Sterile robotic filling for ready-to-use vials and syringes
In pharmaceutical and biotech manufacturing, ensuring sterility during the filling process of ready-to-use vials and syringes is critical. Challenges include minimizing contamination risk, achieving high filling accuracy, and adhering to cGMP (Current Good Manufacturing Practice) standards.
Automate precise and sterile filling operations
The Flex-Line™ by Comecer is a comprehensive solution that integrates a robotic filling system and an aseptic isolator. This system is specifically designed to handle and fill ready-to-use vials and prefilled syringes with high precision. The isolator ensures that the entire process occurs in a sterile environment, compliant with ISO5 / Grade A air quality standards, thanks to its laminar flow throughout the area. The filling system uses either peristaltic or volumetric piston pumps based on customer needs, ensuring high accuracy and minimal contamination risk. With integrated in-process control by load cells for statistical check weighing, the Flex-Line™ guarantees consistent and precise filling. Additionally, the system’s design makes it versatile, allowing quick changeovers to accommodate different container types with minimal downtime. Suitable for R&D operations and pilot-scale sterile production, it features automatic or semi-automatic No-Touch-Transfer procedures to minimize human intervention.
Benefits
- High filling accuracy due to advanced pump systems
- Maintains sterile conditions with cGMP-compliant isolator
- Versatile design for quick changeovers
- Integrated in-process control for consistent quality
- Reduces contamination risk with minimal human intervention