Containment capsule filler for highly potent drugs
Achieve complete operator safety while encapsulating potent pharmaceutical formulations with advanced containment features, ensuring secure production for high-value drugs.
Fills and Contains Highly Potent Capsules
The SECUREFILL 40T from ACG is a high-containment capsule filling machine that excels in processing highly potent active pharmaceutical ingredients (HPAPIs). This unit is specifically designed for the pharmaceutical and biotech industries, providing safe and efficient encapsulation for oncological, hormonal, and antiviral formulations. Its monoblock structure, constructed from SS316L, includes HEPA filters and glove ports, ensuring a negative pressure environment to fully contain substances within an occupational exposure limit of 1-10 µg/m³. The SECUREFILL 40T facilitates medium to large-scale batch production, achieving rates of up to 40,000 capsules per hour. It supports various filling options including pellets, tablets, micro-tablets, and soft gels. Integrated with check-weighers, metal detectors, and de-dusters, it ensures smooth operation within containment conditions. The wet-in-place cleaning system effectively neutralizes formulation residues, aiding easy maintenance and operator safety. Certified up to OEB level 4, this machine complies with stringent safety standards, making it ideal for producing critical drugs like lenalidomide and testosterone replacement tablets.
Benefits
- Ensures operator safety with complete containment, minimizing exposure to potent pharmaceuticals.
- Increases production efficiency with a capacity of up to 40,000 capsules per hour.
- Facilitates compliance with OEB level 4, ensuring adherence to safety standards for handling HPAPIs.
- Simplifies cleaning processes with a wet-in-place system, reducing downtime for maintenance.
- Enhances product consistency and quality control through integration with check-weighers and metal detectors.
- Applications
- Soft gels,Oncological formulations,Hormonal formulations,Pellets,Tablets,Micro-tablets,Biopharmaceuticals,Capsules,Hpapis,Antiviral formulations,Pharmaceuticals
- End products
- Biopharmaceutical drugs,Hormone replacement therapy capsules,Chemotherapy capsules,Antiviral micro-tablets,Hormone therapy soft gels,Tamoxifen,Protease inhibitors,Rituximab,Immune modulators,Oncological capsules,Antiviral medication capsules,Oncology drugs,Oseltamivir,Lenalidomide,Testosterone replacement tablets
- Steps before
- Granulation,Blending,Mixing,Weighing,Formulation
- Steps after
- Check-weighing,Metal detection,De-dusting,Packaging,Serialisation
- Input ingredients
- oncological formulations,hormonal formulations,biopharmaceutical formulations,antiviral formulations,highly potent active pharmaceutical ingredients (HPAPIs),pellets,tablets,micro-tablets,soft gels
- Output ingredients
- filled capsules
- Market info
- ACG World is known for manufacturing capsules and capsule filling machines, providing integrated pharmaceutical solutions with a strong reputation for innovation, quality, and comprehensive service offerings in the pharmaceutical manufacturing industry.
- Capsule sizes
- 00 - 5
- Maximum speed
- 40,000 capsules/hr
- OEL (Occupational Exposure Limit)
- 1-10 µg/m3
- Material
- SS316L
- Containment level
- OEB up to Level 4
- Containment level
- OEB up to level 4
- Filling type
- Pellets,tablets,micro-tablets,capsules,soft gels
- Automation level
- PLC-controlled
- Batch vs. continuous operation
- Batch
- Cleaning method
- Wet-in-place system (WIP)
- Safety features
- Glove ports,HEPA filters,RTP
- Negative pressure environment
- Maintained
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Contaminant risk
- High potency APIs,oncological,hormonal,biopharmaceutical,antiviral formulations
- OEB Compliance
- Up to Level 4
- Material of construction
- SS316L
- Containment Type
- Monoblock structure
- HEPA Filters
- Included
- Control Type
- Negative pressure environment
- Control panel type
- HMI/PLC interface
- Integration possibilities
- Check-weighers,metal detectors,de-dusters
- Glove ports
- Customizable for operation
- Negative pressure environment
- Adjustable settings
- Capsule size flexibility
- 00 to 5