In-situ fiber optic Uv-vis spectrometer for dissolution studies
Optimize drug formulation by obtaining real-time, in-situ UV-Vis measurements for dissolution and absorption processes, enhancing data accuracy while reducing analysis time.
Measures Real-Time Drug Dissolution and Absorption
The Rainbow R6 from Pion is an in-situ UV-Vis spectrometer designed specifically for pharmaceutical, biopharmaceutical, and nutraceutical applications. It stands out by providing real-time concentration measurements, eliminating delays between sampling and analysis, and delivering consistent results. Ideal for immediate and controlled release tablets, injectable formulations, and dietary supplements, this equipment supports dissolution testing and solubility studies. The Rainbow R6 is compatible with small-scale dissolution testers for precise monitoring and features automated, bench-top operation suited for R&D and laboratory environments. Its software suite, including Pion Predictor and AuPRO, enhances data processing and analysis, ensuring compliance with industry standards.
Benefits
- Enhances formulation accuracy with real-time dissolution and absorption data.
- Streamlines R&D processes by eliminating sample processing delays.
- Facilitates early-stage drug development with minimal sample requirements.
- Optimizes dissolution rate testing for immediate release formulations.
- Integrates seamlessly into existing lab setups for efficient automation.
- Applications
- Biopharmaceuticals,Oral formulation delivery,Nutraceuticals,Pharmaceuticals
- End products
- Chewable tablets,Nutraceutical dietary supplements,Biopharmaceutical injectable formulations,Controlled release capsules,Solubility-enhanced drug formulations,Liquid oral suspensions,Effervescent tablets,Granules for oral solution,Dissolution rate-optimized drug products,Immediate release tablets
- Steps before
- Compound screening,Pre-formulation development,Sample preparation
- Steps after
- Data analysis,Quality control,Formulation development,Method development
- Input ingredients
- drug compounds,samples,dissolution media,flux apparatus samples
- Output ingredients
- dissolution rates,absorption data,flux measurements,concentration measurements,dissolution monitoring data,predicted fraction absorbed ratio
- Market info
- Sample measurement time
- Less than 5 seconds
- Measurement type
- In-Situ Fiber Optic UV-Vis
- Functionality
- Real-time concentration measurements
- Assay duration
- Extended,unattended assays
- Dissolution monitoring application
- MicroDISS,MiniDISS,MacroFLUX apparatus
- Automation level
- Manual / PLC / SCADA
- Batch vs. continuous operation
- Batch
- Cleaning method
- Manual
- Data collection speed
- Less than 5 seconds per sample
- In-situ measurement capability
- Yes
- Sample preparation requirement
- None
- Real-time data availability
- Yes
- Unattended operation capability
- Yes
- Biological compatibility
- Suitable for drug formulation and development
- Corrosive resistance (e.g. acids)
- Yes
- Cleanability
- CIP compatible
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Sample Limitation
- Low Sample Volume Required
- Biorelevant Testing
- MiniDISS,BioFLUX
- Control panel type
- HMI / Touchscreen
- Integration possibilities
- AUPro / DissoPRO / Pion Predictor
- Probe-based dissolution
- In-Situ UV
- Flexibility in sample size
- MicroFLUX / BioFLUX / MacroFLUX