Triple combi filling and stoppering system for vials and ampoules

Optimize your liquid formulation process with a versatile system designed for precise, high-speed filling and stoppering of vials, ampoules, and cartridges, ensuring product integrity and compliance with stringent industry standards.

Fills, Stopes, and Weighs Liquid Pharmaceuticals

The Triple Combi Filling Stoppering Machine from Snowbell Machines offers a seamless solution for pharmaceutical and biotech manufacturers looking to enhance precision and efficiency in liquid formulation processes. This state-of-the-art machine combines filling, stoppering, and in-line check weighing into a single integrated system, significantly optimizing the production line. Utilizing robotic and servo-based controls, it supports high-speed, automated operations while maintaining product integrity and sterility. Perfectly suited for a range of applications such as vaccines, diagnostic reagents, and eye drops, the machine ensures compliance with 21 CFR Part 11 standards. It integrates smoothly with R&D and final conditioning departments, and its design incorporates robust SCADA systems for advanced process monitoring and control. With a focus on easy integration and minimal downtime, it provides pharmaceutical manufacturers with reliable engineering support and the flexibility to handle a variety of liquid product types.

Benefits

  • Enhances production efficiency with integrated filling, stoppering, and weighing.
  • Reduces labor intervention through automated, servo-based operation.
  • Ensures product integrity and regulatory compliance with 21 CFR Part 11 standards.
  • Minimizes contamination risk with robotic controls for precise operations.
  • Facilitates seamless integration into existing production lines, boosting overall process reliability.

General


Applications
Biopharmaceuticals,Ophthalmic solutions,Liquid formulations,Pharmaceuticals
End products
Pain relief ampoules,Injectable medications,Antibacterial ampoules,Eye drops,Insulin cartridges,Sterile saline solutions,Vaccine vials,Diagnostic reagents
Steps before
Purification,Drying
Steps after
Stoppering,Sterilization,Packing
Input ingredients
Vials,Ampoules,PFS (Pre-filled syringes)
Output ingredients
Filled and stoppered vials,Filled and stoppered ampoules,Filled and stoppered pre-filled syringes
Market info

Technical Specifications


Automation
Servo-based control system
Compliance
21CFR part 11 / SCADA system
Check Weighing System
Non-destructive in-line check weighing system
Control Type
Robotic Controls

Operating Characteristics


Automation level
Robotic Controls / Servo based control system
Batch vs. continuous operation
Batch
Non-destructive check weighing
In-line
Control system
SCADA / 21CFR part 11 compliant

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Machine footprint
Compact design
Control panel type
Touchscreen panel
Discharge method
Automated stoppering

Custom Options


Control panel type
Robotic Controls
Integration with existing systems
SCADA system