Containment capsule filling system for lab and small batch production
Designed to ensure maximum safety in pharmaceutical labs, this capsule filling system offers seamless dosing and containment, allowing for efficient small batch and clinical trial production while protecting personnel from potent active ingredients.

Fills and Seals Capsules with Containment
The Modu-C LS Containment from Harro Höfliger is an engineered-to-order capsule filling machine designed for pharmaceutical applications requiring stringent containment protocols. This system is engineered to handle a variety of materials including powders, tablets, mini-tablets, liquids, and active ingredients, ensuring precise and flexible dosing with its patented trolley system for rapid changeover between processes. Capable of producing up to 25,000 capsules per hour, it supports small batch and pilot productions, ideal for research and development environments, as well as clinical trials.
The machine excels in maintaining operator safety and product integrity using its Modular Advanced Barrier System (MABS), designed for environments with exposure limits as low as OEL < 1 μg/m³. Integration into production lines is facilitated through standard interfaces for seamless IT and network communications, including MES and OPC. It features comprehensive in-line and online weight determination systems, using capacitive AMV sensors for accuracy in dosing even minimal quantities. Compliance with GMP standards, coupled with components like a metal detector and capsule dedusting system, ensures product quality and safety. In terms of maintenance, the machine boasts short setup times, easy operation, and efficient cleaning processes to minimize downtime. Customization options are available for specific production needs, supported by Harro Höfliger's detailed process knowledge and ergonomic design studies.
Benefits
- Enhances user safety and product integrity with advanced barrier containment.
- Facilitates rapid production changes, minimizing downtime with its patented trolley system.
- Maintains precise dosing accuracy through comprehensive weight determination systems.
- Ensures high-quality outputs with integrated capsule dedusting and metal detection.
- Supports GMP compliance and environmental protection with robust containment design.
- Applications
- Pharmaceutical tablets,Pellets,Pharmaceutical powder,Liquids,Active ingredients,Capsules,Mini-tablets
- End products
- Blinded pharmaceutical capsules,Liquid-filled capsules,Clinical trial capsules,Combination capsules with powders and tablets,Small batch specialty capsules,Low-dosage liquid pharmaceuticals,Double-blinded clinical trial tablets,Mini-tablet dosage forms,Sustained-release pellet capsules,Specialty formulated active ingredient capsules
- Steps before
- Purification,Drying,Grinding,Preparation of active ingredients
- Steps after
- Capsule dedusting,Sterilization,Packing,Blinding of tablets and capsules,Quality control
- Input ingredients
- powder,pellets,tablets,mini-tablets,liquid,empty capsules,test material for clinical studies
- Output ingredients
- filled capsules,blinded capsules,double blinded capsules,small batch capsules,combination doses
- Market info
- Harro Hoefliger is known for its expertise in manufacturing custom, engineered-to-order packaging and production equipment, particularly for the pharmaceutical, healthcare, consumer goods, and chemical industries, with a reputation for precision, innovation, and quality engineering solutions.
- Output
- Up to 25,000 capsules/h
- Formats
- All common capsule sizes
- Dosing units
- Drum,dosator,tamping station,pellet,tablet,mini-tablet and liquid
- Changeover time
- Short setup times
- Containment Class
- OEB Class 4 (1-10 μg/m³)
- Pressure measurement
- Differential pressure measurement
- Weight determination
- In-line and online static gross/net inspection,100% gross/net inspection
- Barrier system
- Modular Advanced Barrier System (MABS)
- Ergonomics
- Ergonomic studies performed
- Accessibility
- Optimum accessibility with large operator entries
- Automation level
- PRP function (person reduced production)
- Batch vs. continuous operation
- Batch
- Changeover time
- Minimum setup time
- Cleaning method
- Easy operation and cleaning
- Dosing system change
- Trolley concept for rapid change
- Product protection
- Modular Advanced Barrier System (MABS)
- User protection
- Containment protection for OEL < 1 μg/m³
- Capsule inspection
- Capsule closure inspection and elimination of bad capsules
- Cleanability
- Easy operation and cleaning
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- OEB Class 4
- 1-10 μg/m³
- Dosing trolley system
- Patented,rapid change of dosing
- Peripheral network integration
- Standard interfaces (MES,ActiveDirectory,OPC,…)