Small scale pharmaceutical filler and stoppering system

Optimize your R&D operations with a versatile filling and stoppering machine designed for seamless small-scale liquid, powder, or tablet processing, ensuring precision and consistency across diverse formulations.

Fills, Stopers, and Caps Various Formulations

The Hull LyoStar® BI I/L Filler from SP Industries is designed for small-scale pharmaceutical and biotech operations, offering precise filling, stoppering, and capping for a diverse range of formulations. Engineered to meet cGMP and GAMP5 compliance, this machine operates efficiently, filling up to 3000 vials per hour with either peristaltic or piston pumps. Its servo-driven motion-control system ensures smooth handling and accurate filling, crucial for therapeutic proteins, antibody-drug conjugates, and custom pharmaceutical formulations. Adaptable to different container sizes from 2 mL to 100 mL via a simple star wheel change, it integrates seamlessly with laboratory and pilot-scale operations. The machine also supports integration with open or closed Restricted Access Barrier Systems (RABS) and isolation technology for enhanced product protection. Designed for flexibility, it addresses the specific needs of pharmaceutical manufacturers, R&D labs, and compounding pharmacies, all while allowing for efficient changeovers and recipe storage.

Benefits

  • Enhances operational efficiency by filling up to 3000 vials per hour.
  • Supports diverse production needs with easy changeovers for different container sizes.
  • Ensures product integrity through precise stoppering and capping mechanisms.
  • Seamlessly integrates with advanced containment systems for superior safety.
  • Minimizes setup time with recipe storage for multiple batch configurations.

General


Applications
Compounding pharmaceuticals,Liquid formulations,Pharmaceutical tablets,Adc production,Diagnostics,Therapeutic proteins
End products
Coated tablets,Monoclonal antibodies,Custom pharmaceutical formulations,Antibody-drug conjugates,Diagnostic reagents,Injectable vaccines
Steps before
Purification,Preparation of Vials,Cleanroom Preparation
Steps after
Freeze Drying,Sealing,Crimping,Labeling,Inspection,Packing
Input ingredients
liquid,powder,tablets,2 mL to 100 mL containers,serum stoppers,lyophilization stoppers
Output ingredients
filled vials,stoppered vials,capped vials
Market info

Technical Specifications


Filling Speed
Up to 3000 vials per hour
Container Volume
2 mL to 100 mL
Pump Options
Peristaltic or Piston
Compliance
cGMP and GAMP5

Operating Characteristics


Automation level
PLC / Servo-driven
Batch vs. continuous operation
Batch
Changeover time
Quick and easy
Energy efficiency
Efficient
Cleaning method
Manual

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Product type
Liquid,powder,tablet

Physical Characteristics


Machine footprint
Small
Compact footprint
Small
Container size range
2 mL to 100 mL
Discharge method
Stoppering/Capping