Nested syringe filling and stoppering system
Optimize your syringe production with precise filling and stoppering, ensuring consistent dosage and quality in every batch, ideal for high-demand pharmaceutical formulations.

Fills and Stopper Nested Syringes
The FS-50 CHIRON from Siempharma is designed to transform your syringe filling and stoppering operations with precision and efficiency. Its compact, automatic system smoothly integrates into pharmaceutical, nutraceutical, and cosmetic production lines, with a focus on handling both glass and plastic syringes, cartridges, and nested vials. The machine employs volumetric or peristaltic pumps for accurate liquid dosage and features an intermittent motion capping group for immediate stoppering. The FS-50 CHIRON supports various end-products, from injectable nutrient supplements to pre-filled cosmetic syringes, and can process up to high-speed throughput. Engineered for easy maintenance, it features AISI 304 stainless steel construction, intuitive touch screen controls, and compliance with GMPs, CFR 21 Part 11, and EU ANNEX 11. Integration options like LAF, RABS, or Isolator setup ensure both flexibility and safety, making it a reliable choice for high-quality production demands.
Benefits
- Enhances production efficiency by automating syringe handling seamlessly.
- Minimizes contamination risks with compact, closed-system design.
- Reduces operational costs through low-maintenance requirements and user-friendly controls.
- Ensures regulatory compliance and product safety with GMP and FDA-approved materials.
- Adapts to various production needs with customizable integration options.
- Applications
- Nutraceuticals,Cosmetics,Pharmaceuticals
- End products
- Pre-filled cosmetic injectables,Plastic syringes with hormone treatments,Injectable vitamin serums,Single-use glass syringes containing antibiotics,Injectable nutrient supplements,Nested vials for oncology medications,Pre-filled syringes with hyaluronic acid for skincare,Pre-filled syringes for vaccines
- Steps before
- Sterilization,Material Preparation,Nest Loading,In-Line Loading
- Steps after
- Stoppering,Capping,Nest Re-insertion,In-Line Unload,Final Packaging
- Input ingredients
- nested single-use syringes,glass syringes,plastic syringes,cartridges,vials,tubs
- Output ingredients
- filled syringes,stoppered syringes,filled cartridges,stoppered cartridges,filled vials,stoppered vials
- Market info
- Automation
- Automatic intermittent motion
- Filling method
- Volumetric / peristaltic pumps
- Stoppering Method
- Intermittent motion capping group
- Material
- AISI 304 stainless steel
- Compatibility with Syringe Material
- Glass / Plastic
- Design Compliance
- GMP standards
- Machine Standards
- INDUSTRY 4.0
- Operation Method
- Touch Screen HMI
- Nest Loading
- Automatic in-line
- Nest Positioning
- Automatic centring on table
- Stoppering Timing
- Immediate after filling
- Nest Unload
- Automatic in-line
- Size Changeover
- Easy change size parts
- Cleanability
- Easy cleaning and maintenance
- Panel Material
- Tempered glass doors
- Safety Feature
- Safety interlock switches
- System Installation
- Under LAF / open RABS / closed RABS / Isolator
- CFR/EU Compliance
- CFR21 part 11 / EU ANNEX 11
- Working mechanism
- Automatic monobloc
- Integrated steps
- Filling and stoppering
- Automation level
- Automatic
- Batch vs. continuous operation
- Intermittent motion
- Changeover time
- Easy change size parts
- Cleaning method
- Easy cleaning operations
- Biological compatibility
- FDA approved materials
- Cleanability
- Easy cleaning and maintenance
- Corrosive resistance (e.g. acids)
- AISI 304 stainless steel
- Container type
- Glass / Plastic Syringes
- Filling purpose
- Syringe filling and stoppering
- Compact footprint
- Yes
- Control panel type
- Touch Screen HMI
- Material
- AISI 304 stainless steel
- Safety interlock switches
- Tempered glass doors
- Control panel type
- Touch Screen HMI
- Integration possibilities
- LAF / open RABS / closed RABS / Isolator
- Pump type
- Volumetric / peristaltic
- Material of construction
- AISI 304 stainless steel
- User interface
- User-friendly and intuitive
- Compliance compatibility
- CFR21 part 11 / EU ANNEX 11
- Safety features
- Safety guards with interlock switches
- Layout
- Ultra-compact
- Maintenance
- Easy cleaning and maintenance
- Size changeover
- Easy change size parts