Lab scale mixer, extruder & spheronizer for r&d formulation
Optimize and streamline your research and development process with a versatile system that handles mixing, granulation, extrusion, and spheronization, minimizing material waste while accelerating formulation trials.
Mixes, Granulates, Extrudes, and Spheronizes Small Batches
The Caleva Multi Lab is an integrated lab-scale solution for pharmaceutical and chemical process development. Capable of mixing, granulating, extruding, and spheronizing within a compact footprint, it serves research and development labs, universities, and manufacturers needing efficient small-batch processing. The equipment excels in reducing development time, supporting batch sizes from 10g to 50g, allowing you to experiment with minimal waste. Its variable density extrusion capability lets you fine-tune product characteristics like hardness and porosity, enhancing your formulation outcomes.
Ideal for applications including pharmaceutical pills, supplements, and enzyme tablets, the Caleva Multi Lab handles a variety of product types ranging from solids and powders to granules and slurries. It comes with specialized dies and mixing systems tailored for different viscosities and product requirements. The equipment’s design facilitates fast setup and cleaning, crucial for iterative R&D tasks. Moreover, the Caleva Multi Lab supports future scale-up with a range of extruders and optional attachments. The system’s compatibility with a wide array of materials and configurations ensures compliance with industry standards, while its engineering support provides tailored solutions to meet your precise needs.
Benefits
- Reduces development time by up to 50% with rapid component disassembly and cleaning.
- Minimizes material waste by enabling trials with batch sizes as small as 10g.
- Enhances formulation success through variable density extrusion for tailored product characteristics.
- Space-efficient design reduces laboratory footprint by 75% compared to similar equipment.
- Compliant with industry standards, ensuring reliability for pharmaceutical and chemical applications.
- Applications
- Supplements,Fine chemicals,Pharmaceutical tablets,Nutraceuticals,Pharmaceutical powder,Powder/liquid combinations,Biopharmaceuticals,Enzymes,Catalysts
- End products
- Biopharmaceutical drugs,Nutritional supplements,Pharmaceutical pills,Effervescent tablets,Nutrient capsules,Enzyme tablets,Chemical catalysts,Pharmaceutical granules
- Steps before
- Material Preparation,Weighing,Purification,Pre-mixing
- Steps after
- Coating,Drying,Tablet Forming,Packaging
- Input ingredients
- powders,creams,pastes,gels,powder/liquid combinations,highly viscous materials,small quantities of catalytic material
- Output ingredients
- pellets,extrudates
- Market info
- Caleva Process Solutions is known for manufacturing and supplying specialized equipment for pellet and extrudate production in the pharmaceutical, nutraceutical, chemical, and food industries, emphasizing innovative process solutions and customer-focused engineering.
- Capacity
- 10g to 50g (formulation dependent)
- Automation
- Quick disassembly and easy cleaning
- Batch size
- 10g to 50g (formulation dependent)
- Size
- Small footprint
- Mixing bowl volume
- 71ml (half-size) or 275ml (full-size)
- Die Options
- Standard and High Density
- Extrusion dies available
- Variety of hole sizes and configurations
- Mixing type
- Contra-rotating blades
- Screw type
- Two different extruder screws
- Viscosity handling
- Sigma blade for high viscosity
- Die hole diameter
- 0.5 mm to 3.0 mm in 0.1 mm increments
- Density Modification
- Variable Density Capability
- Water Jacket Option
- Available for both full-size and half-size bowls
- Working mechanism
- Mix,Granulate,Extrude,Spheronize
- Batch processing
- 10g to 50g
- Integration of processes
- 3 processes on a single base unit
- Manual vs automated
- Quick disassembly,easy to clean
- Footprint size
- Very Small Footprint
- Variable density control
- Modify extrudate density,hardness,friability,and porosity
- Flexibility of configurations
- Multiple configurations per process
- Cooling option
- Water jacketed bowl
- Changeover time
- Fast turnaround speed
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- ISO 9001 Certification
- Yes
- GMP Compliance
- Potentially applicable
- FDA Compliance
- Possibly relevant for materials
- Machine footprint
- Remarkably small
- Batch size
- 10–50 g (formulation dependent)
- Mixing bowl size
- Full-size
- Half-size
- 71 ml
- Base unit
- Single,small
- Spheronizer disc pattern
- Multiple patterns available
- Extruder die size
- 0.5 mm to 3.0 mm in 0.1 mm increments
- Die configuration
- Standard and high density
- Spheronization disc patterns
- Multiple patterns available
- Mixing bowl size
- Standard and half-size
- Mixing bowl water jacket
- Optional availability
- Extruder screw types
- Two different screws
- Blade configurations
- Standard,Sigma blade systems
- Die hole designs
- Circular,trilobe,quadrilobe
- Cooling/heating option
- Water jacketed bowl