Semiautomatic lu-177 production and dispensing plant

Extracts, Purifies, and Dispenses Lu-177 Radioisotopes

The Lu-177 N.C.A. Semiautomatic Production and Dispensing Plant, offered by Comecer, is a sophisticated system meticulously crafted to meet the demanding needs of radiopharmaceutical manufacturers and nuclear medicine facilities. This system is distinguished by its dual-chamber hot cell configuration—one chamber for extraction and purification, and the other for dispensing and terminal sterilization. It handles the complete workflow from separating Ytterbium-176 from Lutetium-177 to preparing terminally sterilized vials of Lu-177 radioisotope therapy doses.

Equipped with tele-manipulators, robotic dispensers, and semi-automatic dispensing technology, the system ensures precise micro-dose handling while maintaining safety with lead shielding and acid-proof fluoropolymer coatings. Its integration capability with customer-specific modules for automated extraction and purification enhances flexibility. The process automation is complemented by control systems for batch processing and remote handling, all while maintaining rigorous compliance with cGMP standards. Furthermore, the plant features a saturated steam autoclave and supports productivity of 50 vials in 8 hours, optimizing both efficiency and throughput in production. Customization options allow adaptation to specific operational needs, supported by comprehensive engineering support.