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dlf-pcr

DLF-PCR

The essential objectives of containment are personnel protection and preventing the release of toxic or infectious material into the environment. Containment is also used to prevent a product or sample from contamination by the external environment. In the chemical and pharmaceutical industries, containment solutions are used to protect the personnel from airborne particles of hazardous substances, as powders or liquids are handled or transferred during processing.

Containment

A biosafety cabinet is an enclosed, ventilated workspace for safely working with materials potentially contaminated with pathogens in the laboratory. A laminar flow bench is an enclosed space designed to prevent contamination of sensitive samples; it draws in air through a HEPA filter and directs it smoothly towards the user to protect the sample from contamination. The choice of a suitable biosafety cabinet or bench depends on the type of sample and the defined biosafety level ranging from 1 (unlikely to cause disease) to 4 (causes very serious human or animal disease).

Batch

HEPA filtered vertical laminar airflow (down flow) creates an ISO 14644-1 (Class 5) work area and prevents ambient air entering the work area, ensures product protection.


<h2>Create a class 5 work environment for non-hazardous materials</h2>
Telstar vertical clean benches ensure optimum product protection with HEPA filtration. Heavy duty construction and reliability make them convenient in the long term for all sectors of application and environments. Vertical laminar flow cabinets can be made in special sizes and can be customized to suit particular applications.

Special models have been developed to create the optimum work environment for PCR (polymerase chain reactions) and for lab environments. Down flow booth models are available that work fully with recirculated laminar HEPA filtered air (Telstar V-100) or partially recirculated laminar HEPA filtered air (Telstar V30/70).

Vertical laminar flow cabinet

liquid

solid

HEPA filtered horizontal laminar airflow (crossflow) creates an ISO 14644-1 (Class 5) work area and prevents ambient air entering the work area, ensures product protection.


<h2>Particularly well adapted to hospital, control laboratories and life science environments</h2>
Horizontal Laminar Flow benches from Telstar Life-Science have a wide and high working space with a continuously flushed frontward by a particle free HEPA filtered and laminar airflow; which speed prevents contamination from operator and lab environment. The laminarity of the flow prevents cross contamination between the items handled in the working space.

Offering the highest product protection possible in an open system. It makes them particularly suitable for the handling of non-hazardous products, sensible to dust and/or to contamination such as injectable medicines, cell and tissue cultures, food sample preparation for sterility testing as well as micromechanics, optics, electronics.

Horizontal laminar flow benches

HEPA filtered horizontal laminar airflow (cross-flow) creates an optimized free space for manipulation with ISO 14644-1 (Class 5) conditions.


<h2>Compact booth that offers easy access to manipulate non-hazardous products</h2>
Mini-H from Telstar Life-Science are Horizontal laminar flow benches which offer the highest product protection versus dust and contamination in an open cabinet for non-hazardous samples such as cell and tissue cultures, food testing preparation, injectable medicine preparation. It also fits for micromechanics, optics and electronics.

The Compact horizontal laminar flow bench comes with HEPA filtered air; it's particle free and flushes the product preparation space with laminar flow, preventing direct or cross-contamination.

Thanks to its very compact size, Telstar Mini-H permits the installation of a product protection cabinet near the place where the product is utilized.

Compact horizontal laminar flow bench

This handy device offers the most advanced features in product-operator protection and user-friendly ergonomics to allow best working conditions and results.


<h2>Protect to the operator, product/materials and environment under class II conditions</h2>
BioULTRA from Telstar Life-Science is a top range class II cabinet aimed to provide protection to the operator, product/materials and environment. It is certified according to European Standard EN 12469 and also meets NSF 49 (class II type A2 /B3) and BS 5726:2005 main requirements. It is suitable for handling pathogenic agents of levels 1, 2 and 3 in the fields of pharmaceutical, academic research centers, biotechnology, hospital and medical labs, QA control labs.

Motorized sash window with inflatable gasket, filter clogging calculation and a simplified fumigation process minimize maintenance cost and time.

Remote PC Ultra logger control suitable for P3 lab.

Microbiological safety cabinet class II

For the manipulation of hazardous substances utilized during the preparation of cytotoxic medicines as prescribed in several European countries.


<h2>Ideal class II configuration for reinforced biosafety and maintenance cost savings</h2>
The CytoUltra from Telstar Life-Science has 3 filters, which third HEPA filter set below the work bench of CytoUltra traps the contaminants thus preventing them from reaching the plenum, the main HEPA filter and the HEPA exhaust filter, such reinforced safety is required for the handling of highly toxic compounds.

Certified EN 12469 Class II and DIN 12980 for Cytotoxics, CytoUltra offers the most advanced features in product and operator protection and in ergonomics to allow best working conditions.

Third HEPA filter stage easily replaced in the unit basement and filter clogging calculation minimize maintenance cost and time. Remote PC Ultra logger control is suitable for P3 lab.

Biosafety cabinet class II for cytotoxic medicines

Ideal for products which have no biological risk but require high sterile conditions.


<h2>Start working in the lab under high sterile conditions</h2>
Sterilator from Telstar Life-Science is a positive-pressure isolator, which provides laminar airflow in the working chamber, making it ideal for products that require high sterile conditions.

This equipment not only provides a high level of containment against external contamination, but avoids the risk of cross contamination as they provide laminar air flow to the working chamber.

Positive pressure isolator

Specially designed for the handling of microbiological agents, when working with indigenous or exotic pathogenic agents that pose a moderately high risk of serious or potentially lethal disease to the operator when inhaled.


<h2>Offering Class III biological safety to operator, product and environment</h2>
The Biological safety cabinet class III from Telstar Life-Science is a laboratory isolator designed according EN 12469, offering an ergonomically designed totally sealed which keep the user completely separated from the product by a physical barrier when total containment and user protection is required.

Series MSC III is a completely gastight cabinet. The dangerous biological agents enter the work area by a hatch, the operator uses gloves (assembled to the front of the cabinet) to research the biological agents. While working, potential contaminated air is controlled by airflow and negative air pressure.

Biological safety cabinet class III

Used for products biologically hazardous, that also require minimized cross contamination.


<h2>Start working with hazardous substances thanks to this perfectly adapted device</h2>
The Cytolator from Telstar Life-Science is a negative-pressure isolator, which works providing laminar airflow within the working chamber while ensures a minimum of cross contamination. The Cytolator main chamber pressure (vs. ambient) is negative to the room. Both the main chamber and pass-through are always negative to the room, and provide protection to the product, user and environment.

An additional third HEPA H14 prefiltration stage right below the workbench adapts the isolator to the requirements in the manipulation of hazardous substances like the preparation of cytotoxic medicines as prescribed in some countries recommendations.

Negative pressure isolator

Sensitive bioprocess applications requires equipment that will not interfere with the chemical and biological processes being carried out.  At the same time, production bioprocesses, in particular those that involve peristaltic pumping, require robust tubing not prone to wear or mechanical failures.  Traditional transfer tubing for these more rigorous ans sensitive bioprocesses often proves inadequate.


<h2>A robust biocompatible tube designed for longevity in production peristaltic pumping applications</h2>
JM BioConnect is known for certified top of industry quality and customer service including very short lead times.  The company offers tubing solutions specifically designed for use in peristaltic pumps in bioprocess production environments. The tubes are of the PharMed BPT brand and are completely bio-compatible and less permeable to gasses and vapors than traditional silicone tubes.  This makes the PharMed BPT tubes ideal for protecting sensitive biological processes like cell culture, fermentation, separation, synthesis, and purification.  At the same time, they have been formulated for enhanced flex and wear characteristics allowing trouble free used in peristaltic pumping applications.  The combination of these qualities increases the efficiency of the bio-production process by reducing down time from tubing failure without making any sacrifices in bio compatibility.

Biocompatible tubing for peristaltic pumps

Biotech equipment is used for the processing of biological organisms to develop new healthcare-related products. Selecting suitable equipment requires consideration of the process objectives and requirements, the scale of production, and the specific health and safety regulations. Biotech equipment finds applications production of biodegradable plastics, and biofuels as well as in health care.

Bioprocessing

The fermentation process stimulates enzymatic activity in organic substrates to transform their chemical composition. Fermentation is aided by storying the biomaterials in anaerobic environments, allowing the microorganisms to decompose their nutrient structures. The process is integral to some of the most popular products throughout time such as wine, beer, cheese, and kimchi. But besides the food sector, fermentation is also an important stage in the industrial manufacturing of chemicals, pharmaceuticals, and biofuels.

Fermentation

Purification is the removal of contaminating substances and by-products to increase the level of purity of the desired substance. Considerations for choosing a suitable purification system in the industry, include the physical state of the mixture, the desired product, required level of purity, the type of mixture, heat sensitivity of the product, number of purification steps needed, and the production volume. Industrial purification systems are used for the production of pure water in the food pharmaceutical and biotech industries.

Purification

Dry fogging provides safe, effective microbiological cleaning of critical areas in biotech, pharmaceutical and other industries where the highest levels of sterility are required. Let's find out if this compact disinfection system can serve you.


<h2>Thoroughly decontaminate exposed surfaces</h2>
The DosyMist by SolidFog uses H2O2 atomisation under controlled release to provide airborne decontamination and hinder the spread of bacterial growth on surfaces, filters, materials and equipment. A small, easy to manoeuvre unit made of medical grade stainless steel, the DosyMist digitally tracks its operation using Siemens PLC control for consistency of results. Designed to operate effectively on areas from 2 to 100 m³, this system has applications in the agri-food and pharmaceutical industries, health facilities, public and industrial premises and
research laboratories.

Compact H2O2 disinfection system

Cleaning equipment is used to wash or disinfect machinery and the production area. It may also be used to sterilize the product, equipment, tools, or work surfaces and to purify or clean the product by removing impurities. Choosing a suitable cleaning system depends on the type of product or equipment to be cleaned, the sensitivity of the product to heat, pressure, and chemicals, and the level of sterility desired.

Cleaning

Disinfection systems use antimicrobial agents to destroy microorganisms found on equipment, floors, walls, and other surfaces. In industry, disinfection of machinery and the production area is important to prevent product contamination which may lead to spoilage and health hazards for workers and the consumer. The choice of a disinfection system depends on the level of disinfection needed, the disinfecting agent, the size of the area or objects to be treated, and the suitable method of treatment such as sterilization, pasteurization, exposure to ultraviolet light, or chemical fogging.

Disinfection

Sterilization is a key procedure across many manufacturing processes. Sterilization processes and methods are found in food, healthcare, pharma as well as in the medical field. Specialized equipment is used to kill harmful microorganisms from containers before you fill them up with your goods. Most sterilization equipment employs high temperature pressurized steam to completely eliminate bacteria and disinfect surfaces from any spores. Other methods include radiation sterilization or the use of chemicals such as hydrogen peroxide for disinfection.

Sterilizing

Biosafety cabinets

Some of the vaccines in use today were originally developed decades ago. But advances in research and vaccine manufacturing equipment provide immunizations from bacterial and viral diseases to more people every year. The Covid-19 pandemic highlights the urgent need to scale up the production of vaccines and ensure a reproducible manufacturing environment.

Vaccines

Insulin is a hormone that controls blood glucose levels produced by the beta cells in the pancreas. As a medication, insulin was discovered by Frederick Banting and Charles Best in 1921, for which they were awarded a Nobel Prize in 1923. The insulin production process involves manipulating the biological precursor to insulin and cultivating it inside bacteria.

Insulin

The word parenteral comes from Greek and means outside the intestine (para=outside and enteron=intestine). In fact, when it comes to parenterals, we are referring to those dosage forms that are administered directly into the bloodstream using a hypodermic needle, avoiding going through the gastrointestinal tract. Using parenteral filling equipment, parenteral solutions are placed in containers such as vials, syringes, or ampoules.

Parenterals

During crime scene investigations in any movie, you've probably seen forensic scientists collecting evidence and biological samples in small containers. Here, these are the vials, used to store medicines, especially in liquid form, or laboratory samples. Often made of glass or plastic, vials can be labeled as single-dose vials or sterilized and reused more than once. They are also available with various closure systems depending on the material and storage requirements.

Vials

Pharmaceutical cartridges are glass containers of cylindrical shape, suitable for liquid or solid pharmaceutical dosage forms. Generally, these are designed for a specific apparatus such as pre-filled syringes and autoinjectors. Drugs that can be placed in cartridges using a pharmaceutical cartridge filling equipment include insulin, dental anesthesia, and other emergency drugs for allergies.

Pharmaceutical cartridges

API making equipment must observe rigorous quality standards across the entire manufacturing process. The pharmacodynamic properties of active pharmaceutical ingredients make them highly sensitive to their environment, making API production a tightly regulated field.

Active pharmaceutical ingredients (API)

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