Continuous direct compression line for pharmaceuticals
In pharmaceutical manufacturing, achieving a continuous, efficient, and high-quality tablet production process can be challenging, especially for generics, nutraceuticals, and OTC products. Traditional batch processing often results in higher work-in-progress and longer production times.
Seamlessly integrate dry blending and tablet compression
The GEA ConsiGma® Direct Compression with Ribbon Blending (DC-RB) Lines is an efficient solution that integrates continuous dry blending and tablet compression into a single production system. Available in three standard sizes, it offers throughputs ranging from 10 to 200 kg/h or 20,000 to 400,000 tablets/h. Featuring Conductor 4.0 software, it provides complete control over the entire process, including tracking of out-of-specification (OOS) material and material genealogy. The system includes 2 to 4 loss-in-weight feeders, a ribbon blender, and a GEA compression system. Customizable options like different feeders, blend uniformity measurement with Lighthouse Probe®, and containment material handling systems make it adaptable to various needs. Designed for easy blending and high-throughput direct compression formulations, it ensures higher blend homogeneity and increased material yield. The DC-RB lines are especially suited for generics, nutraceuticals, and OTC products, and offer a small footprint and flexible batch size.
Benefits
- Flexible batch size to meet varying production needs
- Eliminate work in progress through continuous processing
- Adaptable for blending fragile particles, ensuring homogeneity
- High yield with integrated in-process blend uniformity control
- Efficient, small footprint design for optimized space utilization