Automated visual inspection for small volume parenterals

Ensure the integrity of high-value parenteral drugs by detecting cosmetic and particulate defects with precision, reducing false rejects and improving detection rates in small volume, high mix production environments.

Inspects and Analyzes Vials for Defects

The VISION CAV 600 from WILCO AG is an automated visual inspection platform designed specifically for inspecting vials containing liquid or lyophilized parenteral products. This system utilizes a static optical path to minimize vibrations, ensuring maximum inspection reliability without requiring manual adjustments during format changes. By employing customized inspection algorithms, the VISION CAV 600 achieves exceptional detection rates while reducing false rejects.

Ideal for pharmaceutical and biotech industries, this platform inspects for particles and cosmetic defects in vaccines, monoclonal antibodies, and other critical drug products. It supports scalable processing, making it adaptable to new inspection tasks and formats. The platform’s vial transportation system gently handles containers, mitigating inspection-result-affecting factors like bubbles and vibrations.

Engineered to meet GMP standards, the VISION CAV 600 offers easy cleaning and swift format changeovers, enhancing operational efficiency. With up to 13 inspection stations and high-resolution cameras, it provides comprehensive analysis, including cosmetic inspection, particle characterization, and color and turbidity measurement. The system’s servo-driven spinning stations and vacuum gripper systems enable precise and smooth handling, catering to high-speed inline operations. Suitable for diverse production environments, the platform integrates seamlessly into existing lines while ensuring consistent, high-quality outputs.

Benefits

  • Enhances product quality with reliable defect detection and reduced false rejects.
  • Streamlines production with fast format changeovers, minimizing downtime.
  • Ensures operator independence, enhancing flexibility for clinical and small-scale production.
  • Meets stringent regulatory standards with GMP-compliant design.
  • Maintains high product integrity through gentle and controlled vial handling.

General


Applications
Parenteral drug products,Liquid formulations,Lyophilized products,Vials,High mix - low volume parenterals,Biopharmaceuticals,Small volume parenterals,Pharmaceuticals
End products
Insulin vials,Gene therapy products,Vaccines,Lyophilized vaccines,Monoclonal antibodies,Chemotherapy drugs,Customized parenteral solutions,Liquid injectable drugs,Reconstitutable lyophilized drugs,Clinical trial drugs
Steps before
Filling,Lyophilization,Formulation
Steps after
Packing,Labeling,Sterilization
Input ingredients
vials,liquid pharmaceuticals,lyophilized products,small volume parenterals,high mix - low volume parenterals
Output ingredients
inspected vials,detected cosmetic defects,inspected particles,quality assured pharmaceuticals
Market info

Technical Specifications


Automation
Fully-automated
Machine design
GMP compliant
Inspection speed
Up to 20 vials per minute
Inspection type
Vision-based
Container type
Vials
Container size
2R - 30R
Particle inspection method
Image subtraction with optical path OptiX
Spinning stations
Servo-driven spinning stations
Camera resolution
High-resolution
Sorting module
Configurable with up to 8 outlets
Platform scalability
Scalable processing units
Inspection stations
Up to 13 stations
Compact footprint
Designed for minimal space usage

Operating Characteristics


Automation level
Fully Automated
Batch vs. continuous operation
Batch
Changeover time
Fast effectuation
CIP/SIP
Manual / Simple Cleaning
Cleaning method
CIP / Manual
Container transportation system
Gentle vial handling
Integrated inspection steps
Cosmetic and Particle Inspection
Scalability
Scalable processing units

Material Compatibility


Density/particle size
0.5–2.5 g/cm³ / 50–1000 µm

Product type Characteristics


Parenteral Product Type
Small volume parenterals,High mix - low volume parenterals

Physical Characteristics


Machine footprint
Compact design
Control panel type
Operator-centered handling
Discharge method
Gentle vial transportation
Container transportation system
Vacuum gripper system
Compact footprint
Smallest possible
Protection from environment
Cameras protected from dust

Custom Options


Control panel type
OptiX vision system
Scalability
Supports scalable processing units
Inspection algorithm selection
Project specific customization
Sorting module
Configurable with up to 8 outlets
Spinning profiles
Adjustable for particle characteristics
Product configuration
AI-supported baselines
Format change flexibility
Quick adjustment without downtime
Camera station configuration
Customizable for high-resolution imaging