Wet granulation co mill for pharmaceutical formulations

Optimize your manufacturing process with precise particle size reduction and mixing, ensuring uniform granules for enhanced bioavailability and product consistency in high-speed operations.

Reduces and Uniforms Particle Sizes

The Sigma Mill and Jumbo Co Mill from SSPM Systems & Engineers are engineered for superior particle size reduction and uniform granule production in pharmaceutical, nutraceutical, chemical, and food industries. These mills operate using a vacuum-rated top drive mechanism, allowing for high-speed operation with minimal fine generation. Ideal for producing tablets, capsules, and granules, they support batch and continuous operations with a throughput of 200 to 800 kg/hr, depending on the model. Designed in compliance with GMP and FDA standards, these mills ensure no contamination and maintain the integrity of granules. The robust yet compact construction includes SS 316/316L contact parts, offering corrosion resistance and easy maintenance. Users benefit from a potent blend of efficiency and versatility with options like interchangeable impellers and a control panel with speed adjustments for precise milling.

Benefits

  • Ensures consistent product quality by delivering uniform granule size and mixing.
  • Minimizes contamination risks with seamless, tool-free design and GMP compliance.
  • Reduces operational costs through lower energy consumption and maintenance needs.
  • Enhances production efficiency with high-capacity operation and minimal fine generation.
  • Protects operator safety with low noise levels and ergonomic design.

General


Applications
Chemicals,Nutraceuticals,Food,Pharmaceuticals
End products
Protein powders,Food additives,Granules,Vitamin supplements,Spices,Tablets,Seasoning blends,Flavoring agents,Capsules
Steps before
Purification,Drying,Emulsification,Grinding
Steps after
Uniform Mixing,Tablet Pressing,Coating,Packing
Input ingredients
solids,granules,pharmaceutical ingredients,nutraceutical ingredients,chemical materials,food ingredients
Output ingredients
milled granules,uniform particles,size-reduced solids
Market info

Technical Specifications


Output
200 to 400 Kg/Hr
Output
600 to 800 Kg/Hr
Motor Power
5 HP
Motor Power
7.5 HP
Blade Speed
150 to 3000 RPM
Sieve Sizes
1 to 12 mm
Vacuum Rated Design
Yes
Milling Capacity
Higher with lesser fine generation
Contact Parts Material
SS 316/316L
Non-Contact Parts Material
SS 304
Design,Construction
Robust and Rigid
Control Panel
Potentiometer for Speed Control
Impeller Design
Interchangeable
Compliance
21 CFR Part 11
GMP Model
cGMP

Operating Characteristics


Milling Capacity
Higher
Batch vs. continuous operation
Batch
Black Particle Generation
None
Noise Levels
Low
Automation level
Manual / Interchangeable Impeller Design

Material Compatibility


Abrasion resistance
High
Biological compatibility
Yes
Cleanability
CIP Compatible
Corrosive resistance (e.g. acids)
Yes
Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Compact footprint
Smaller,compact,and requires less maintenance
Discharge method
Seamless and tool-free design
Control panel type
Potentiometer for speed control and adjustment
Machine Size
Sigma Mill 400 and Sigma Mill 800
Construction Material
Contact parts (SS 316/316L) and non-contact parts (SS 304)

Custom Options


Control panel type
Potentiometer for speed control and adjustment
Milling capacity
Higher milling capacity with lesser fine generation
Design and Manufacturing Standards
21 CFR Part 11 compliance
Milling Screen Types
Wide range available
Impeller Design
Interchangeable impeller design
Vacuum Rated Design
Yes
Drive Mechanism
Top drive mechanism