Automatic vial capping system

Ensure precise capping and sealing for sterile vial production with a compact, high-speed solution that integrates seamlessly into aseptic lines, enhancing efficiency and maintaining product integrity.

Caps, Stoppers, and Seals Vials Efficiently

The AS-2 HYGEIA from Siempharma is an automatic capping and sealing solution tailored for high-precision packaging of pharmaceuticals, nutraceuticals, and cosmetics. This compact monobloc machine excels in stoppering and alu-sealing vials, accommodating volumes up to 500ml while adhering to aseptic conditions. The AS-2 supports full or partial rubber stoppering, complemented by flawless alu-sealing for both traditional and flip-off caps. Configured with an intermittent motion system, it capably manages high-speed operations and integrates seamlessly with your existing production line via included infeed and outfeed conveyor systems. The unit is CFR21 part 11 / EU ANNEX 11 compliant, and manufactured to meet GMP standards, ensuring regulatory adherence across industries. Its modular construction, featuring a robust AISI 304 stainless steel frame and FDA-approved contact parts, ensures easy cleaning and maintenance. With an intuitive touch screen HMI interface, operators can quickly learn and configure the machine, optimizing performance and efficiency. Designed with Industry 4.0 compatibility, the AS-2 HYGEIA can be installed under various environmental control systems, including LAF, open RABS, and closed RABS, to suit your operational needs.

Benefits

  • Ensures product integrity and compliance with aseptic capping and sealing.
  • Increases operational efficiency through high-speed intermittent motion.
  • Simplifies training and operation with an intuitive touch screen interface.
  • Facilitates quick changeovers and reduced downtime with easy-size parts and maintenance.
  • Enhances production flexibility with compatibility across various environmental systems.

General


Applications
Nutraceuticals,Cosmetics,Pharmaceuticals
End products
Serum and lotion vials,Liquid foundation vials,Lyophilized vials,Vitamin supplements in vials,Herbal extract vials,Sterile injectable vials
Steps before
Cleaning,Sterilization,Vial Preparation
Steps after
Inspection,Leak Testing,Labeling,Packaging
Input ingredients
empty vials,rubber stoppers,alu-caps
Output ingredients
closed vials,capped vials,vials with rubber stoppers,vials with alu-seals
Market info

Technical Specifications


Automation
Automatic intermittent motion
Capacity
Small to large volume vials (up to 500ml)
Changeover time
Easy change size parts
Cleaning method
Easy cleaning and maintenance operations
User interface
Touch Screen HMI
Compliance
CFR21 part 11 / EU ANNEX 11 ready
Compliance
INDUSTRY 4.0 standard
Construction material
AISI 304 stainless steel
Vial compatibility
Vials without rubber stopper or alu-cap
Stopper type
Full or partial rubber stoppering
Sealing type
Alu-sealing with traditional or flip-off all-caps

Operating Characteristics


Automation level
Automatic intermittent motion
Batch vs. continuous operation
Batch
CIP/SIP
Easy cleaning
Cleaning method
Manual
Changeover time
Easy change size parts
Energy efficiency
INDUSTRY 4.0 standard compliant

Physical Characteristics


Compact footprint
Ultra-compact layout
Construction Material
AISI 304 stainless steel
Modular System
Intermittent motion monobloc
Safety Features
Tempered glass doors with safety interlock switches
Contact Material
FDA or other approved materials
Customization Options
Possibility to install under LAF,open RABS,closed RABS or Isolator
Control Interface
Touch Screen HMI

Custom Options


Control panel type
User-friendly and intuitive Touch Screen HMI
Integration possibilities
Possibility to install the machine under LAF,open RABS,closed RABS or Isolator
Compliance,Certifications
CFR21 part 11 / EU ANNEX 11 ready
Compliance,Certifications
Machine compliant with the INDUSTRY 4.0 standard
Compliance,Certifications
Manufactured according to CE rules
Material option
All parts in contact with the product are in FDA or other approved materials