Pharmaceutical separator for high solid contents

Ensure optimal purity in biopharmaceutical processing with a separator designed for handling high solid content and shear-sensitive products, guaranteeing gentle yet efficient separation critical to maintaining product integrity in cell therapies and vaccine formulations.

Separates and Purifies Biopharmaceutical Liquids

The GEA Pharma Separator Pure is engineered specifically for the pharmaceutical and biotech industries, providing a solution for the separation and purification of high-value, shear-sensitive products such as vaccines, monoclonal antibodies, and cell therapies. This centrifugal separator operates with a unique hydrohermetic feed design, which minimizes product stress by gently accelerating the liquid within the filled bowl, ensuring optimal yield and quality. The system offers seamless adjustment capabilities during production, allowing for precision handling of diverse solid and liquid formulations without the need for machine modifications.

Designed to meet the demands of continuous, high-speed operations, the GEA Pharma Separator Pure integrates effortlessly into existing production lines with its optimized plug-and-produce pharma skids. Available in various bowl sizes to accommodate different process capacities, the equipment is also equipped with an Integrated Direct Drive (IDD) system to ensure high cleanroom class standards while reducing mechanical wear.

Manufactured to comply with industry regulations, the separator features automatic Clean-in-Place (CIP) systems, ASME-BPE compliance options, and gap-free welded disk spacers, enhancing both cleanability and validation processes. Its skid design is tailored to provide maximum safety and yield, supporting customization and engineering support to address specific process requirements.

Benefits

  • Enhances product quality with gentle handling of shear-sensitive formulations.
  • Increases operational flexibility through seamless capacity adjustments during production.
  • Ensures regulatory compliance with integrated CIP systems and ASME-BPE options.
  • Minimizes maintenance needs with the efficient Integrated Direct Drive technology.
  • Optimizes cleanroom environments by preventing emissions with a closed motor housing.

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General


Applications
Biopharmaceuticals,Shear sensitive products,Liquid formulations,Pharmaceutical processing
End products
Blood plasma products,Monoclonal antibodies,Insulin formulations,Injectable solutions,Vaccine formulations,Cell therapies
Steps before
Filtration,Mixing,Preparation
Steps after
Sterilization,Packaging,Concentration
Input ingredients
Output ingredients
Market info
GEA is known for its expertise in engineering innovative and sustainable equipment and solutions, focusing on sectors such as food, beverages, pharmaceuticals, and energy, with a reputation for quality, efficiency, and advanced technological applications in industrial processing.

Technical Specifications


Capacity
5 to 10 vol% (C type),up to 35 vol% (X type)
Bowl sizes
Four different sizes available
Automation
Automatic CIP
Drive type
Integrated Direct Drive (IDD)
Motor Cooling
Water cooled motor
Shear Force Handling
No shear forces
Flow Rate Adjustment
Seamless adjustment during production
Hydrohermetic Inlet
Patented
Plug,Produce Skid Design
Optimized for standard and custom requirements
Yield Optimization
Flexicon nozzle bowl
Emission Control
Closed housing prevents emissions
Process Adaptability
3-in-1 convertibility (X type)

Operating Characteristics


Working Mechanism
Nozzle Separator
Automated CIP
Automatic
Batch vs. Continuous Operation
Continuous
Integration Flexibility
Plug,Produce
Automation Level
Integrated Direct Drive (IDD)
Shear Sensitive Handling
Patented Hydrohermetic Inlet
Capacity Range
Multiple Bowl Sizes
Changeover Capabilities
Seamlessly Adjustable
Yield Optimization
Flexicon Nozzle Bowl
Cleanability
Optimum Cleanability Features
Emission Control
Closed Housing for Cleanroom Use

Material Compatibility


Cleanability
Automatic CIP
Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm


ASME BPE
Available as an option

Physical Characteristics


Machine Footprint
N/A
Bowl Size
Four different bowl sizes
Skid Design
Optimized Skid Design
Compact Footprint
Optimized for space efficiency
Discharge Method
Automatic CIP
Hydrohermetic Inlet
Patented design
Nozzle Bowl
Flexicon Nozzle Bowl

Custom Options


Cleanability features
Automatic CIP
Validation easiness
Quick and easy validation process
Hydrohermetic inlet design
Patented design
Capacity options
Four bowl sizes available
Nozzle bowl adaptability
GEA flexicon nozzle bowl
Integrated Direct Drive (ID)
State-of-the-art IDD Drive
ASME BPE
Available as option
Disk spacers
Patented gap-free welded as option