Pharmaceutical fluid bed r&d processing

Ensure precise formulation and consistency in pharmaceutical and nutraceutical tablet production with advanced fluid bed processing, offering seamless integration for drying, granulation, and coating operations at the research and development scale.

Processes and Coats Pharmaceutical and Nutraceutical Tablets

The PharmaConnect® from GEA, equipped with the MP1 Flexstream technology, is a versatile fluid bed processor tailored for pharmaceutical R&D. It stands out with its capability to seamlessly integrate drying, granulation, and coating processes for a variety of applications such as antibiotic and dietary supplement tablet production. The system supports batch processing from 0.2 to 6 kg, offering flexibility in R&D settings.

PharmaConnect® utilizes a modular design, employing interchangeable components to achieve diverse processes like fluidization and pelletization, while maintaining stringent containment for handling potent compounds. The system features PLC control with process visualization to facilitate automation and precise control, enhancing its role in complex pharmaceutical environments.

Designed to comply with GMP and equipped with ATEX certification, the system ensures safe operation and meets international standards. Material options include stainless steel to prevent corrosion, ensuring a long lifespan. For ease of cleaning, the unit includes a blowback filter system and is configured for CIP operations, further simplifying maintenance and reducing downtime. GEA provides comprehensive engineering support to customize configurations, ensuring the equipment meets specific operational needs.

Benefits

  • Enhances production flexibility with modular components for diverse pharmaceutical processes.
  • Ensures operator safety and process integrity with fully contained handling systems.
  • Reduces maintenance time and costs with CIP-ready design.
  • Optimizes batch processing efficiency for R&D with scalable process capabilities.
  • Meets international safety standards with GMP compliance and ATEX certification.

General


Applications
Chemicals,Vitamins,Mini tablets,Fine chemicals,Pharmaceutical tablets,Nutraceuticals,Food stuffs,Dairy products,Pharmaceuticals
End products
Ibuprofen mini tablets,Lactose powders,Probiotic capsules,Antibiotic tablets,Dietary supplement tablets,Vitamin d3 powder,Protein granules,Effervescent tablets,Aspirin tablets
Steps before
Dispensing raw materials,Blending,High shear granulation
Steps after
Tablet pressing,Coating,Pelletization
Input ingredients
raw materials,fine powders,pellets,granules,crystals,mini tablets,binding agent,liquids for coating,organic solvents
Output ingredients
dried products,coated granules,tablets,agglomerates,spray granulated products,pelletized products
Market info
GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.

Technical Specifications


Air Flow range
2 m³/min
Airflow control
0.1–2 m/s
Automation
PLC-controlled
Batch size
0.2–6 kg
Batch vs. continuous
Batch
Coating method
Spray
Compressed Air Usage
6 barg
Container volume
0.8-16.5 L
Cycle temperature
65°C - 100°C

Operating Characteristics


Working mechanism
Fluid Bed Processing
Integrated steps
Drying,Granulation,Coating
CIP/SIP compatibility
CIP/WIP
Batch vs. continuous operation
Batch
Automation level
PLC Control
Containment level
OEB 5
Cleaning method
Manual / WIP
Changeover time
Rapid Changeover
Product transfer technology
Hicoflex System
Containment method
Intelligent Contained Handling Systems

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm


ATEX certification
Certified for use with organic solvents (explosion group IIA)
FDA compliance
FDA compliant materials for pharmaceutical use
GMP Compliance
Designed to meet GMP standards for pharmaceutical manufacturing

Physical Characteristics


Compact footprint
Table-top size
Control panel type
PLC/HMI Control System
Discharge method
Integrated Loading and Discharge Valves
Machine mobility
Mobile system
Size
0.2 to 6 kg capacity
Design
Through-the-Wall (TTW) Design
Weight
75 kg (STREA-1 Pro)
Dimensions (L x W x H)
1700 x 1000 x 2800 mm

Custom Options


Control panel type
OP/PLC Control
HMI Integration
Touch screen HMI
Process view software
ProcessView software
Recipe control
Automatic recipe control
Module interchangeability
Standard and Precision Modules
Product container material
Stainless Steel / Polycarbonate
Air distributor type
Special air distributor plate
Nozzle options
Two-fluid nozzle / Heated nozzle
Spray capability
Top or bottom spray
Filter material selection
Standard or Stainless Steel
Sampling device integration
Yes