Let's make softgel capsules
Softgel capsules fast-track the delivery of medication to the bloodstream. Unlike solid pills, they do not need to be broken down by the body before the drugs can be absorbed. Moreover, they are optimal vehicles for oils and fat-soluble formulations that cannot be compressed into tablets.
What softgel capsules equipment do you need?
Automatic medical forming and sealing blister machine for packing capsules and tablets
Product safety is very importa...
Cold forming aluminum blister machine for capsules
Working with capsules, you have high standards regarding packaging. Th...
Effective Visual Inspection System for Capsules
The attribute of capsule packing is a critical parameter that controls the...
Granulation line for pharmaceutical solid dosage forms
Granulation is a common technique in production of pharmaceutical ...
Industrial scale tablet coater
During the coating process, tablets pass many stages that can make them wet and sticky or cra...
Fluid bed dryer for pharmaceutical solid dosage form
Fluid bed drying is a pharmaceutical process carried out to reduce t...
Industrial high shear mixer granulator for drug formation
It is rather difficult to successfully produce a pharmaceutica...
Tablet coater for laboratory scale
Tablet coating can be applied for adding colours or glosses, or based around sugar in or...
Tablet counting machine
Production of pharmaceutical solid dosage forms usually require complete accuracy, flexibility, and c...
Pharmaceutical bottle unscrambler
Pharmaceutical packaging industry requires the ability to quickly manage the process yet ...
Dessicant inserting machine
Desiccant canisters play an important role in the pharmaceutical and nutraceutical industries. T...
Metal detector for bottles
For metal contamination detection in finished products that are bottled, traditional solutions re...
Metal detector for tablets and capsules
Identification of metallic contaminants is a vital part of pharmaceutical quality c...
Automatic filling line for solid doses
For medium-scale production of solid doses such as tablets, capsules, and softgels t...
Electronic capsule counter
For lab work or small batch production, hand counting of solid doses into dispensing containers i...
Brand protection software
Efficient security systems are desirable to prevent, detect and mitigate the actions of unscrupulo...
Semi-automatic case packer
Pharmaceutical products require complete traceability throughout the production cycle. For smalle...
Serial Data Managing Database
Managing serialization data is a vital part of accurate reporting and product integrity in the...
Stand-alone aggregation station
The aggregation of pharmaceutical products for tracking purposes is already compulsory in ma...
Serialization coding and labeling equipment
In the pharmaceutical industry, product serialization is the cornerstone of al...
Laboratory scale soft gelatin capsule machine
Softgel (or soft gelatin) capsules are a very popular method for providing o...
Softgel tumble dryer
Softgel (or soft gelatin) capsules are a very popular means of delivering oral doses in the pharmaceutic...
Softgel capsules polisher
The final stage in high quality softgel (or soft gelatin) capsule production is the capsule polish...
Softgel drying tunnel
Softgel capsules require a controlled secondary drying to reduce water content in the capsule to levels...
Continuous in-line softgel drying system
High output softgel (or soft gelatin) capsule encapsulating machines can operate b...
Automatic soft gelatin capsule machines
Soft gelatin (or softgel) capsules have become a popular mode of oral liquid dosing...
Gelatin melters and tanks
When producing high quality softgels its important that the gelatin base is processed and stored c...
Conical mill for drug formulation
The efficient size reduction of granular powders is a key step in many pharmaceutical pro...
Granulation line of mixer and fluid bed dryer
A complete granulation line allows for the mixing and granulation of pharmac...
Microencapsulation system for your drug delivery system
Whether you want to improve the stability of nutrients, protect a...
High capacity capsule filler
In the highest volume pharmaceutical production environments, capsule filling needs to be extre...
Scale up capsule filler
For higher production volumes of pharmaceutical capsules, speed, accuracy and reliability of producti...
Rotary tablet press
For pharmaceutical tablet producers looking to reduce waste, costs and  increase production volume, a hig...
Fluid bed dryer for production scale
Fluidized bed drying (FBD) is a common process in the pharmaceutical industry for dryi...
Fluid bed dryer for lab scale
Fluidised bed drying (FBD) is a common process in the pharmaceutical industry for drying compo...
Fluid bed dryer and mixer for lab scale
Designed for pharmaceutical R&D, a lab-scale fluid bed dryer and mixer/granulat...
High-shear mixer
For the efficient mixing of larger batches of pharmaceutical compounds and high-shear mixer provides the opti...
Entry-level high-shear mixer for drug formulation
For pilot and lab-scale pharmaceutical formulations, a high-shear granu...
Waste minimization weight sorter for tablets & capsules
For medium scale production, you can improve line efficiency and ...
High capacity weight sorter for tablets & capsules
By employing a weight sorter that is fully flexible and able to ha...
Benchtop weight sorter for tablets & capsules
For laboratory pharmaceutical R&D work or use in clinical trials, a...
Versatile weight sorter for tablets & capsules
Saving costs and improved production efficiencies are possible by opti...
Case packer for stackable products
Are you packing square or stackable products into corrugated cases? An automated case pa...
Automatic straddle stretch wrapper
Select from an industry leading range of automatic stretch wrappers to prepare up to 110...
Case erector
To overcome common cases of manufacturing variations and optimize your packaging line, you need to be able to cou...
Case sealer
Automatic sealing of corrugated cases can speed up your production process. You can seal with tape or, in case you...
Tray erector
Corrugated trays come in many forms and sizes.  Automate the process of erecting the trays to ensure consistent q...
Lid applicator for corrugated cases
For your secondary packaging, you may be considering packing into boxes that require a ...
Economic turn-table stretch wrapper
Wrap up to 20 loads per day on an easy-to-use turn-table that ensures safe-to-ship loads.
Semi-automatic turn-table stretch wrapper
For your most common stretch wrapping requirements, consider a semi-automatic tu...
Semi-automatic straddle stretch wrapper
If you need to wrap lightweight, heavy, tall or unstable loads, a semi-automatic st...
Automatic turn-table stretch wrapper
These stretch wrappers are some of the most versatile, automatic turn-table stretch wr...
Automatic ring-straddle stretch wrapper
Imagine a stretch wrapper that can wrap up to 180 loads per hour without putting to...
High-speed blister machine
If you are looking for a compact machine that produces blisters with an output of up to 700 blist...
Horizontal intermittent motion cartoner
User-friendly cartooning solution with an intermittent motion for a wide range of p...
Horizontal continuous motion cartoner
An automatic cartoning machine designed for both high-speed operations and medium pac...
Entry-level blister machine
A start-up solution for contract packing and generics manufacturing with an easy-to-get upgrade ...
Compact blister machine
A compact blister machine ideal for packing tablets, capsules, ampoules and syringes and other applic...
Case packer for cartons and bundles
Pack cartons and bundles into RSC (Regular Slotted Case) cases and perform functions li...
Stretch bander
A compact wrapping machine to seal your boxes with a max speed of 50 packs per minute.
Vertical cartoner
A cartoning solution that can be operated in either continuous or intermittent mode depending on the carton...
Checkweigher for capsules
The new interactive indicator unit allows for even easier use. High-rigidity weighcells have been ...
There is currently no equipment listed with your specified properties, but we are sure we can help you. Try us! Contact us
Tell us about your production challenge
Primary ingredients to manufacture a softgel capsule
The essential ingredients of a softgel capsule are gelatin, water, and a plasticizer such as glycerin or sorbitol. The presence of water means that the API formula must not be hydrophilic because it would deteriorate the shell over time.
The capsule is typically transparent, so adding opacifiers protects your fill matrix from sunlight. Preservatives, meanwhile, ensure that your capsules remain free from bacteria. Finally, you may also incorporate colorants and flavorings to make the final product more palatable.
Preparing the gelatin base for softgels
The propensity of gelatin to melt in warm environments and form a gel while it is cooling down makes it an ideal substance for the administration of medication in a liquid or semisolid state.
Gelatin is an effective combining agent that holds the structure of the capsule together. Granulated gelatin is added to a blend of water and plasticizing substance, and the mixture is heated to around 60 °C until the particles are fully dissolved.
Inspect the capsules for air bubbles
Air pockets pose a risk to the production of softgel capsules. Bubbles weaken the structure of the shell and may lead to leakage of the drug.
This manufacturing defect typically occurs when your blending process is not conducted at the right temperature or for a suitable duration. The air inside the base components naturally rises to the surface and escapes the mixture, but inadequate heating leads to trapped bubbles.
Using vegan materials for softgels
You can substitute the gelatin to produce a vegetable-based softgel capsule. Derived from animal bone or connective tissue, gelatin makes traditional formulations incompatible with vegan requirements.
Hypromellose (HMPC) and Tapioca starch present viable alternatives made from vegetable cellulose. Besides using non-animal materials, vegan softgel capsules offer a higher bioavailability rate compared with gelatin options. Their low-moisture content also makes them less brittle in reduced humidity.
Processing steps involved in softgel capsules making
Let's talk about your project!