Rotary vial filling and stoppering

Ensure precise liquid formulations and lyophilized product consistency with a high-speed rotary system designed for efficient filling, stoppering, and capping processes. Ideal for handling parenteral solutions and maintaining aseptic conditions throughout production.

Fills, Stopers, and Caps Vials Efficiently

The STERY-SA and CAPSY-SA from Marchesini Group are rotary vial filling and capping machines crafted for aseptic processing in pharmaceutical and biotech sectors. They stand out by combining precise rotary filling, stoppering, and capping into a streamlined process, suitable for both liquid and lyophilized parenteral products. These machines address the efficiency demands of high-throughput environments, capable of handling up to 3,600 pieces per hour with options for full or partial rubber stoppering.

The STERY-SA employs rotary piston or peristaltic pumps for versatile filling options, ensuring accurate dose control. Designed to easily integrate under oRABS, cRABS, and Isolators, the system offers seamless alignment with existing aseptic facilities.

Automation is enhanced with PLC controls and integrated pre-feeders for stoppers and alu-caps, ensuring compact arrangement and reliable operation. Constructed with robust mechanical assembly, both models deliver reliable long-term performance. The alu-capping function can be installed directly on the filler in a monoblock configuration or as a standalone unit, providing flexible customization to suit specific line requirements.

Compliant with GMP standards, these machines facilitate high sanitary standards with easy-to-clean surfaces, and options for automated clean-in-place (CIP) capabilities. Marchesini offers extensive engineering support and customization, allowing configurations to meet unique production needs.

Benefits

  • Ensures precise product dosing and minimizes waste with flexible filling options.
  • Integrates smoothly into existing aseptic environments, enhancing operational efficiency.
  • Increases production speed with high throughput of up to 3,600 vials per hour.
  • Minimizes labor requirements through automated stopper and cap feeding systems.
  • Meets strict GMP standards, promoting pharmaceutical-grade hygiene and safety.

General


Applications
Liquid formulations,Injectable solutions,Lyophilized products,Biopharmaceuticals,Parenteral products,Pharmaceuticals
End products
Heparin sodium injectable,Meropenem lyophilized,Vaccines,Immunoglobulin g infusions,Monoclonal antibodies,Omeprazole lyophilized powder,Rituximab,Epoetin alfa,Doxorubicin hydrochloride,Albumin solutions,Insulin glargine,Ceftriaxone sodium
Steps before
Washing,Sterilizing
Steps after
Inspection,Labelling,Secondary Packaging,End of Line Packaging
Input ingredients
small volume parenteral,large volume vials,liquid products,lyo products,rubber stoppers,alu-caps,vials 2R
Output ingredients
filled vials,stoppered vials,capped vials,vials up to 500 ml,output pieces per hour: 3,600
Market info
Marchesini is renowned for manufacturing high-quality packaging machinery for the pharmaceutical and cosmetics industries, offering innovative, customized solutions with advanced automation and technology.

Technical Specifications


Filling System
Rotary Piston Pumps / Peristaltic pumps
Output Capacity
3,600 Pieces/h
Vial Size Range
2R / 500 ml
Stoppering Type
Full or Partial Rubber Stoppering
Automation
oRABS,cRABS,Isolator Integration
Weight Control
100% IPC Available
Alu-capping Station
Integrated / Dedicated Machine
Stopper and Alu-caps Pre-feeders
Integrated on Board

Operating Characteristics


Automation level
Manual / PLC / SCADA
Integrated steps
Filling and Alu-capping
Batch vs. continuous operation
Batch / Inline Continuous
Cleaning method
CIP / Manual
CIP/SIP
CIP 121°C / SIP 135°C
Energy efficiency
0.5–2 kWh/kg moisture

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Machine footprint
Compact
Integration capability
oRABS,cRABS,Isolator
Type of filling system
Rotary Piston Pumps / Peristaltic pumps
Vial size
2R to 500 ml
Alu-capping configuration
Monoblock or separate
Stoppering type
Full or partial rubber

Custom Options


Control panel type
Rotary Piston Pumps / Peristaltic Pumps
Integration Possibilities
oRABS / cRABS / Isolator
Configuration Options
Alu-capping station on board / CAPSY-SA version
Compact arrangement
Stopper and Alu-caps pre-feeders and sorting systems integrated