High pressure homogenizer for cell disruption and nanoemulsions
In pharmaceutical and biotechnology sectors, achieving uniform particle size reduction and effective cell disruption is critical for product stability and bioavailability. Traditional methods often fail to provide the necessary consistency and fine control required at the research and pilot production stages.

Ensure precise nanoemulsions and consistent cell disruption
The DeBEE 2000 by Pion is a high pressure homogenizer that bridges the gap between research and pilot scale production. This model is capable of advanced process customization, allowing users to easily replicate established processing protocols. The equipment supports various applications including micro and nanoemulsions, efficient cell disruption, and uniform particle size reduction, resulting in small and consistent liposomes. It is ideal for industries requiring more precise control over product formulations to improve bioavailability and product stability. The system is cGMP, CE, and CFR 21 Part 11 compliant with features such as electronic signatures, user management, audit trail, data collection, and SCADA integration. The unit is also designed with Clean in Place (CIP) capability for easy maintenance, making it an effective tool for scaling up from R&D to pilot production.
Benefits
- Customizable for advanced process optimization
- Guaranteed scalability from R&D to pilot production
- cGMP, CE, and CFR 21 Part 11 compliant
- Supports various applications like nanoemulsions and cell disruption
- Clean in Place (CIP) for easy maintenance