Sterile filtration for cell culture media
Ensure sterility in cell culture and bioprocessing with advanced filtration solutions, eliminating microbial contamination while preserving the integrity of sensitive biological components across various production stages.

Filters and Sterilizes Liquid Media and Solutions
Millipore® Sterile Filters offer reliable filtration solutions across various industries, from pharmaceuticals to diagnostics. Designed for critical applications, these devices provide robust filtration and sterilization to maintain product purity. Featuring pressure-driven and vacuum filtration units, they accommodate bench-top operations with capacities up to 20 liters, ensuring efficiency in both small- and large-scale processes. Options include low protein-binding Millipore Express® PLUS PES membranes, ideal for fast flow rates, and Durapore® PVDF membranes for minimal protein interaction. These filters integrate seamlessly into existing production lines, meeting stringent GMP and FDA standards, and offer customizable configurations to suit specific processing needs. Quick-connect features and ergonomic designs simplify set-up and maintenance, enhancing laboratory workflow and reducing downtime. Suitable for diverse applications such as monoclonal antibody production, cell media supplementation, and environmental testing, Millipore® Sterile Filters ensure high-quality outcomes with every use.
Benefits
- Ensures high product purity and safety by effectively removing contaminants through precise filtration.
- Enhances operational efficiency with quick-connect designs for seamless integration and swift maintenance.
- Minimizes protein loss and ensures rapid processing, thanks to low protein-binding membrane options.
- Meets strict regulatory requirements, supporting GMP and FDA compliance for pharmaceutical workflows.
- Adapts to various processing demands with customizable configurations, ensuring versatility across applications.
- Applications
- Food,Clinical research,Mabs development,Microbiological testing,Molecular biology,Protein biology,Environmental testing,Cell culture media,Biopharmaceuticals,Beverage testing,Diagnostics,Cannabis testing,Manufacturing,Mrna development,Pharmaceuticals
- End products
- Carbonated beverages,Fruit juice concentrates,Dna and rna samples,Environmental test kits,Cannabis oil extracts,Cell media supplements,Microbiological culture media,Monoclonal antibodies (mabs),Clinical test kits,Protein solutions,Injectable drugs,Genetic material for mrna vaccines,Diagnostic assays,Pathogen detection kits
- Steps before
- Media Preparation,Buffer Preparation,Sample Collection,Reagent Mixing
- Steps after
- Storage,Analytical Testing,Cell Culture,Mammalian Cell Culture,3D Cell Culture
- Input ingredients
- cell culture media,buffers,biological samples,proteinaceous samples,serum-supplemented media,aqueous solutions
- Output ingredients
- clarified solutions,sterile cell culture media,filtered biological samples,sterile proteinaceous samples,filtered aqueous solutions
- Market info
- Merck is known for its focus on life sciences, healthcare, and performance materials, offering products like pharmaceuticals, biopharmaceuticals, and high-tech materials. It has a strong reputation for innovation and quality in these sectors.
- Filter membrane material
- Polyethersulfone (PES),PVDF,Nylon mesh
- Pore size
- 0.22 µm,0.45 µm
- Capacity
- ,lt50mL,,lt1L,,lt2L,5-10L,,lt20L
- Volume capacity sizes
- 10 L,20 L
- Membrane types
- Millipore Express®PLUS PES,Durapore®PVDF
- Pressure-driven filtration
- Yes
- Filtration system
- Vacuum,pressure-driven
- Compatibility
- 50 mL centrifuge tube,vacuum-rated bottles
- Usability
- Quick Release,Eco-friendly design
- Flow rate
- Fastest flow with low protein binding
- Filtration Method
- Pressure-driven / Vacuum / Gravity
- Membrane Options
- PES / PVDF / Nylon Mesh
- Volume Capacity
- <50mL to <20L
- Sterilization Compatibility
- Sterilization through filtration
- Pore Size Range
- 0.22 µm / 0.45 µm
- Environmental Impact
- Reduced plastic waste
- Workflow Integration
- Compatible with syringes,pumps,and pressure vessels
- Application-Specific Design
- Cell culture media and buffer filtration
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Filter membrane type
- PES,PVDF,Nylon
- Filter size
- 50 mL,<1L,<2L,5-10L,<20L
- Filter type
- Steriflip®,Stericup®Quick Release,Stericup®E,Sterivex™,Stericap™,Steripak™
- Membrane type
- PES,PVDF,Nylon mesh
- Filter unit design
- Bottle-top,pressure-driven,vacuum filtration
- Membrane Type
- Millipore Express PES,Durapore PVDF,Nylon Mesh
- Filter Volume Range
- <50mL,<1L,<2L,5-10L,<20L
- Integration Possibilities
- Syringes,Peristaltic Pumps,Pressure Vessels
- Outlet Connections
- Various outlet connections
- Pressure-Driven Filter Units
- Sterivex,Steripak
- ECO-Friendly Design
- Stericup E
- Filter Membrane Types
- Express PES,Durapore PVDF
- Filter Sizes
- 0.22 µm,0.45 µm
- Volume Capacity
- Up to 2L,Up to 10L,Up to 20L
- Filter Device Types
- Stericup Quick Release,Stericup E,Sterivex
- Bottle Compatibility
- 20 to 67 mm diameter bottles
- Membrane Options
- Polyethersulfone (PES),Polyvinylidene fluoride (PVDF)