Making Hard Gelatin Capsules
Find innovative production technology for making hard gelatin capsules and connect directly with world-leading specialists
The two-piece capsule is a visual shorthand for all types of medical remedies. Advances in technology have made the production of hard-gelatin capsules a convenient delivery method for drugs and other ingested substances. But the simple solution requires micrometric precision to be manufactured to the proper pharmaceutical standards.
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Dosing accuracy is key to manufacturing hard gelatin capsules
The bright colors that hard-gel capsules are synonymous with come from dyes and edible colorings. However, the main ingredients of the shell are gelatin and plasticizers, which combine at a typical ratio of 1:0.4 using precise dosage technology.
Compared with softgel capsules, the hard gelatin alternatives require fewer components to produce. But your standard formula will also include sugars, an opacifier, and preservatives.
Hygroscopic ingredients weaken the hard-shell structure
The flexibility of hard-gel caps and their relatively long shelf-life make them an ideal solution for the delivery of various drugs. Two-piece capsules can hold a range of powder formulations, tablets, and semisolid solutions.
But hygroscopic agents may lead to cracks in the shell over time, making the production of hard gelatin capsules unsuitable for materials such as silicon dioxide and magnesium carbonate.
Production of hard gelatin capsules is largely impacted by the water content
The mixture to manufacture hard gelatin capsules consists of 14% to 16% demineralized water. Achieving this delicate proportion is key to ensuring that your shells have the proper elasticity to hold their structure and protect the filling.
Too little water will result in brittle capsules, while too much of it risks destabilizing the drug content inside.
Plant-based gelatin alternatives follow the same manufacturing process
Gelatin has been the industry standard in manufacturing hard capsules for nearly a century. But currents drifting away from animal-based ingredients are spurring research into vegetarian alternatives. Substitute materials like starches and carrageenan can be handled with minor modifications to existing technology.
HPMC capsules have emerged as a prime contender to produce plant-based encapsulation formulas. An edible natural polymer, HPMC is made from plant-extracted cellulose. Unlike gelatin, which is non-allergenic foodstuff, HPMC is considered an additive (E460).
Processing steps involved in hard gelatin capsules making
Which hard gelatin capsules technology do you need?
High throughput capsule filling system
Achieve precise, high-speed capsule filling with versatility, ensuring product integ...
Capsule filling system for high volume production
Maximize your capsule production efficiency with a system designed to s...
Tablet and capsule counting system
Need precise counting and filling of solid doses like tablets and capsules in your produ...
High-containment diverter for continuous tablet and capsule filling
Enhance your production line with a versatile solut...
Empty capsule sorting system
Streamline your capsule production by efficiently removing empty and defective capsules, ensuri...
Capsule polisher for pharmaceutical production
Enhance capsule quality and safety by effectively polishing, dedusting, and...
Capsule polisher for pharmaceutical capsules
Ensure your capsules are free from dust and perfectly polished with a solutio...
Tablet and capsule diverter
Streamline your tablet and capsule production with precise container filling and flexible config...
Automatic capsule filling machines
Efficiently fill capsules with precise doses of powders, liquids, and tablets to enhance...
Electronic tablet counter for tablets and capsules
Optimize your production line with precise counting solutions for a wi...
Integrated counting system for tablets and capsules
Streamline your packaging line with a highly versatile system that se...
Capsule selection and feeding unit
Enhance your capsule filling process with precise selection and feeding, ensuring only t...
Capsule filler for pharmaceutical applications
Need precise capsule filling for pharmaceuticals and nutraceuticals? This s...
Precision weight-checking for pharmaceutical capsules
Ensure exact capsule and tablet dosage with high-speed precision we...
Table-top capsule filler for micro-dosing
Achieve precise micro-dosing for pharmaceutical powders and pellets with a user-...
Capsule banding system for tamper-evident sealing
Ensure tamper-evident integrity for capsules by utilizing a precise ban...
High-speed blister packaging with integrated cartoner
Optimize your blister packaging process with a solution that seamle...
Capsule filler for multi-product dosing
Achieve precision and flexibility in capsule filling with a system designed for hig...
High-speed capsule weighing system for quality assurance
Ensure precise capsule weight monitoring and sorting with a syst...
In-process weighing system for capsules and tablets
Ensure precise dosing and consistent quality with a format-free syste...
Powder dosing system for development and small batches
Streamline lab-scale pharmaceutical production with a versatile po...
Commercial capsule filling for small scale production
Efficiently fill and dose capsules with precision, ensuring flawles...
High-containment capsule dosing and filling system
Achieve precise dosing and optimal containment for pharmaceutical prod...
Capsule filling system for powder, pellets, and tablets
Optimize capsule production with rapid dosing changes, minimizing...
Containment capsule filling system for lab and small batch production
Designed to ensure maximum safety in pharmaceutic...
Versatile capsule filler for pharmaceuticals
Effortlessly switch between powder, pellet, and liquid dosing with this adapt...
Empty capsule transfer system
Ensure seamless capsule filling operations by eliminating manual handling and preventing produ...
Filled capsule conveyor system for pharmaceutical production
Ensure gentle and efficient conveying of filled capsules in...
Capsule conveyors for gentle capsule transfer
Streamline your capsule production line with a system designed for high-spee...
Laboratory film coating system for development and clinical batches
Achieve precision in tablet coating with a versatil...
Linear tablet and capsule counter
Ensure precise and efficient bottle filling with a cutting-edge counting system that guar...
Integrated bottling center for pharmaceutical tablets and capsules
Enhance your production line with versatile bottling...
Tablet counting solution for pharmaceutical industry
Maximize dosing precision and reduce miscounts in high-speed pharmac...
High speed blister packaging for pharmaceuticals
Need efficient packaging with quick format changeovers for various capsul...
High-speed strip packaging for tablets and capsules
Optimize your high-speed pouching operations with precise four-side s...
Pharmaceutical roller compaction solution
Optimize your pharmaceutical tablet production with precision granulation and co...
Capsule filling solution for small to medium batch sizes
Achieve precise and efficient capsule filling up to 3,400 units ...
Capsule filling system for pharmaceutical production
Efficiently fill and lock capsules of various sizes with exceptional...
Tablet and capsule visual inspection system
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Tablet coater for batch sizes up to 250 liters
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Tabletop granulation system for small batches
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Advanced fluid bed for pharmaceutical granulation
Achieve precise granulation and drying for pharmaceutical powders with ...
Fluid-bed granulator for top-spray applications
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Fluid-bed drying and granulation system
Optimize your production line with high-speed batch processing for efficiently dryi...
Liquid capsule filling for r&d and pilot-scale production
Optimize liquid capsule production with a compact machine that...
High-speed capsule filler for large batch production
Achieve higher yields and reduce powder waste with a capsule filling...
Capsule filler for high-speed, dust-free capsule production
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Fluid bed dryer with granulation and coating
Enhance your processing efficiency with a versatile system capable of combini...
Flat-forming blister packager for small production batches
Ideal for pharmaceutical and nutraceutical firms seeking effi...
Tabletop blister packaging for clinical trials
For R&D facilities conducting clinical trials or feasibility studies, ...
Containment blister packaging for highly potent Apis
Ensure operator safety during the blister packaging of highly potent...
Rotary blister packaging for tablets and capsules
Optimize your blister packaging with high-performance rotary forming an...
Blister packaging for solid dosage forms
Optimize your packaging line with high-speed, continuous blister packaging that en...
Capsule band sealer for liquid-filled hard capsules
Seamlessly seal liquid-filled hard capsules to enhance product integr...
Semi-automatic de-blistering solution for Pvc and alu blister packs
Streamline your packaging operations by swiftly rec...
Automatic capsule checkweigher for statistical weight control
Ensure precise weight control of capsules with automatic s...
Capsule de-dusting and polishing system
Ensure precision in capsule production with continuous de-dusting and polishing, en...
Empty capsule sorting system for pharmaceutical manufacturing
Expedite your capsule production with a high-speed system ...
Filled capsule elevator for seamless process integration
Efficiently streamline the transfer of filled capsules across va...
Automated powder and pellet product conveying system
Optimize your encapsulation process effortlessly with this fully aut...
Capsule sorter elevator for encapsulation processes
Ensure uninterrupted encapsulation by efficiently removing defective ...
Metal contamination detection for tablets and capsules
Ensure product integrity by detecting and separating metal particl...
Flat forming and sealing blister packaging solution
Enhance your blister packaging process with a solution that ensures p...
Flat-sealing continuous-motion blister packaging solution
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Fully automatic hard capsule filling machine
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Capsule filling for pharmaceuticals and nutraceuticals
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Online tablet counter inspection system
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Capsule printer for pharmaceutical applications
Experience precise dual-color printing with high-speed efficiency for caps...
H-track ink printing solution for tablets and capsules
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Tablet and capsule ink print and laser marking system
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Tablet and capsule ink printer
Achieve precise and high-speed printing on tablets and capsules, ensuring clear product ident...
Serialization and aggregation inspection system
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Pharmaceutical data management software
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Flat carton serialization station
The packaging lines in the pharmaceutical industry handle several flat cartons. Manual pa...
Blister inspection system
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Cold forming aluminum blister machine for capsules
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Easy to validate capsule filler
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High speed bottle filler with inspection
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Effective Visual Inspection System for Capsules
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Lifter and De-duster for Tablets
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High Speed Visual Inspection System for Tablets
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Contained Visual Inspection System
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Tablet counting machine
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Pharmaceutical bottle unscrambler
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Dessicant inserting machine
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Metal detector for bottles
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Metal detector for tablets and capsules
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Semi-automatic capsule filler
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Automatic filling line for solid doses
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Electronic capsule counter
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Semi-automatic case packer
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Laboratory capsule filler for liquid solutions
A recent important change in the industry is the trend toward providing liq...
Automatic laboratory capsule filler
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Automatic capsule filler
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Industrial capsule checkweigher
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Capsule checkweigher
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Stand-alone aggregation station
The aggregation of pharmaceutical products for tracking purposes is already compulsory in ma...
Serialization coding and labeling equipment
In the pharmaceutical industry, product serialization is the cornerstone of al...
Automatic capsule filler for liquid solutions
Use of liquid filled hard capsules is increasingly popular with today’...
Contained capsule filler
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High-yield capsule filler
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High capacity capsule filler
In the highest volume pharmaceutical production environments, capsule filling needs to be extre...
Scale up capsule filler
For higher production volumes of pharmaceutical capsules, speed, accuracy and reliability of producti...
Entry level capsule filler
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High capacity weight sorter for tablets & capsules
By employing a weight sorter that is fully flexible and able to ha...
Versatile weight sorter for tablets & capsules
Saving costs and improved production efficiencies are possible by opti...
R&D semi-automatic capsule filler
Semi-automatic filling machine suitable to open, fill and close empty hard gelatin capsul...
R&D hard gelatin capsule sealing machine
When encapsulating products at temperatures up to + 80°C, these tend to solidify a...
R&D electronic counter for capsules and tablets
This machine has been designed to offer an ever-precise and reliable count...
R&D automatic capsule filler
Automatic capsule filling machine for powders, pellets, tablets, mini-tablets, capsule in capsu...
R&D capsule orientater
A semi-automatic orienter for capsules with an output speed up to 6000 capsules.
Entry-level blister machine
A start-up solution for contract packing and generics manufacturing with an easy-to-get upgrade ...
Checkweigher for capsules
The new interactive indicator unit allows for even easier use. High-rigidity weighcells have been ...
Checkweigher
A check weigher that is equipped with high speed/high accuracy force balance load cell. It meets stringent accura...
High-sensitivity metal detection system
Highly efficient metal detector with enhanced quality control and reporting capabil...
Entry-level X-ray inspection system
Without compromising on performance, if you need an entry level x-ray inspection system...