Vial capping for small volume parenteral

Ensure precise sealing and contamination-free environments for small volume parenterals with this cutting-edge vial capping technology, designed to enhance the efficiency and reliability of your aseptic filling line.

Caps and Seals Vials Aseptically

The CAPSY-LC from Marchesini Group is a high-performance rotary vial capping machine tailored for the pharmaceutical and biotech industries. Specializing in aseptic sealing of Small Volume Parenterals (SVPs), it employs a balcony-style vial transport system ensuring air flow laminarity crucial for sterility. The machine offers robust applications in filling, capping, and sealing of products like insulin and vaccine vials. With an output of up to 24,000 pieces per hour, the CAPSY-LC integrates seamlessly into automated lines with features like brushless motor-controlled vial spinning, automatic capping pressure, and stopper position controls. Its compact design includes an integrated alu-cap pre-feeder, while its wash-in-place technology accelerates cleaning cycles. Compliant with GMP standards, it supports integration under oRABS, cRABS, and Isolators, making it ideal for maintaining operational environment integrity. The use of no-particle alu-sealing technology assures contamination-free operations, all backed by Marchesini’s engineering support for customized solutions.

Benefits

  • Enhances sterility with controlled air flow laminarity and no-particle sealing technology.
  • Maximizes production efficiency with throughput up to 24,000 vials per hour.
  • Minimizes contamination risks through easy integration under sterile barrier systems.
  • Reduces cleaning time with efficient wash-in-place technology.
  • Ensures operational precision with automatic capping pressure and stopper controls.

General


Applications
Vaccines,Aseptic products,Biopharmaceuticals,Small volume parenterals,Pharmaceuticals
End products
Glucagon vials,Adrenaline ampoules,Insulin vials,Antibiotic vials,Blood coagulant vials,Flu vaccines,Heparin injection vials,Monoclonal antibodies,Cancer treatment vials,Ophthalmic solutions
Steps before
Washing,Sterilizing,Ampoules Filling and Sealing
Steps after
Inspection,Packaging,Labelling
Input ingredients
Small Volume Parenteral (SVP),vials,alu-caps,stoppers
Output ingredients
capped vials,alu-sealed vials
Market info
Marchesini is renowned for manufacturing high-quality packaging machinery for the pharmaceutical and cosmetics industries, offering innovative, customized solutions with advanced automation and technology.

Technical Specifications


Output (Pieces/h)
up to 24,000
Vial Capacity
2R / 500 ml
Automation
Automatic capping pressure control
Stopper Presence Control
Automatic
Alu-cap Presence Control
Automatic
Vial Rejection
Automatic rejection of faulty vials
Cleanability
Quick wash-in-place or traditional cleaning
Decontamination Cycle
Quicker by VHP
Vial Transport
Balcony Style for laminarity
Integration
Easy under oRABS,cRABS,Isolator
Alu-cap Sorting System
Totally integrated on board

Operating Characteristics


Working mechanism
Rotary capping
Integrated steps
Vial transport,capping,and inspection
CIP/SIP
Wash-in-place available
Automation level
Automatic with brush-less motors
Batch vs. continuous operation
Inline continuous
Cleaning method
Wash-in-place or traditional cleaning
Changeover time
Quick changeover
Automation level
Automatic capping pressure control

Material Compatibility


Biological compatibility
Suitable for aseptic processing
Cleanability
Quick and efficient wash-in-place
Corrosive resistance (e.g. acids)
High resistance to chemical agents
Density/particle size
0

Product type Characteristics


Container type
Vials

Physical Characteristics


Machine footprint
Compact
Control panel type
Touchscreen
Vertical Wall Mounting
Yes
Balcony Style vial transport
Yes
Discharge method
Automatic rejection of faulty vials
Integration type
oRABS,cRABS,and Isolator

Custom Options


Integration possibilities
oRABS,cRABS,Isolator
Compact footprint
Alu-cap pre-feeder and sorting system integrated on board
Vertical Wall Mounting
Mechanical parts assembled on backside
Balcony Style vial transport
Ensures laminar airflow