Flow through dissolution system for drug products
Capture real-time dissolution behavior with high-resolution imaging, providing in-depth insights into drug release and formulation refinement. Ideal for tackling complex dissolution challenges, this system enhances analysis capabilities with dual-wavelength UV and visible surface imaging.
Captures High-Resolution Drug Dissolution Images
The SDi2 High-Resolution Flow-Through Dissolution System from Pion Inc. offers a cutting-edge solution for researchers and pharmaceutical manufacturers seeking precise analysis of drug dissolution. This system uniquely combines ultra-violet and visible surface imaging to capture the dissolution process in real-time, providing unmatched insights into the physical behavior of drug products. It is ideal for applications involving pharmaceutical tablets, drug substances, capsules, and oral formulations.
The SDi2 employs dual flow cells, allowing flexible study of both solid and powder dosage forms with automated control for seamless switching between two dissolution media. This versatility supports a range of analysis, including the impact of drug swelling and disintegration on release profiles. Integrated fluidics ensure compact operation, while the system’s high-resolution 2-D video outputs facilitate detailed observation and refinement of drug formulations.
With a focus on efficiency and integration, the SDi2 is designed for easy incorporation into laboratory and R&D environments, supported by Pion’s robust engineering expertise. By providing critical visualization and analysis capabilities, the SDi2 contributes to the optimization of drug development processes, meeting the stringent needs of pharmaceutical, biotech, and chemical industries.
Benefits
- Enhances drug formulation accuracy with real-time high-resolution imaging and analysis.
- Facilitates comprehensive understanding of dissolution processes, aiding in formulation optimization.
- Increases research efficiency with automated control of multiple dissolution media.
- Supports diverse pharmaceutical applications, from tablets to powders, ensuring versatility.
- Reduces experimental errors by visualizing and measuring physical drug behaviors directly.
- Applications
- Drug substances,Oral formulations,Capsules,Pharmaceutical tablets
- End products
- Steps before
- Compound Preparation,Formulation Development,Sample Dispersion
- Steps after
- Data Analysis,Formulation Adjustment,Presentation Preparation,Data Export
- Input ingredients
- drug products,dosage forms,powder,tablets,capsules
- Output ingredients
- high-resolution images,UV imaging,drug release profiles,videos,quantitative analysis,drug concentration release profiles,false color images
- Market info
- Imaging Technology
- High resolution,visible,and UV
- Automation
- Automated control with dual flow cells
- Compact Flow Cell
- Raman compatible
- Dual Wavelength Capacity
- Ultra-violet and visible
- Video Output
- 2-D high-resolution videos
- Swelling and Disintegration Analysis
- Quantitative analysis for tablets and capsules
- Dissolution Media
- Switching up to two media in a single assay
- Working mechanism
- Flow through dissolution system
- Integration steps
- UV and visible imaging
- Automation level
- Automated media switching
- Compact design
- Compact flow cell
- Batch vs. continuous operation
- Continuous monitoring with real-time imaging
- Compact footprint
- Yes
- Control panel type
- Integrated fluidics control
- Dual wavelength capacity
- UV,Visible
- Flow cell type
- Raman compatible
- Flow cell configuration
- Two distinct flow cells
- Software compatibility
- SDi2 Analysis Software
- Media switching
- Automated control up to two dissolution media