Making Liquid Dosage Forms
Find innovative liquid dosage forms equipment and connect directly with world-leading technology suppliers
Liquid dosage forms are designed for easy absorption. The body quickly carries the active ingredients through the system and triggers the required response. But the greatest advantage of this medicinal type is its flexibility in formulation and dispensation. From lotions and syrups to drops and sprays, liquid solutions can be adapted to different administration routes including parenteral, topical, and oral. The fundamental liquid dosage manufacturing process involves dissolving or suspending solutes in a fluid. But that is not enough. A precise blend of excipients is needed to make the medicine go down.
Top picks for liquid dosage forms
Laboratory filling system for liquid and creamy products
In laboratory settings, filling a variety of liquid, creamy, and...
High precision dosing system for liquid media
Producing confectionery and bakery products implies mixing large amounts of ...
Sterile liquid preparation system for pharmaceutical use
In pharmaceutical production, maintaining aseptic conditions dur...
Pneumatic dosing syringes for precise liquid dispensing
In industrial settings where precision dosing of liquids is criti...
Select your liquid dosage forms process
Tell us about your production challenge
Use water or pure alcohol as a solution in the liquid dosage manufacturing process
The liquid dosage form is prepared by dissolving the active ingredient within a liquid vehicle to form a solution. Depending on the type of liquid vehicle used, you obtain either aqueous or non-aqueous solutions.
The aqueous solutions have water as the solvent, while the non-aqueous solutions have hydro-alcoholic (water and alcohol as solvents) and alcohol (only alcohol as solvent). Elixirs and tinctures are examples of hydro-alcoholic solutions. The concentration of alcohol in elixirs is 3%-25%, while the concentration of alcohol in tinctures is 25%-60%.
Apply size reduction to raw materials to facilitate solubility
Drops, syrups, elixirs, and draughts are monophasic liquid dosage forms, retaining the components in a single liquid phase. The APIs in most dosage forms of this type are weak acids or weak bases with low solubility properties. The formulation, therefore, requires adjustment of pH levels.
One method to improve solubility is by reducing the particle size of pharmaceutical powders. Using a mill or a spray drying system, grind the materials to 10 microns or less.
Apply gravimetric measurement in the liquid dosage manufacturing process
The volumetric measurement risks a high variability in liquids as the ingredients may be subjected to volume contraction or expansion.
The gravimetric method bypasses the effects of temperature and ambient forces acting on the ingredients. By measuring the density of the total contents, the technique gives a more reliable reading of the liquid dosage before filling and packing.
Which liquid dosage forms technology do you need?
Filling and capping solution for oral liquid products
Manufacturers of oral liquid products frequently encounter the need...
Inline high shear mixer for low to medium viscosity liquids
When creating emulsions or mixing large quantities of powder...
Liquid filling system for medical and pharmaceutical products
Efficient production of medical and pharmaceutical product...
Liquid dosing and assembly platform for pharmaceutical products
In pharmaceutical production, precise dosing and assembl...
Liquid dispensing isolator for sterile environments
When dispensing pre-sterile liquids, it is crucial to maintain a ster...
Industrial liquid filler for small to medium volume operations
In manufacturing environments where precision in liquid f...
Sterile filling line for liquid and powder
In pharmaceutical manufacturing, ensuring sterile filling of liquid and powder ...
Cip workstation for pharmaceutical liquid preparation systems
In pharmaceutical production, maintaining the cleanliness ...
Sterile liquid preparation system for pharmaceutical use
In pharmaceutical production, maintaining aseptic conditions dur...
Aseptic liquid transfer connection system
Ensuring sterile liquid transfer during pharmaceutical manufacturing is crucial ...
Liquid capsule filling for r&d and pilot-scale production
In R&D or pilot-scale production, ensuring the integrity ...
Single-chamber freeze dryer for liquid products
When dealing with large-scale drying of liquids such as milk or collagen g...
Blow/fill/seal packaging system for sterile liquid products
In the pharmaceutical and healthcare industries, maintaining...
Blow/fill/seal system for aseptic liquid packaging
In industries like pharmaceuticals and nutritional supplements, ensuri...
Oral liquid bottle filling & capping system
In pharmaceutical production, ensuring the accurate filling and secure capping...
Vertical ultrasonic washing system for oral liquid bottles
In pharmaceutical manufacturing, maintaining the cleanliness ...
Large-volume sterile liquid storage solution
In bioprocessing and vaccine production, large volumes of cell culture media,...
Aseptic tank with blending function for liquid food storage
Ensuring safe and efficient aseptic storage and blending of ...
Moist heat sterilizer for liquid preparation
In pharmaceutical manufacturing, sterilization of liquid preparations is cruc...
Laboratory liquid viewer for colored glass bottles
In the pharmaceutical industry, an inspection to detect any particulat...
Laboratory liquid viewer for varying light conditions
In the pharmaceutical industry, you must inspect liquids in vials o...
Laboratory liquid viewer for transparent glass bottles
Impurities like hair, fibers, or glass, sourced from the environme...
Inline batch mixer for solids and liquids
Several issues often arise when your process requires batch-wise mixing of powde...
Dilution system for two or more liquids in one pass
Onsite dilution of liquid process ingredients has historically been a...
Capsule banding system for tamper-evident sealing
In the pharmaceutical industry, ensuring the integrity of capsules fill...
Thermoforming solution for clinical trials
In clinical trials and short production runs, precision in packaging is paramou...
Filling solution for non-injectable pharmaceutical products
In the pharmaceutical industry, ensuring accurate and contam...
Rotary filling system for Rtu vials in pharma production
In clinical and early-stage pharmaceutical production, there is ...
Filling and closing solution for plastic bottles
Producing pharmaceutical, cosmetic, or other liquid products often requir...
Semi-automatic timed flow filler for aqueous solutions
In the packaging industry, filling thin and light oil liquids accu...
Form, fill, and seal system for single-use pouches
When producing single-use pouches for products like ketchup, lotions, ...
Continuous in-line blender for beverage industry
In the beverage industry, achieving consistent mixing of multi-component ...
High shear mixer for low viscosity products
When producing low viscosity products like juice, soft drinks, or liquid food,...
Ultraclean filling monoblocks for food industry
When filling food products in round or shaped bottles, maintaining sterili...
X-ray inspection module for pre-filled syringe needles
Ensuring the integrity and sterility of pre-filled syringes requir...
Industrial fluid and paste preparation system
When preparing fluids and pastes for industrial applications, ensuring consi...
Accurate pharmaceutical dispenser for high-viscosity fluids
In pharmaceutical production, precise dosing of high-viscosi...
Automatic inspection and leak test for pharma containers
In the pharmaceutical industry, maintaining the integrity and sa...
Automatic leak detection system for pharmaceutical containers
Ensuring the integrity of sealed pharmaceutical containers...
Modular pharmaceutical formulation systems
Pharmaceutical formulation processes require high flexibility and efficiency du...
Multipurpose ultra high temperature (uht) pilot plants
In the development and testing of liquid food products, achieving ...
Reciprocating plastic bottle blow-fill-seal system
In pharmaceutical production, maintaining a sterile environment while ...
Benchtop peristaltic dispenser
When you fill vials and ampoules, high standards of hygiene are required to avoid the risk of...
Manual ampoule filler
When you fill ampoules it is essential to avoid wetting the inside walls of the container, as it may af...
Benchtop piston filling equipment for vials in trays
Vials are difficult to fill individually through manual methods due ...
Manual stoppering equipment for pre-filled syringes
Air present in the empty space of pre-filled syringes may prevent you...
GMP homogenizing system
Manufacturers need production mixing equipment that is capable, flexible, and easy to maintain. Accur...
Small-scale laboratory dispersing machine
Developing and validating new processes requires reliable and highly versatile e...
Start-up sterile filling line for ophthalmics
Commencing ophthalmic production requires sterile conditions and accurate me...
High-pressure homogenizer
When processes call for homogenized emulsions with extremely fine particle sizes the traditional t...
Stickpack Machine
If you are looking to pack your product into stick packs from 17 x 40 mm to 100 x 200 mm in size, you may b...
Sachet Machine
If you want to pack into eye-catching 4-side sealed sachets between 40×50 mm and 250×200 mm in size, ...
Disposable tank liners
Manufacturers in the bioprocessing industries are increasingly turning to single use solutions for the...
Sterile filling line for ophthalmics
Demanding very high standards, the ophthalmic market requires quality solutions for fi...
Corundum disk mill
Wet milling and grinding of viscous liquids or pastes containing solid particles such as peanut butter,mus...
Economic dispersing machine for emulsions and suspensions
For products of medium viscosity and relatively consistent par...
Dispersing machine for very fine emulsions and suspensions
For continuous high performance mixing of solid and liquid ra...
Continuous homogenizing system
Certain mixing tasks present unique challenges and manufacturers need equipment that is speci...
High accuracy homogenizing system
When extremely high accuracy is required in your recipe or formulation traditional mixing...
Continuous kneader
Effective mixing of highly viscous products with extremely high solids content can be difficult and the re...
Batch dispersing machine for bottom entry into vessels
When your process requires high performance mixing or dispersion b...
Dust-free continuous homogenizing system
Producers in a wide variety of industries benefit from equipment that can continuo...
Pilot dispersing machine for testing and scale-up
Innovators in process development need laboratory equipment that helps ...
In-line laboratory dispersing machine
Innovators in a wide variety of industries need laboratory equipment on which process...
Agitator for medium viscosity media
Mixing fluids of medium viscosity for many production processes requires an agitator wi...
Soya milk production system
In the production of dairy alternatives, such as soya milk, maintaining product quality and cons...
Linear vial washer for injectable drug containers
In pharmaceutical manufacturing, maintaining sterility and cleanliness ...
In-line filling system for pharmaceutical products
In many pharmaceutical applications, complete control over packaging p...
Automatic bottle filling and capping line
Industrial settings requiring efficient and precise bottle filling and capping o...
Pharmaceutical isolator system for aseptic production
In the pharmaceutical industry, ensuring the sterility of drug prod...
Multi-effect water distillator for pharmaceutical applications
In pharmaceutical production, ensuring high-quality and s...
Single-use mixer for buffer sterile mixing
In bioprocessing applications, maintaining sterile conditions while mixing buff...
Ophthalmic filling solution for eye drops
In ophthalmic manufacturing, maintaining sterility and accuracy in the filling p...
Cannabis nanoemulsification system for high-precision production
Producing water-soluble cannabis products like beverage...
Semi-automatic vial crimper
In a small production line, crimping vials manually can cause fatigue to your operator due to mu...
Benchtop ampoule opening and closing equipment
The procedure for opening or closing ampoules requires you to handle gas an...
Labeling machine for ampoules
It’s essential for pharmaceutical companies to provide the highest quality ampoules to custome...
Syrup preparation tank
Syrups and suspensions are typically produced under the same high-quality conditions as used for steri...
Loading basket for GMP washer
To ensure perfect cleaning of contact parts they must be placed in the GMP washer in such a wa...
Bulk chamber washer
The production of cosmetics, nutraceuticals or unregulated pharmaceuticals often requires the cleaning an...
Entry-level chamber washer
When cleaning smaller products contacting filling or compressing components used in the productio...
Feeder with flexible wall hopper
The varying properties of dry powder products mean that specialized feeders are required fo...
Small feeder with flexible wall hopper
In many laboratory applications and production processes, smaller quantities of powd...
Colloid mill
For creating extremely fine emulsions and high quality dispersions a high pressure homogenizer is often chosen. ...
Dispersing machine for emulsions and suspensions
Equipment operating under the rotor/stator principal is often employed wh...
Ultra-fine dispersing machine for emulsions and suspensions
Producing the finest micro-emulsions and suspensions require...
Cone mill machine
When your raw materials include agglomorated suspensions of grainy or crystalline solids and your process n...
Horizontal kneader
For high viscosity products, better results and reduced process times can be achieved with kneading type r...
Vertical kneader
Production of highly viscous products with high solid content often benefits from kneading processes rather t...
Batch dispersing machine
Equipment operating under the rotor/stator principal is often employed when more traditional methods...
Batch dispersing machine for abrasive products
For mixing and dispersing tasks that cannot be completed by conventional st...
Cost-effective homogenizing and emulsifying system
Manufacturers of cosmetic products need mixing equipment that is capab...
Laboratory dispersing machine for low-viscous masses
Laboratory mixers have not always been easy to work with. Getting a...
Jet flow agitator for high-viscosity media
Processes including homogenization, dispersing, suspension, emulsification and ...
Agitator for low viscosity media
Reliably agitating fluids in open or pressure-less vessels in a laboratory or small scale p...
Small bottle checkweigher
Any small-diameter bottle, containing prescription medication or cosmetic applications, can be pro...
Versatile checkweigher
This Versatile checkweigher is equipped with a highly versatile strain gauge load cell. It is also sui...