Wet granulating equipment for pharmaceutical industry
Enhance production efficiency and safety in high-potency pharmaceutical manufacturing with advanced wet granulation technology, ensuring precise control over particle size and coating for optimal tablet formulation.
Granulates and Coats Pharmaceutical Powders and Pellets
AUSTAR’s Wet Granulating System, featuring high shear granulators and fluid bed processors, excels in precision pharmaceutical granulation and pellet coating. This system integrates process analytical technology (PAT) and automatic control systems ensuring consistent granule size and coating evenness for high-potency APIs and complex formulations. It caters to immediate and extended-release tablets, effervescent formulations, and enteric-coated pellets, handling both batch and continuous operations with high-speed processing capabilities.
Engineered for seamless integration within existing production lines, it supports batch management, electronic record-keeping, and data integrity in compliance with FDA, EMA, and WHO standards. Available in stainless steel, the equipment meets strict GMP and regulatory requirements, offering high corrosion resistance and robust material options. The modular design ensures easy cleaning and maintenance, supported by an experienced after-sales service team for ongoing operational efficiency and compliance verification. With customizable configurations and expert engineering support, the system ensures precise, high-quality production tailored to pharmaceutical and biotech needs.
Benefits
- Ensures high product quality with precise granule size and uniform coatings.
- Streamlines compliance with integrated data integrity and electronic record-keeping.
- Enhances production efficiency with high-speed batch and continuous operation modes.
- Minimizes risk of contamination with easy-to-clean design and robust material options.
- Supports high containment levels, achieving OEB3 to OEB5 for safe handling of potent compounds.
- Applications
- Pharmaceutical tablets,Pharmaceutical powder,Biopharmaceuticals,Pellet coating,High toxic/activity api production
- End products
- Biopharmaceutical granules,Enteric-coated pellets,Cytotoxic drug formulations,Immediate-release tablets,Oral granules,Coated micro-pellets,Extended-release tablets,Effervescent tablets,High-potency active pharmaceutical ingredients (hpapi) tablets
- Steps before
- Powder Handling,Containment,Batch Management
- Steps after
- Pellet Coating,Validation,High Containment Application,Electronic Record Verification
- Input ingredients
- powder,solid materials,active pharmaceutical ingredients (APIs)
- Output ingredients
- wet granules,pellets,coated pellets
- Market info
- Austar is known for specializing in the design and manufacture of engineered-to-order industrial equipment, particularly in the pharmaceutical and biotechnology sectors, offering solutions that focus on quality, innovation, and meeting specific customer requirements.
- Automation
- GAMP5 compliance
- Batch management
- Electronic record,electronic signature
- Data integrity compliance
- FDA,EMA,WHO
- Containment level
- OEB3 to OEB5
- Control system
- Computerized control system verification
- Process analysis technology (PAT)
- Integrated
- Automation level
- PLC / SCADA
- Batch vs. continuous operation
- Batch
- CIP/SIP
- CIP 121°C / SIP 135°C
- Cleaning method
- CIP / Manual
- Energy efficiency
- 0.5–2 kWh/kg moisture
- Batch management
- Electronic record,electronic signature
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Control panel type
- Computerized with audit trail
- HMI integration
- GAMP5-compliant automatic control system
- Integration possibilities
- PAT integration for intelligent granulation solutions
- Batch management
- Electronic record,electronic signature