Continuous direct compression line for pharmaceuticals

Optimize tablet production with a seamless system combining continuous blending and compression, reducing footprint and improving yield efficiency.

Blends and Compresses Powders Continuously

The ConsiGma® Direct Compression with Ribbon Blending (DC-RB) Lines from GEA are designed to seamlessly integrate into your pharmaceutical or nutraceutical production line. These lines specialize in combining continuous dry blending and tablet compression, making them ideal for producing pharmaceutical tablets, multivitamin capsules, and various supplements. Available in three standard sizes, they offer throughput ranging from 10 to 200 kg/h or 20,000 to 400,000 tablets/hr, tailored to your production needs.

The system employs a ribbon blender to ensure uniform blending, followed by compression in one streamlined operation, significantly optimizing material yield and blend homogeneity. Featuring the Conductor 4.0 software, it provides thorough process control with continuous in-process blend uniformity measurement. This integration supports flexible batch sizes and variable throughput capacities without hold-up issues, adapting effortlessly to diverse product types from powders to granules.

The DC-RB lines are constructed with high corrosion resistance materials to comply with stringent GMP and FDA standards, ensuring quality and safety in pharmaceutical production. Enhanced by options like various feeder systems and containment features, the equipment supports customization for diverse production scenarios. Its compact design reduces the production footprint, eliminating work in progress and allowing for straightforward cleaning and maintenance, essential for maintaining operational efficiency and product integrity.

Benefits

  • Enhances production efficiency by integrating blending and compression into a continuous line.
  • Supports flexible manufacturing with adaptable batch sizes and high throughput capacity.
  • Ensures consistent product quality through in-process blend uniformity measurement.
  • Minimizes production space requirements with a compact system design.
  • Reduces operational costs and waste with high material yield and minimal work in progress.

General


Applications
Otc products,Nutraceuticals,Generic drugs,Pharmaceutical tablets
End products
Sleep aids,Allergy relief tablets,Multivitamin capsules,Generic pain relievers,Herbal supplements,Calcium supplements,Effervescent tablets,Omega-3 capsules,Probiotics
Steps before
Ingredient Weighing,Purification,Material Preparation
Steps after
Packing,Coating,Tablet Pressing,Sterilization
Input ingredients
easy-to-blend DC formulations,high-throughput DC formulations,fragile particles,API content,powder particles
Output ingredients
tablets,high blend homogeneity,higher material yield,in-process blend uniformity
Market info
GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.

Technical Specifications


Throughput Capacity
10 to 200 kg/h or 20,000 to 400,000 tablets/h
Batch Size
Flexible
Automation
Conductor 4.0 software
Blender type
Ribbon blender
Feeder options
2 to 4 loss-in-weight feeders
Material handling
Containment features included

Operating Characteristics


Batch vs. continuous operation
Continuous
Automation level
PLC with Conductor 4.0 software
Cleaning method
CIP Capable
Changeover time
Minimal due to integrated design
Energy efficiency
Optimized for continuous manufacturing

Material Compatibility


Cleanability
CIP/SIP capable
Corrosive resistance (e.g. acids)
Stainless steel construction

Product type Characteristics


Blending Method
Ribbon
Continuous Production
Yes
Compression Method
Direct Compression
Target Market
Generics / Nutraceuticals / OTC
Handling Type
Easy-to-blend / High-throughput

Physical Characteristics


Footprint
Compact for small footprint
System Size Options
Available in 3 standard sizes
Throughput Capacity
10 to 200 kg/h or 20,000 to 400,000 tablets/h
Integration Type
Continuous dry blending and tablet compression
Control System
Conductor 4.0 software
Feeder Types
2 to 4 loss-in-weight feeders
Blender Type
Ribbon blender

Custom Options


Control panel type
Conductor 4.0 software
Blender setup
Continuous flow or mini-batch
Feeder choice
GEA or qualified third-party supplier
Material handling system
Including containment features