Encapsulation equipment for microbeads and microcapsules
Achieve precise encapsulation of active ingredients and materials with tight particle size control, enhancing product quality and efficiency—ideal for developing innovative microbeads and microcapsules in diverse applications.
Produces Microbeads and Microcapsules
The Encapsulator B-390/B-395 from Buchi offers precise control over microbead and microcapsule production, vital for pharmaceutical, food, and biotech sectors. Specializing in sterile encapsulation, it ensures high-quality droplet formation and bead production for applications ranging from vaccine microbeads to probiotic supplements. Operating on benchtop with a focus on small-scale batch processes, it accommodates particle sizes from 80 μm to 4 mm with a throughput of up to 40 mL/min. Its low-impact encapsulation maintains product integrity, and it integrates smoothly into GMP-compliant production lines, supported by easy maintenance and robust material options for sterilization processes.
Benefits
- Enhances product quality with precise droplet and bead size control.
- Facilitates easy scale-up from R&D to production with flexible batch processes.
- Ensures sterility, crucial for sensitive biopharmaceutical applications.
- Integrates seamlessly into existing GMP-compliant workflows.
- Simplifies cleaning and maintenance with durable, autoclave-compatible materials.
- Applications
- Vitamins,Proteins,Fine chemicals,Environmental applications,Fragrances,Nutraceuticals,Cosmetics,Probiotic bacteria,Biopharmaceuticals,Functional foods,Controlled release additives,Cell transplantation,Flavors,Pharmaceuticals
- End products
- Protein gel beads,Bioengineered skin grafts,Encapsulated aromatherapy oils,Encapsulated essential oils,Cosmetic serum beads,Sustained-release drug capsules,Vaccine microbeads,Encapsulated omega-3 supplements,Probiotic bead supplements,Bioreactor microorganisms,Anti-pollution microcapsules,Vitamin c microcapsules,Flavor-infused oil droplets,Controlled-release pesticide beads,Fragrance encapsulated powder
- Steps before
- Material preparation,Sample mixing,Active ingredient formulation
- Steps after
- Sterile encapsulation,Particle size distribution analysis
- Input ingredients
- active ingredients,cells,microorganisms,pharma samples,food samples,high viscose solutions,small sample quantities
- Output ingredients
- microbeads,microcapsules,matrix beads,core shell capsules,submicron particles
- Market info
- Buchi is renowned for its expertise in laboratory and industrial solutions, particularly in producing high-quality equipment for chemical analysis and lab processes, known for precision and reliability in the pharmaceutical, chemical, and food industries.
- Capsule type
- Matrix beads or core shell capsules
- Final particle size
- 150 μm - 4 mm
- Productivity
- 1 - 40 mL / min
- Minimum partical size
- 80 μm
- Maximum partical size
- 2000 μm
- Minimum sample throughput
- 0.5 ml/min
- Vibration frequency
- 40 - 6000 Hz
- Working mode
- Open mode / Sterile mode
- Nozzle heater for viscous samples
- Yes / No
- Working mode
- Open mode / Sterile mode
- Nozzle heater for viscous samples
- Yes
- Aseptic encapsulation
- Possible
- Automation level
- Intuitive operation
- Particle size range
- 80 μm - 2000 μm
- Minimum sample throughput
- 0.5 ml/min
- Vibration frequency
- 40 - 6000 Hz
- Encapsulation rate
- 1 - 40 mL / min
- Changeover time
- Quick adaptation for different samples
- Flexibility
- Matrix beads or core shell capsules
- Cleaning method
- Sterile / Aseptic integration
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine footprint
- Compact
- Nozzle size
- 0.08 - 1.00 mm
- Production capacity
- 1 - 40 mL/min
- Encapsulation types
- Matrix beads,Core shell capsules
- Final particle size
- 150 μm - 4 mm
- Working mode
- Open mode / Sterile mode
- Control panel type
- Intuitive operation
- Nozzle system
- Single,Concentric,or Flow Vibration
- Integration possibilities
- GMP-compliant production process