Rotary filling system for Rtu vials in pharma production
Optimize your sterile liquid and powder handling with a versatile system designed to ensure aseptic conditions and precise filling, tailored to streamline high-speed pharmaceutical production lines.

Fills, Weighs, and Decontaminates Sterile Pharmaceutical Products
The MICRO BI Rotary Filling System from Comecer is designed specifically for pharmaceutical and biologics manufacturers, offering an integrated solution for aseptic filling of both liquid and powder formulations. This system is distinguished by its ability to maintain consistent batch quality through intelligent servo-driven technology, minimizing error and enhancing efficiency. It caters to a diverse range of applications, producing biopharmaceutical vials, insulin injectables, vaccines, and radiolabeled compounds. With filling speeds of up to 200 units per minute, MICRO BI effectively eliminates bottlenecks in high-speed, continuous production settings.
The system seamlessly integrates into your existing production line, combining rotary filling capabilities with an aseptic isolator environment. Its compact design optimizes the use of production floor space, while full servo automation enhances operational precision and repeatability. Constructed with corrosion-resistant stainless steel, and equipped with H14 filters and a VPHP generator, the MICRO BI ensures compliance with Class 3 containment and ISO 10648-02 standards.
This equipment is also designed for ease of maintenance and cleaning, featuring spray balls and guns for efficient decontamination. With configurable options for filling pumps and closure types, and backed by robust automation support through Baseline Keba controls, MICRO BI offers customization to meet tailored production needs, supported by extensive documentation and validation resources.
Benefits
- Ensures sterility and operator safety with integrated aseptic isolator, enhancing product quality.
- Maximizes production efficiency with selectable filling speeds, minimizing bottlenecks in high-volume operations.
- Reduces labor costs and error rates through full servo automation and intelligent control features.
- Meets stringent industry standards with GMP-compliant designs and Class 3 containment levels.
- Facilitates swift and thorough cleaning, minimizing downtime for maintenance and ensuring contamination-free operation.
- Applications
- Liquid formulations,Pharmaceutical powder,Radiopharmaceuticals,Pharmaceutical injectables,Biopharmaceuticals
- End products
- Vaccines,Biopharmaceutical vials,Insulin injectables,Radiolabeled compounds,Sterile saline solutions,Antibiotic powders
- Steps before
- Compounding,Aseptic Preparation,Vial Preparation
- Steps after
- Sterilization,Packaging,Batch Consistency Verification
- Input ingredients
- RTU vials,clinical and early-stage pharma production materials,liquids,powders,trayed vials,nested vials,syringes,cartridges
- Output ingredients
- filled vials,filled syringes,filled cartridges,stoppered vials,closed vials
- Market info
- Comecer is known for manufacturing advanced containment and isolation systems, particularly in the pharmaceutical and nuclear medicine sectors, with expertise in custom-engineered equipment, ensuring high safety and compliance standards.
- Filling speed
- 50 or 200 units per minute
- Filling method
- Servo-driven design
- Air flow practice
- ISO 5
- Containment level
- Class 3,ISO 10648-02
- Leak rate
- ,lt
- 1%
- Working Mechanism
- Rotary filling system
- Integrated Steps
- Filling,closing,capping
- CIP/SIP
- CIP principles for cleanability
- Batch vs continuous operation
- Batch
- Changeover Time
- Optimized for quick changeover
- Automation level
- PLC / Servo-driven
- Containment Level
- Class 3,ISO 10648-02
- Cleaning Method
- Spray Balls and Spray guns
- Cleanability
- Able to accommodate aseptic conditions and easy cleaning via spray balls and guns
- Corrosive resistance (e.g. acids)
- Stainless steel AISI 316L
- Biological compatibility
- Suitable for aseptic pharmaceutical and biologics injectables
- Container Size and Shape
- RTU Vials
- ISO 10648-02
- Class 3 containment level
- Compact footprint
- Space-saving design
- Control panel type
- PC based touch panel screen
- Discharge method
- Trayed vials and/or nested vials/syringes/cartridges
- Isolator walls material
- Stainless steel AISI 316L with internal finish Mirror Brite
- Glove ports
- Independent safety barrier with Integrated Glove Integrity Tester
- Doors material
- 12 mm thick tempered glass with inflatable gaskets
- Filtration grade
- H14 filters IN / OUT
- Filling speed options
- 50 or 200 units per minute
- Control panel type
- PC based touch panel screen
- Pumps type options
- Peristaltic and Piston pumps
- Machine configuration
- Isolator ready / RABS configurations
- Integration compatibility
- ATS Scientific Products rotary filler with Comecer aseptic isolator