Pharmaceutical twin-screw extruder
In the pharmaceutical industry, achieving consistent, high-quality formulations requires precise processing technologies. Traditional manufacturing methods can struggle with issues like product changeover times, large cleanroom space requirements, and handling risks. Modern continuous processing methods are needed to address these challenges efficiently.
Enables continuous and controlled pharmaceutical processing
The Thermo Scientific™ Pharma 24 Twin-Screw Extruder is designed for continuous processing in pharmaceutical research, development, and production. Featuring high free volume screw design and segmented construction of screws and barrel, it ensures minimal ingredient handling and operator exposure. The barrel, designed with pharma-grade steel and a horizontally split structure for easy maintenance, has a main feed port with cooling and seven multi-purpose top feed/vent/injection ports. The machine supports both Hot-Melt Extrusion (HME) and Twin-Screw Granulation (TSG) application sets, with processing capacities up to 20 kg/h for HME and 70 kg/h for TSG. Controlled through a touch screen panel with Siemens PLC, it complies with 21 CFR part 11 and offers four user levels for secure operation.
Benefits
- Reduces cleanroom space requirements
- Consistent and controllable processing
- Minimizes product changeover time
- On-demand production with reduced scale-up risk
- Easy and reliable cleaning