while the patented Product Containment System enhances safety with nitrogen inerting. The models, including the CCS220, CCS320, CCS520, CCS720, and CCS1025, boast flexible installation options such as in-wall and through-wall, optimizing space in GMP facilities. Capable of producing up to 400 kg/hr, these compactors integrate seamlessly with existing systems, with standardized HMIs for intuitive operation. Designed with minimal components, they facilitate easy maintenance and cleaning, offering optional wash-in-place capabilities. Fitzpatrick’s equipment complies with stringent industry standards, featuring ATEX-approved variants for explosive environments, and supports a variety of materials like stainless steel for enhanced corrosion resistance.
Benefits
- Enhances product safety with high containment and nitrogen inerting, crucial for sensitive applications.
- Offers scalability from lab to production, enabling seamless transitions as production demands grow.
- Minimizes maintenance costs with durable design and shared components across models.
- Supports flexible facility layouts with in-wall and through-wall installation options.
- Reduces cleaning time and cross-contamination risk with wash-in-place capability.
- Applications
- Supplements,Pharmaceutical tablets,Fine chemicals,Pharmaceutical formulation,Nutraceutical formulation,Food processing
- End products
- Protein powders,Herbal extract granules,Instant soup mixes,Detergent additives,Vitamin supplements,Food seasoning mixes,Chemical catalysts,Effervescent tablets
- Steps before
- Material Preparation,Pre-Blending
- Steps after
- Tablet Pressing,Capsule Filling,Coating,Packaging
- Input ingredients
- powder materials,pharmaceutical powders,nutraceutical powders,food powders,chemical powders
- Output ingredients
- granules,compacted products,pharmaceutical granules,nutraceutical granules,food granules,chemical granules
- Market info
- The Fitzpatrick Company is known for its expertise in designing and manufacturing particle processing equipment, specializing in dry granulation, roll compaction, and size reduction technologies, earning a strong reputation for quality and innovation in the pharmaceutical and industrial sectors.
- Roll Force
- 17–26 kN/cm
- Roll Dimensions
- 2 X 20 cm to 10 X 25 cm
- Roll Gap
- 1-6 mm
- Capacity
- Up to 400 kg/hr
- Model-specific options
- Isolator-ready,Laminar flow booth arrangement,Wash-in-place capabilities
- Installation design
- Freestanding or Through-wall
- Product Containment System
- Available
- Automation
- Standardized HMI screens
- Scalability
- Directly scalable from lab to production units
- Working mechanism
- Dual-screw feed system
- Integrated steps
- Dry granulation and compaction
- Batch vs. continuous operation
- Batch / Inline Continuous
- Automation level
- PLC-controlled
- Changeover time
- Minimal due to standardized design
- CIP/SIP
- Wash-in-place capabilities
- Cleaning method
- Wash-in-place / Manual
- Containment level
- High containment with PCS
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Agglomeration risk
- Minimized
- Roll Dimensions
- 2 X 20 cm,3 X 20 cm,5 X 20 cm,7.5 X 20 cm,10 X 25 cm
- Roll Gap
- 1-6 mm
- Roll Force
- 17-26 kN/cm
- Compact Footprint
- Mobile units,convertible designs
- Installation Type
- Free-standing,In-wall,Through-wall
- Containment System
- Product Containment System (PCS) with nitrogen inerting
- Wash-in-Place Capabilities
- Available
- Machine Design
- Standardized HMI screens
- Wash-in-place Capabilities
- Yes
- Product Containment System (PCS)
- Nitrogen inerting and security interlock
- Compact,Mobile Unit
- Easily movable