Small scale pharmaceutical filler and stoppering system
Optimize your R&D operations with a versatile filling and stoppering machine designed for seamless small-scale liquid, powder, or tablet processing, ensuring precision and consistency across diverse formulations.

Fills, Stopers, and Caps Various Formulations
The Hull LyoStar® BI I/L Filler from SP Industries is designed for small-scale pharmaceutical and biotech operations, offering precise filling, stoppering, and capping for a diverse range of formulations. Engineered to meet cGMP and GAMP5 compliance, this machine operates efficiently, filling up to 3000 vials per hour with either peristaltic or piston pumps. Its servo-driven motion-control system ensures smooth handling and accurate filling, crucial for therapeutic proteins, antibody-drug conjugates, and custom pharmaceutical formulations. Adaptable to different container sizes from 2 mL to 100 mL via a simple star wheel change, it integrates seamlessly with laboratory and pilot-scale operations. The machine also supports integration with open or closed Restricted Access Barrier Systems (RABS) and isolation technology for enhanced product protection. Designed for flexibility, it addresses the specific needs of pharmaceutical manufacturers, R&D labs, and compounding pharmacies, all while allowing for efficient changeovers and recipe storage.
Benefits
- Enhances operational efficiency by filling up to 3000 vials per hour.
- Supports diverse production needs with easy changeovers for different container sizes.
- Ensures product integrity through precise stoppering and capping mechanisms.
- Seamlessly integrates with advanced containment systems for superior safety.
- Minimizes setup time with recipe storage for multiple batch configurations.
- Applications
- Compounding pharmaceuticals,Liquid formulations,Pharmaceutical tablets,Adc production,Diagnostics,Therapeutic proteins
- End products
- Coated tablets,Monoclonal antibodies,Custom pharmaceutical formulations,Antibody-drug conjugates,Diagnostic reagents,Injectable vaccines
- Steps before
- Purification,Preparation of Vials,Cleanroom Preparation
- Steps after
- Freeze Drying,Sealing,Crimping,Labeling,Inspection,Packing
- Input ingredients
- liquid,powder,tablets,2 mL to 100 mL containers,serum stoppers,lyophilization stoppers
- Output ingredients
- filled vials,stoppered vials,capped vials
- Market info
- Filling Speed
- Up to 3000 vials per hour
- Container Volume
- 2 mL to 100 mL
- Pump Options
- Peristaltic or Piston
- Compliance
- cGMP and GAMP5
- Automation level
- PLC / Servo-driven
- Batch vs. continuous operation
- Batch
- Changeover time
- Quick and easy
- Energy efficiency
- Efficient
- Cleaning method
- Manual
- Density/particle size
- 0.5–2.5 g/cm³ / 50–1000 µm
- Product type
- Liquid,powder,tablet
- Machine footprint
- Small
- Compact footprint
- Small
- Container size range
- 2 mL to 100 mL
- Discharge method
- Stoppering/Capping