Filling and closing system for ampoules
Ensure precision and efficiency in your aseptic fill-finish operations with a compact system that integrates filling and closing of ampoules seamlessly, reducing contamination risks and optimizing throughput.
Fills and Seals Ampoules and Vials
The Type 502/503 machines from BAUSCH Advanced Technology Group are specialized aseptic fill-finish solutions designed for high-speed filling and sealing of ampoules and vials. These machines utilize a two-piece, valveless dosing pump system for precise filling accuracy of up to +/- 0.05%, critical for maintaining product integrity in pharmaceutical and biopharmaceutical applications. With a maximum output of 6,000 containers per hour, they are optimized for continuous operations under laminar flow, RABS, or isolator setups. The use of a transport star wheel ensures smooth and continuous transfer of containers, while the rotational feature minimizes foaming and enhances uniform heating of ampoule stems. Vials are securely closed with rubber stoppers fed from a vibrating bowl, ensuring a tight seal. Integrable into existing production lines or as stand-alone units, these machines support GMP and FDA compliance, offering reliable performance for sterile liquid formulations, including vaccine vials and biologic drug containers.
Benefits
- Enhances production efficiency with high-speed output of up to 6,000 containers per hour.
- Ensures precision dosing with an accuracy of up to +/- 0.05%, maintaining product quality.
- Integrates seamlessly into existing production lines, supporting continuous and standalone operations.
- Minimizes contamination risk with optimized operation under laminar flow, RABS, or isolator environments.
- Complies with GMP and FDA standards, ensuring regulatory adherence for pharmaceutical manufacturing.
- Applications
- Biopharmaceuticals,Aseptic fill-finish packaging,Liquid formulations,Pharmaceuticals
- End products
- Aseptic iv bags,Injectable solutions,Liquid pharmaceuticals,Sterile ampoules,Biologic drug vials,Vaccine vials
- Steps before
- Purification,Drying,Component Preparation
- Steps after
- Sterilization,Packing
- Input ingredients
- ampoules,vials,rubber stoppers
- Output ingredients
- filled ampoules,closed ampoules,sealed vials
- Market info
- Bausch Group is known for its precision engineering and manufacturing of custom industrial equipment, specializing in engineered-to-order solutions for various industries, prioritizing quality, innovation, and client-specific needs.
- Output Capacity
- 6,000 containers/hr
- Filling Accuracy
- ± 0.05%
- Transport System
- Transport star wheel
- Dosing Pump Type
- Two-piece,valveless
- Closure Method
- Rubber stoppers
- Operation Options
- Stand-alone or integrated
- Foaming Minimization
- Continual rotation of containers
- Working mechanism
- Filling and closing of ampoules
- Integrated steps
- Filling and sealing
- Automation level
- High (uses transport star wheel)
- Batch vs. continuous operation
- Continuous,max output 6,000/hr
- Foaming control
- Continuous rotation of containers
- Temperature control
- Evenly heated ampoule stem
- Cleaning method
- Optimized for laminar flow
- Biological compatibility
- Aseptic applications
- Cleanability
- Suitable for use under laminar flow,RABS,or isolator conditions
- Corrosive resistance (e.g. acids)
- Stainless steel components
- Density/particle size
- Product handling designed to minimize foaming
- Compact footprint
- Compact unit
- Integrated into production line
- Stand-alone or integrated
- Transport system
- Transport star wheel
- Rotation system
- Continuous rotation
- Vial closing system
- Rubber stoppers with vibrating bowl