Nested syringe filling and stoppering system

Optimize your syringe production with precise filling and stoppering, ensuring consistent dosage and quality in every batch, ideal for high-demand pharmaceutical formulations.

Fills and Stopper Nested Syringes

The FS-50 CHIRON from Siempharma is designed to transform your syringe filling and stoppering operations with precision and efficiency. Its compact, automatic system smoothly integrates into pharmaceutical, nutraceutical, and cosmetic production lines, with a focus on handling both glass and plastic syringes, cartridges, and nested vials. The machine employs volumetric or peristaltic pumps for accurate liquid dosage and features an intermittent motion capping group for immediate stoppering. The FS-50 CHIRON supports various end-products, from injectable nutrient supplements to pre-filled cosmetic syringes, and can process up to high-speed throughput. Engineered for easy maintenance, it features AISI 304 stainless steel construction, intuitive touch screen controls, and compliance with GMPs, CFR 21 Part 11, and EU ANNEX 11. Integration options like LAF, RABS, or Isolator setup ensure both flexibility and safety, making it a reliable choice for high-quality production demands.

Benefits

  • Enhances production efficiency by automating syringe handling seamlessly.
  • Minimizes contamination risks with compact, closed-system design.
  • Reduces operational costs through low-maintenance requirements and user-friendly controls.
  • Ensures regulatory compliance and product safety with GMP and FDA-approved materials.
  • Adapts to various production needs with customizable integration options.

General


Applications
Nutraceuticals,Cosmetics,Pharmaceuticals
End products
Pre-filled cosmetic injectables,Plastic syringes with hormone treatments,Injectable vitamin serums,Single-use glass syringes containing antibiotics,Injectable nutrient supplements,Nested vials for oncology medications,Pre-filled syringes with hyaluronic acid for skincare,Pre-filled syringes for vaccines
Steps before
Sterilization,Material Preparation,Nest Loading,In-Line Loading
Steps after
Stoppering,Capping,Nest Re-insertion,In-Line Unload,Final Packaging
Input ingredients
nested single-use syringes,glass syringes,plastic syringes,cartridges,vials,tubs
Output ingredients
filled syringes,stoppered syringes,filled cartridges,stoppered cartridges,filled vials,stoppered vials
Market info

Technical Specifications


Automation
Automatic intermittent motion
Filling method
Volumetric / peristaltic pumps
Stoppering Method
Intermittent motion capping group
Material
AISI 304 stainless steel
Compatibility with Syringe Material
Glass / Plastic
Design Compliance
GMP standards
Machine Standards
INDUSTRY 4.0
Operation Method
Touch Screen HMI
Nest Loading
Automatic in-line
Nest Positioning
Automatic centring on table
Stoppering Timing
Immediate after filling
Nest Unload
Automatic in-line
Size Changeover
Easy change size parts
Cleanability
Easy cleaning and maintenance
Panel Material
Tempered glass doors
Safety Feature
Safety interlock switches
System Installation
Under LAF / open RABS / closed RABS / Isolator
CFR/EU Compliance
CFR21 part 11 / EU ANNEX 11

Operating Characteristics


Working mechanism
Automatic monobloc
Integrated steps
Filling and stoppering
Automation level
Automatic
Batch vs. continuous operation
Intermittent motion
Changeover time
Easy change size parts
Cleaning method
Easy cleaning operations

Material Compatibility


Biological compatibility
FDA approved materials
Cleanability
Easy cleaning and maintenance
Corrosive resistance (e.g. acids)
AISI 304 stainless steel

Product type Characteristics


Container type
Glass / Plastic Syringes
Filling purpose
Syringe filling and stoppering

Physical Characteristics


Compact footprint
Yes
Control panel type
Touch Screen HMI
Material
AISI 304 stainless steel
Safety interlock switches
Tempered glass doors

Custom Options


Control panel type
Touch Screen HMI
Integration possibilities
LAF / open RABS / closed RABS / Isolator
Pump type
Volumetric / peristaltic
Material of construction
AISI 304 stainless steel
User interface
User-friendly and intuitive
Compliance compatibility
CFR21 part 11 / EU ANNEX 11
Safety features
Safety guards with interlock switches
Layout
Ultra-compact
Maintenance
Easy cleaning and maintenance
Size changeover
Easy change size parts