Fluid bed processor for pharmaceutical granulation and coating

Achieve superior granulation and coating of pharmaceutical and nutraceutical products with this fluid bed processor, ensuring optimal particle size distribution and enhanced product uniformity for efficient tablet and capsule production.

Processes and Coats Pharmaceutical Powders and Pellets

The Syntegon Fluid Bed Processor offers pharmaceutical and nutraceutical manufacturers an indispensable solution for drying, granulating, and coating operations. Utilizing the unique Hüttlin Diskjet air distribution system and bottom spray technology, it provides homogeneous mixing and faster drying, catering to tasks like producing paracetamol tablets and vitamin D capsules. With batch capacities ranging from bench-top R&D sizes up to 1,600 kg, it ensures high throughput and versatility across processes. The processor’s three-component nozzle system enhances spray rates and product yield, supporting integration into continuous production lines with ease. Automated features, such as dynamic filtering and cleaning-in-place (CIP) options, meet stringent GMP standards, aligning with energy-efficient practices that lower operational costs. Available in industrial-grade materials to ensure chemical compatibility, this equipment exemplifies precision, compliance, and adaptability.

Benefits

  • Reduces process times by up to 50% through efficient drying and coating.
  • Achieves uniform particle size distribution for improved tablet compression and flow properties.
  • Minimizes product loss with high yield spray technology and dynamic filtering.
  • Supports diverse batch sizes, from R&D to large-scale production, ensuring scalability.
  • Meets GMP standards, ensuring safety and compliance in pharmaceutical manufacturing.

General


Applications
Pharmaceutical tablets,Snacks,Nutraceuticals,Pharmaceutical powder,Pellets,Sweets,Capsules
End products
Delayed-release pellets for proton pump inhibitors,Vitamin d capsules,Coated peanuts,Sugar-coated gummies,Multivitamin capsules,Protein powder supplements,Paracetamol tablets
Steps before
Mixing,High Shear Mixing,Wet Milling
Steps after
Coating,Tablet Compression,Capsule Filling,Packing
Input ingredients
pharmaceutical ingredients,binding agents,neutral pellets,sugar starch,cellulose,tartaric acid,powdered product
Output ingredients
dried granular materials,granules,pellets,multifunctional layers,coated pellets
Market info
Syntegon is known for its expertise in processing and packaging technology, offering innovative solutions for the food and pharmaceutical industries. It has a strong reputation for advanced equipment, sustainability, and customer-oriented service.

Technical Specifications


Batch size
50 g to 1,600 kg
Process Time Reduction
up to 50%
Automation
PROVICON control system
Spray Technology
Bottom spray,top spray,tangential spray
Filtration System
Dynamic filter with internal filter cones
Air Distribution
Hüttlin Diskjet air distribution plate
Particle Size Distribution
Unimodal
Cleaning System
Basic to advanced automated UltraClean system
Spray Rate
High spray rate with bottom spray technology
Nozzle System
Three-component nozzle
CIP Capability
CIP-able metal filters
Heat Transfer Efficiency
High

Operating Characteristics


Working mechanism
Fluid bed drying,granulation,and coating
Batch vs. continuous operation
Batch
Automation level
PROVICON control system
CIP/SIP
Automated cleaning systems
Changeover time
Fast and efficient

Material Compatibility


Abrasion resistance
High
Biological compatibility
Yes
Cleanability
Excellent
Corrosive resistance (e.g. acids)
High
Density/particle size
0.5 kg/l,various particle sizes

Physical Characteristics


Control panel type
PROVICON control system
Batch size
50 g to 1,600 kg
Spray nozzle configuration
Three-component nozzle
Air distribution system
Hüttlin Diskjet air distribution plate
Cleaning system
Advanced automated UltraClean system
Product container
Single product container

Custom Options


Control Panel Type
PROVICON control system
Spraying Options
Bottom spray,top spray,tangential spray
Batch Size Flexibility
0.05 kg to 1,500 kg
Cleaning System
Advanced automated UltraClean system
Filter Type
Dynamic filter with internal filter cones
Container Integration
One product container for multiple processes
Fluid Bed Technology
Hüttlin Diskjet air distribution plate