Triple combi filling and stoppering system for vials and ampoules
Optimize your liquid formulation process with a versatile system designed for precise, high-speed filling and stoppering of vials, ampoules, and cartridges, ensuring product integrity and compliance with stringent industry standards.

Fills, Stopes, and Weighs Liquid Pharmaceuticals
The Triple Combi Filling Stoppering Machine from Snowbell Machines offers a seamless solution for pharmaceutical and biotech manufacturers looking to enhance precision and efficiency in liquid formulation processes. This state-of-the-art machine combines filling, stoppering, and in-line check weighing into a single integrated system, significantly optimizing the production line. Utilizing robotic and servo-based controls, it supports high-speed, automated operations while maintaining product integrity and sterility. Perfectly suited for a range of applications such as vaccines, diagnostic reagents, and eye drops, the machine ensures compliance with 21 CFR Part 11 standards. It integrates smoothly with R&D and final conditioning departments, and its design incorporates robust SCADA systems for advanced process monitoring and control. With a focus on easy integration and minimal downtime, it provides pharmaceutical manufacturers with reliable engineering support and the flexibility to handle a variety of liquid product types.
Benefits
- Enhances production efficiency with integrated filling, stoppering, and weighing.
- Reduces labor intervention through automated, servo-based operation.
- Ensures product integrity and regulatory compliance with 21 CFR Part 11 standards.
- Minimizes contamination risk with robotic controls for precise operations.
- Facilitates seamless integration into existing production lines, boosting overall process reliability.
- Applications
- Biopharmaceuticals,Ophthalmic solutions,Liquid formulations,Pharmaceuticals
- End products
- Pain relief ampoules,Injectable medications,Antibacterial ampoules,Eye drops,Insulin cartridges,Sterile saline solutions,Vaccine vials,Diagnostic reagents
- Steps before
- Purification,Drying
- Steps after
- Stoppering,Sterilization,Packing
- Input ingredients
- Vials,Ampoules,PFS (Pre-filled syringes)
- Output ingredients
- Filled and stoppered vials,Filled and stoppered ampoules,Filled and stoppered pre-filled syringes
- Market info
- Automation
- Servo-based control system
- Compliance
- 21CFR part 11 / SCADA system
- Check Weighing System
- Non-destructive in-line check weighing system
- Control Type
- Robotic Controls
- Automation level
- Robotic Controls / Servo based control system
- Batch vs. continuous operation
- Batch
- Non-destructive check weighing
- In-line
- Control system
- SCADA / 21CFR part 11 compliant
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Machine footprint
- Compact design
- Control panel type
- Touchscreen panel
- Discharge method
- Automated stoppering
- Control panel type
- Robotic Controls
- Integration with existing systems
- SCADA system