Sterile filtration for cell culture media

Ensure sterility in cell culture and bioprocessing with advanced filtration solutions, eliminating microbial contamination while preserving the integrity of sensitive biological components across various production stages.

Filters and Sterilizes Liquid Media and Solutions

Millipore® Sterile Filters offer reliable filtration solutions across various industries, from pharmaceuticals to diagnostics. Designed for critical applications, these devices provide robust filtration and sterilization to maintain product purity. Featuring pressure-driven and vacuum filtration units, they accommodate bench-top operations with capacities up to 20 liters, ensuring efficiency in both small- and large-scale processes. Options include low protein-binding Millipore Express® PLUS PES membranes, ideal for fast flow rates, and Durapore® PVDF membranes for minimal protein interaction. These filters integrate seamlessly into existing production lines, meeting stringent GMP and FDA standards, and offer customizable configurations to suit specific processing needs. Quick-connect features and ergonomic designs simplify set-up and maintenance, enhancing laboratory workflow and reducing downtime. Suitable for diverse applications such as monoclonal antibody production, cell media supplementation, and environmental testing, Millipore® Sterile Filters ensure high-quality outcomes with every use.

Benefits

  • Ensures high product purity and safety by effectively removing contaminants through precise filtration.
  • Enhances operational efficiency with quick-connect designs for seamless integration and swift maintenance.
  • Minimizes protein loss and ensures rapid processing, thanks to low protein-binding membrane options.
  • Meets strict regulatory requirements, supporting GMP and FDA compliance for pharmaceutical workflows.
  • Adapts to various processing demands with customizable configurations, ensuring versatility across applications.

General


Applications
Food,Clinical research,Mabs development,Microbiological testing,Molecular biology,Protein biology,Environmental testing,Cell culture media,Biopharmaceuticals,Beverage testing,Diagnostics,Cannabis testing,Manufacturing,Mrna development,Pharmaceuticals
End products
Carbonated beverages,Fruit juice concentrates,Dna and rna samples,Environmental test kits,Cannabis oil extracts,Cell media supplements,Microbiological culture media,Monoclonal antibodies (mabs),Clinical test kits,Protein solutions,Injectable drugs,Genetic material for mrna vaccines,Diagnostic assays,Pathogen detection kits
Steps before
Media Preparation,Buffer Preparation,Sample Collection,Reagent Mixing
Steps after
Storage,Analytical Testing,Cell Culture,Mammalian Cell Culture,3D Cell Culture
Input ingredients
cell culture media,buffers,biological samples,proteinaceous samples,serum-supplemented media,aqueous solutions
Output ingredients
clarified solutions,sterile cell culture media,filtered biological samples,sterile proteinaceous samples,filtered aqueous solutions
Market info
Merck is known for its focus on life sciences, healthcare, and performance materials, offering products like pharmaceuticals, biopharmaceuticals, and high-tech materials. It has a strong reputation for innovation and quality in these sectors.

Technical Specifications


Filter membrane material
Polyethersulfone (PES),PVDF,Nylon mesh
Pore size
0.22 µm,0.45 µm
Capacity
,lt50mL,,lt1L,,lt2L,5-10L,,lt20L
Volume capacity sizes
10 L,20 L
Membrane types
Millipore Express®PLUS PES,Durapore®PVDF
Pressure-driven filtration
Yes
Filtration system
Vacuum,pressure-driven
Compatibility
50 mL centrifuge tube,vacuum-rated bottles
Usability
Quick Release,Eco-friendly design
Flow rate
Fastest flow with low protein binding

Operating Characteristics


Filtration Method
Pressure-driven / Vacuum / Gravity
Membrane Options
PES / PVDF / Nylon Mesh
Volume Capacity
<50mL to <20L
Sterilization Compatibility
Sterilization through filtration
Pore Size Range
0.22 µm / 0.45 µm
Environmental Impact
Reduced plastic waste
Workflow Integration
Compatible with syringes,pumps,and pressure vessels
Application-Specific Design
Cell culture media and buffer filtration

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Filter membrane type
PES,PVDF,Nylon

Physical Characteristics


Filter size
50 mL,<1L,<2L,5-10L,<20L
Filter type
Steriflip®,Stericup®Quick Release,Stericup®E,Sterivex™,Stericap™,Steripak™
Membrane type
PES,PVDF,Nylon mesh
Filter unit design
Bottle-top,pressure-driven,vacuum filtration

Custom Options


Membrane Type
Millipore Express PES,Durapore PVDF,Nylon Mesh
Filter Volume Range
<50mL,<1L,<2L,5-10L,<20L
Integration Possibilities
Syringes,Peristaltic Pumps,Pressure Vessels
Outlet Connections
Various outlet connections
Pressure-Driven Filter Units
Sterivex,Steripak
ECO-Friendly Design
Stericup E
Filter Membrane Types
Express PES,Durapore PVDF
Filter Sizes
0.22 µm,0.45 µm
Volume Capacity
Up to 2L,Up to 10L,Up to 20L
Filter Device Types
Stericup Quick Release,Stericup E,Sterivex
Bottle Compatibility
20 to 67 mm diameter bottles
Membrane Options
Polyethersulfone (PES),Polyvinylidene fluoride (PVDF)