Containment blister packaging for highly potent Apis
In pharmaceutical manufacturing, especially when dealing with highly potent active pharmaceutical ingredients (HPAPIs), maintaining a safe working environment is crucial. Ensuring containment during blister packaging is essential to protect operators from exposure and prevent cross-contamination of products.
Ensure safe blister packaging of Hpapis.
The SECUREBLIS MINI from ACG World is a containment solution designed specifically for blister packaging solid dosage forms, such as tablets, hard capsules, and soft gelatine capsules, that contain highly potent active pharmaceutical ingredients (HPAPIs). It operates under negative pressure to contain HPAPIs, aiding compliance with Operational Exposure Band (OEB) 3 standards. The system includes glove ports at various locations for safe manual interventions without breaching containment. HEPA filters assure a safe working environment by eliminating cross-contamination risks. An automated wet-in-place (WIP) system with strategically placed nozzles ensures that drug particles are settled during the blister packaging process, making cleaning and changeover quicker and safer. Additional safety interlocks ensure the system operates under contained conditions at all times, while easy integration with product loading systems enhances operator safety during tablet or capsule loading.
Benefits
- Complies with OEB 3 standards for safety
- Minimizes operator exposure to HPAPIs
- HEPA filters ensure zero cross-contamination
- Automated WIP system for efficient cleaning and changeover
- Easy product loading integration for enhanced safety