Rotary filler for pharmaceutical vials
Optimize precision and efficiency in fill-finish operations with a rotary system designed to handle high-speed filling, stoppering, and crimping of sterile liquid vials, ensuring compliance with stringent pharmaceutical production standards.
Fills and Seals Vials and Bottles
The Hull i-Dositecno Microline Rotary Filler is a robust solution for pharmaceutical manufacturers requiring precision in filling and sealing sterile liquid products. It integrates smoothly into processing lines, handling applications such as filling, stoppering, tip placement, pump inserting, crimping, and closing. This system supports high-speed operations, processing up to 6,000 units per hour. It accommodates stainless steel or ceramic rotary piston pumps, or peristaltic pumps, ensuring flexibility for various liquid formulations. Built with stainless steel AISI 304 construction, all components comply with cGMP and FDA standards, with optional high containment solutions for handling sensitive products.
Automation includes PLC control with servo-driven movements, enabling seamless integration with vial washers, depyrogenation tunnels, freeze dryers, and more. The equipment is 21 CFR Part 11 compliant, offering a complete audit trail, while laminar flow systems and isolators maintain sterility. The user-friendly design features an intuitive servo-controlled star wheel, with CIP/SIP compatibility for effortless, sterile cleaning. Customization options include different pump configurations and containment solutions, backed by thorough documentation and engineering support.
Benefits
- Maximizes production efficiency with up to 6,000 units per hour capacity.
- Ensures sterility through laminar flow systems and full CFR Part 11 compliance.
- Enhances flexibility with interchangeable pump options for diverse liquid formulations.
- Simplifies cleaning and maintenance with CIP/SIP compatibility.
- Integrates seamlessly into existing lines for comprehensive pharmaceutical manufacturing solutions.
- Applications
- Pharmaceutical fill-finish,Ophthalmic containers,Liquid formulations,Injectable products
- End products
- Insulin vials,Sterile intravenous fluids,Sterile antibiotic vials,Ophthalmic eye drops,Vaccine vials
- Steps before
- Vial Washing – Internal/External,Depyrogenation,Pre-sterilization,Cleanroom unscrambling
- Steps after
- Stoppering,Crimping,Capping,Gas Flushing,External Vial Washing,Tray Loading,Sterilization
- Input ingredients
- bottles,vials,pre-sterilized glass,ophthalmic containers,vials for filling,H2O2 for sterilization
- Output ingredients
- filled vials,stoppered vials,capped vials,crimped vials,weighed vials,vials with high containment solution
- Market info
- SP Scientific is known for manufacturing high-quality freeze dryers, laboratory thermal control systems, and aseptic processing equipment, catering primarily to the pharmaceutical, biotech, and life sciences sectors with reputation for precision engineering and reliable performance.
- Speed
- Up to 6000 vials/hour
- Filling Volume
- 1 ml – 500 ml
- Material Construction
- Stainless steel AISI 304,AISI 316L
- Sterilization Method
- CIP/SIP,Autoclave,H2O2
- Compliance
- 21 CFR Part 11
- Automation
- Semi-automatic / Automatic
- Pump Type
- Rotary piston / Peristaltic
- Output Capacity
- Maximum output 3000/hour (single)
- 6000/hour (double)
- Head Capacity
- Up to 4 heads
- Control System
- Servo-driven,Axes controlling system
- Nozzle Rugosity
- Ra,lt
- 0.5
- Weight Detection
- 100% vials weighing
- Container Type Compatibility
- Vials and syringes
- Stopper Introduction
- Servo pick and place
- Working mechanism
- Rotary filling,stoppering,crimping
- Integrated steps
- Filling,stoppering/tip placement,pump inserting,crimping
- Batch vs. continuous operation
- Batch
- CIP/SIP
- CIP/SIP capable,H2O2 sterilizable
- Automation level
- Semi-automatic to automatic
- Cleaning method
- Inline sterilization (CIP/SIP or by autoclave)
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Compatibility with H2O2 sterilization
- Yes
- Compatibility with stainless steel
- AISI 304,AISI 316L
- Compatibility with ceramic components
- Yes
- High Containment
- Yes
- GMP Compliance
- Yes
- FDA compliance
- Yes
- CFR21 compliance
- Yes
- Machine Footprint
- Compact
- Material
- Stainless Steel AISI 304
- Contact Material
- AISI 316L
- Flow Configuration
- Rotary Filling
- Number of Filling Heads
- Up to 4
- Process Compatibility
- Vials and bottles up to 6000 u/h
- Pump Options
- Stainless steel or ceramic rotary piston,peristaltic pumps
- Integration Capability
- Vial washer,depyrogenation tunnel,etc.
- Build Standard
- cGMP,FDA
- Debagging Options
- Manual / Semi-automatic
- Delidding Options
- Manual / Semi-automatic / Automatic
- Filling Pump Type
- Stainless Steel Rotary / Ceramic Rotary / Peristaltic
- Sterilization Method
- CIP/SIP / H₂O₂ / Autoclave
- Control System
- Servo-motor / Axes Controlling System
- Vial Type Compatibility
- Non-pre-sterilized / Pre-sterilized
- Containment Solution
- RABs / Isolator