Automatic chromatography column for biopharmaceutical separation

Ensure high-purity monoclonal antibodies and herbal extracts with precise control and reliability in your biopharmaceutical separation process.

Purifies Biopharmaceuticals and Diagnostic Reagents

Truking Technology’s AutoColumn AC series and EasyColumn series offer sophisticated solutions for biopharmaceutical and diagnostic reagent purification. The AutoColumn AC features a patented structural mechanics design, utilizing a double ball screw transmission for enhanced capacity and compactness, alongside a fluid simulation distributor ensuring high column efficiency. It supports automatic operations with a user-friendly wizard mode packing station and meets cGMP requirements, making it ideal for monoclonal antibody and freeze-dried vaccine production. The EasyColumn series provides a manual alternative with a unique lever-driven sealing system and 316L stainless steel construction for durability and corrosion resistance. Both series are equipped for optimal integration, ensuring streamlined processes for pharmaceutical and biotech industries.

Benefits

  • Enhances purification efficiency, ensuring high-purity bioproducts.
  • Minimizes labor through automated packing and operation modes.
  • GMP-compliance safeguards product quality and regulatory adherence.
  • Stainless steel construction increases lifespan in corrosive settings.
  • Compact design optimizes facility space, improving process flow.

General


Applications
Pre-filled syringe products,Injectable medicines,Oral liquid preparations,Lyophilized products,Soft bag solutions,Biopharmaceuticals,Traditional chinese medicine,Ampoule products,Bfs production,Diagnostic reagents
End products
Insulin pre-filled syringes,Freeze-dried vaccines,Intravenous antibiotics,Monoclonal antibodies,Cough syrup,Iv saline solutions,Single-dose eye drops,Herbal extracts,Covid-19 test kits,Injectable vitamin ampoules
Steps before
Purification,Extraction,Concentration,Reaction Tank,Crystallization
Steps after
Sterilization,Packing,Loading,Unloading,Inspection
Input ingredients
biological drugs,resin,slurry
Output ingredients
purified biological drugs
Market info
Truking is known for manufacturing engineered-to-order pharmaceutical equipment, specializing in liquid and solid preparation systems. They have a strong reputation for innovation and quality in the pharmaceutical machinery sector.

Technical Specifications


Column Diameter Range
100 to 450 mm
Automation
Fully automated wizard mode
Column Efficiency
High column efficiency with good symmetry and reproducibility
Sealing
Reliable patented column head sealing
Positive Pressure Packing Method
Prevents bubble generation,improves resin utilization
Material
316L stainless steel
Sieve Mounting Structure
Center welded fixing ring,easy air exhaust
U-shaped Sealing Ring
Easy replacement,low cost
Disassembly Structure
Small footprint,improved cleaning efficiency
Automation Features
Patented automatic nozzle,fluid simulation distributor
Column Head Movement
Deflection structure,easier maintenance
Column Head Sealing Type
Lever drive principle
Valve Type
Four-way valve for leakage protection
Temperature Resistance
Resistant to temperature changes
Fluid Distribution
Optimal effect with fluid simulation testing
Verification Documents
cGMP compliant
Packing Station Memory Function
Meets loading requirements for all column ranges

Operating Characteristics


Automation level
Manual / PLC / SCADA
Batch vs. continuous operation
Batch / Inline Continuous
CIP/SIP
CIP 121°C / SIP 135°C
Cleaning method
CIP / Manual
Energy efficiency
0.5–2 kWh/kg moisture

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Physical Characteristics


Machine footprint
Compact design
Tank shape
Column with inclined strut
Tank size
Diameter 100–450 mm
Weight
Lighter weight due to design
Size
Smaller size,lower height
Footprint
Small footprint
Discharge method
Patented column disassembly structure

Custom Options


Control panel type
Touchscreen / LCD
Integration possibilities
SCADA / HMI / PLC systems
Compact footprint
Yes
Discharge method
Automatic / Manual
Disassembly feature
Patented disassembly design for easy cleaning